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1. Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand…

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki PAN

Call: OPUS 4, Panel: ST4

2. Characterization of protein-protein interaction network of the Escherichia coli replication complex comonents under diff…

Principal investigator: dr Monika Katarzyna Glinkowska

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 7, Panel: NZ2

3. Integrative methods for modeling protein-protein complexes and multimolecular assemblies

Principal investigator: prof. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: SHENG 2, Panel: NZ2

4. Design of RNA–protein interactions and complexes

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 29, Panel: NZ1

5. Doubly knotted proteins - frontiers of topological complexity of proteins

Principal investigator: dr hab. Joanna Ida Sułkowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 16, Panel: NZ1

6. An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-…

Principal investigator: prof. Józef Adam Liwo

Uniwersytet Gdański, Wydział Chemii

Call: HARMONIA 5, Panel: ST4

7. Development of a new scoring function for models of protein-small molecule complexes and its use for studying the mechan…

Principal investigator: dr Irina Tuszyńska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: PRELUDIUM 2, Panel: NZ2

8. Methods for the similarity analysis of low complexity regions in proteins

Principal investigator: dr Patryk Paweł Jarnot

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Call: PRELUDIUM 20, Panel: ST6

9. LCRPlatform: new algorithms and methods for the comprehensive identification, categorization, and annotation of protein …

Principal investigator: dr hab. Marcin Maciej Grynberg

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST6

10. Mechanostability of proteins and their complexes

Principal investigator: Mateusz Kazimierz Sikora

Instytut Fizyki PAN

Call: PRELUDIUM 1, Panel: ST3

11. Combining Rosetta method with deeply coarse grained SURPASS model into a novel multiscale algorithm for modeling protein…

Principal investigator: dr hab. Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 15, Panel: ST6

12. Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc …

Principal investigator: prof. Maciej Leszek Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Call: OPUS 8, Panel: ST4

13. The complex nature of multidomain proteins: the unmasked activity of human Dicer ribonuclease – expect the unexpected

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28, Panel: NZ2

14. Investigating the potential of protein-pectin complexes to improve the functional properties of 3D printing inks

Principal investigator: Magdalena Urszula Trusińska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Call: PRELUDIUM 23, Panel: NZ9

15. Fundaments of nanosilver toxicity - mechanism of nanoparticle dissolution, complexes with glutathione and interference w…

Principal investigator: prof. Wojciech Bal

Instytut Biochemii i Biofizyki PAN

Call: PRELUDIUM BIS 3, Panel: ST4

16. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

Principal investigator: dr Monika Anna Hałat

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

Call: SONATINA 5, Panel: ST4

17. Structural-functional analysis of nucleoprotein complexes of plasmid Rep proteins and ssDNA DUE origin region.

Principal investigator: dr Katarzyna Ewa Węgrzyn

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: SONATA 13, Panel: NZ1

18. Multiple functions of RFC protein complex in the architecture and dynamics of replication factories in cell nuclei

Principal investigator: Maciej Włodzimierz Krupa

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 11, Panel: NZ3

19. Self-aggregation of protein complexes: virus capsids and amyloids

Principal investigator: dr Panagiotis Theodorakis

Instytut Fizyki PAN

Call: POLONEZ 1, Panel: ST3

20. Molecular characterization of Chd64 and FKBP39 proteins, key components of multiprotein complex mediating juvenile hormo…

Principal investigator: prof. Andrzej Janusz Ożyhar

Politechnika Wrocławska, Wydział Chemiczny

Call: OPUS 3, Panel: NZ1

21. Targeting nucleic acid-protein complexes with small molecules using a deep-learning framework

Principal investigator: dr Ryhor Nikalayeu

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATINA 7, Panel: NZ1

22. Investigation of senescence-associated alterations in the nuclear protein complex (NPC) composition and nuclear transpor…

Principal investigator: dr hab. Anna Bielak-Żmijewska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 23, Panel: NZ5

23. The Elongator protein complex integrates regulation of transcription and translation during photomorphogenesis in Arabid…

Principal investigator: dr hab. Magdalena Paula Wołoszyńska

Uniwersytet Przyrodniczy we Wrocławiu

Call: OPUS 22, Panel: NZ1

24. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST4

25. Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell …

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: SONATA 15, Panel: ST4

26. Identification and functional characterization of proteins interacting with cohesin complex in yeast Saccharomyces cerev…

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 16, Panel: NZ2

27. Role of the exocyst complex in transport of cytoplasmic proteins to the primary cilium

Principal investigator: Sylwia Maria Niedziółka

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 15, Panel: NZ3

28. Novel functions of alpha-dystrobrevin-1 and dystroglycan protein complex in regulation of neuromuscular junctions

Principal investigator: dr hab. Tomasz Jacek Prószyński

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 15, Panel: NZ3

29. Synthesis of complex silver and zinc compounds based on caseins and whey' proteins and silver and zinc oxide nanoparticl…

Principal investigator: dr Paweł Piotr Pomastowski

Uniwersytet Mikołaja Kopernika, Interdyscyplinarne Centrum Nowoczesnych Technologii

Call: OPUS 14, Panel: ST4

30. Regulation of photomorphogenesis in Arabidopsis thaliana via Elongator - the protein complex epigenetically regulating g…

Principal investigator: dr hab. Magdalena Wołoszyńska

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

Call: OPUS 14, Panel: NZ1

31. Integrative modeling and structure determination of macromolecular complexes comprising RNA and proteins

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: MAESTRO 9, Panel: NZ1

32. Lsr2 protein as a global chromosomal organizer and transcription factor in Mycobacterium - an interplay of Lsr2 with SMC…

Principal investigator: prof. Jolanta Zofia Zakrzewska-Czerwińska

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 13, Panel: NZ1

33. The role of the ESCRT-0 protein complex in viral RNA-dependent activation of TLR3 signaling in murine astrocytes

Principal investigator: Matylda Barbara Mielcarska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

Call: PRELUDIUM 12, Panel: NZ6

34. The role of E3 ligase complexes in integration of protein homeostasis and aging.

Principal investigator: dr Wojciech Mieczysław Pokrzywa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 12, Panel: NZ3

35. Significance of the hDpy30/srGAP2 protein complex for adhesion/migration of mammalian cells

Principal investigator: dr Martyna Węglewska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 11, Panel: NZ3

36. Interdomain allosteric communication in Rad50 protein and its role in genome maintence by Mre11 complex

Principal investigator: prof. Artur Krężel

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 11, Panel: NZ1

37. Role of SWI/SNF remodeling complexes, CTCF1 protein , long non-coding RNA transcribed from BRCA1/NBR2 bidirectional prom…

Principal investigator: prof. Janusz Aleksander Siedlecki

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: OPUS 6, Panel: NZ2

38. The role of the light-dependent chlorophyll biosynthesis in the regulation of the biosynthesis and assembly of pigment-p…

Principal investigator: dr hab. Beata Joanna Myśliwa-Kurdziel

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA BIS 3, Panel: NZ3

39. Genes encoding for iodothyronine deiodinase, mRNA and protein levels in the complex mechanisms of the risk of recurrent …

Principal investigator: dr Elżbieta Gałecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Call: OPUS 4, Panel: NZ7

40. Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

Principal investigator: dr Agnieszka Ludwików

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 3, Panel: NZ3

41. Disrupting the Toxic NMDAR/TRPM4 Protein Dialogue as a Novel Neuroprotective Strategy: Development of Small-Molecule Inh…

Principal investigator: Katarzyna Aleksandra Szafrańska

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7

42. Determination of the dynamics of changes in protein networks interacting with selected isoforms of the protein phosphata…

Principal investigator: dr hab. Danuta Anna Babula-Skowrońska

Instytut Genetyki Roślin PAN

Call: OPUS 26, Panel: NZ9

43. Molecular basis of carnitine transporters OCTN2 and ATB(0,+) trafficking to plasma membrane of astrocytes: The role of p…

Principal investigator: prof. Katarzyna Anna Nałęcz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 4, Panel: NZ3

44. Structure prediction of proteins and large protein assemblies guided by low-resolution or/and sparse experimental data.

Principal investigator: dr Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 1, Panel: NZ2

45. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

Principal investigator: dr Natalia Anna Skrzypczak

Fundacja Uniwersytetu im. Adama Mickiewicza

Call: SONATINA 9, Panel: ST5

46. Structure-based dynamical models of large and complex biomolecular systems

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Call: OPUS 8, Panel: ST3

47. Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

Principal investigator: dr hab. Jarosław Błaszczyk

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 3, Panel: ST4

48. Characterization of regulatory mechanisms of exocyst complex in plant cells

Principal investigator: Michał Jan Michalak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 2, Panel: NZ3

49. Multidomain and multimeric proteins: structural and mechanical insights

Principal investigator: dr Bartosz Jan Różycki

Instytut Fizyki PAN

Call: OPUS 3, Panel: NZ1

50. Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex…

Principal investigator: Michał Taube

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Call: PRELUDIUM 3, Panel: ST3

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