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1. New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an…

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 1, Panel: ST5

2. Synthesis and evaluation of a novel toolkit for biology and biotechnology based on adenine nucleotides analogs

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Call: SONATA BIS 5, Panel: ST5

3. Functional glycol nucleic acid (fun-GNA) nucleosides, nucleotides and oligos: synthesis and properties

Principal investigator: prof. Konrad Maciej Kowalski

Uniwersytet Łódzki, Wydział Chemii

Call: OPUS 15, Panel: ST5

4. Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

Principal investigator: dr Karolina Ewa Piecyk

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 11, Panel: ST5

5. New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro…

Principal investigator: Sylwia Ciechanowicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 9, Panel: ST5

6. Adenosine 5'-phosphoramidate as a novel signaling molecule; Study of enzymatic synthesis of this nucleotide and analysis…

Principal investigator: prof. Andrzej Bolesław Guranowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

Call: OPUS 3, Panel: NZ1

7. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping …

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 16, Panel: ST5

8. Modified (oligo)nucleotides for photo-controlled manipulation of mRNA

Principal investigator: dr Marcin Warmiński

Uniwersytet Warszawski, Wydział Fizyki

Call: SONATA 18, Panel: ST4

9. Synthesis of trimethyl cap analogs modified with molecular rotors and their application in nuclear transport studies

Principal investigator: dr Błażej Wojtczak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA 13, Panel: ST5

10. Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t…

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 6, Panel: ST5

11. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

Principal investigator: dr hab. Marcin Krzysztof Chmielewski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 4, Panel: ST5

12. Chemically modified mRNA for studies on cellular processes and therapeutic applications

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 11, Panel: ST5

13. mRNA 5' end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 17, Panel: ST4

14. N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules …

Principal investigator: Magdalena Materna

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 12, Panel: ST5

15. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in…

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 5, Panel: ST5

16. Aryl nucleoside phosphoroamidates - a new generation of anti-HIV pronucleotides.

Principal investigator: prof. Jacek Antoni Stawiński

Instytut Chemii Bioorganicznej PAN

Call: OPUS 1, Panel: ST5

17. Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of…

Principal investigator: Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 1, Panel: NZ1

18. Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Call: SONATA 1, Panel: ST5

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