Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Novel functions of alpha-dystrobrevin-1 and dystroglycan protein complex in regulation of neuromuscular junctions

2018/29/B/NZ3/02675

Keywords:

neuromuscular junction muscle dystrobrevin dystroglycan

Descriptors:

  • NZ3_6: Cell neurobiology
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Tomasz Prószyński 

Number of co-investigators in the project: 4

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 714 000 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2022-04-23

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer z oprogramowaniem (2 szt.) (6 880 PLN)
  2. Monitor.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. A Role for Caveolin-3 in the Pathogenesis of Muscular Dystrophies
    Authors:
    Bhola Shankar Pradhan, Tomasz J. Prószyński
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 45313), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21228736 - link to the publication
  2. An improved method for culturing myotubes on laminins for the robust clustering of postsynaptic machinery
    Authors:
    Marcin Pęziński, Patrycja Daszczuk, Bhola Shankar Pradhan, Hanns Lochmüller, Tomasz J. Prószyński
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 45304), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-61347-x - link to the publication
  3. Cortactin interacts with αDystrobrevin-1 and regulates neuromuscular junction morphology
    Authors:
    Teresa De Cicco, Marcin Pęziński, Olga Wójcicka, Klemens Rottner, and Tomasz J. Prószyński
    Academic press:
    Cellular & Molecular Biology Letters , Wydawca: Springer
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. Perisynaptic schwann cells - The multitasking cells at the developing neuromuscular junctions
    Authors:
    Paloma Alvarez-Suareza, Marta Gawora, Tomasz J. Prószyński
    Academic press:
    Seminars in Cell & Developmental Biology (rok: 2020, tom: 104, strony: 31-38), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.semcdb.2020.02.011 - link to the publication
  5. Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice
    Authors:
    SV Doss, S Barbat-Artigas, M Lopes, BS Pradhan, TJ Prószyński, R Robitaille, G Valdez
    Academic press:
    Front Cell Dev Biol (rok: 2022, tom: 10, strony: 45307), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2022.838612 - link to the publication
  1. A novel function of SH3BP2 in the organization of postsynaptic acetylcholine receptors
    Authors:
    B.S. Pradhan, K. Bernadzki, Y. Bandaruk, J. Krzemień, and T.J. Prószyński
    Conference:
    NMJ RESEARCH CONFERENCE (rok: 2021, ), Wydawca: The University of Edinburgh
    Data:
    konferencja 5-7th October 2021
    Status:
    Published
  2. Amotl1: a novel synaptic protein important for mice social behavior and the brain organization
    Authors:
    Joanna Krzemień, Katarzyna Rojek, Maciej Winiarski, Paweł Boguszewski, Ewelina Knapska, Tomasz J.Prószyński
    Conference:
    FENS 2019 (rok: 2019, ), Wydawca: Serbian Neuroscience Society, Belgrade
    Data:
    konferencja 43656
    Status:
    Published
  3. Drebrin as a cytoskeletal regulator at the neuromuscular junction
    Authors:
    Paloma Alvarez-Suarez, Marta Gawor, and Tomasz J. Prószynski
    Conference:
    4th PhD Student Conference of the Nencki Institute (rok: 2019, ), Wydawca: Nencki Institute
    Data:
    konferencja 43740
    Status:
    Published
  4. The function of SH3BP2 in the organization of the NMJ
    Authors:
    B.S. Pradhan, K. Bernadzki, Y. Bandaruk, A. Siudzińska, J. Krzemień, A. Bachmatiuk, G. Chodaczek, and T.J. Prószyński
    Conference:
    Molecular and Cell Biology of the Neuromuscular System (rok: 2022, ), Wydawca: University of Basel
    Data:
    konferencja September 18-23, 2022
    Status:
    Published

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