Projects funded by the NCN


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153 projects found matching your search criteria :

  1. The role of free fatty acid receptors in pathophysiology of the functional gastrointestinal tract disorders: new therapi...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Maciej Stanisław Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  2. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  3. Do metal nanoparticles affect the biosynthesis of bioactive plant metabolites? - studies on an in vitro culture model of...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Szopa

    Uniwersytet Jagielloński, Collegium Medicum

  4. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Patryk Pyka

    Uniwersytet Jagielloński, Collegium Medicum

  5. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny

  6. Step beyond classical lipophilicity - modeling of phospholipids affinity using immobilized artificial membranes chromato...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr hab. Krzesimir - Ciura

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  7. Exploring the unknown drug-like chemical space: new classes of sulfoximine derivatives and their biological activities.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Maciej Filip Dawidowski

    Warszawski Uniwersytet Medyczny

  8. Identification of new biofilm-associated genes of Campylobacter jejuni.

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: dr hab. Ewa Wałecka-Zacharska

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

  9. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Partial agonists of alpha-2 adrenoceptors as new perspective of the effective and safe in reducting body weight and obes...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Magdalena Bogumiła Dudek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  12. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Krzysztof Tomasz Kamiński

    Uniwersytet Jagielloński, Collegium Medicum

  13. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. New Frontiers of EU Mobility and Health Protection in the Covid-19 Era: Safeguarding Shield or Paradigm(s) Shift?

    Call: OPUS 23 , Panel: HS5

    Principal investigator: dr Patrycja Karolina Dąbrowska-Kłosińska

    Akademia Leona Koźmińskiego

  15. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Maciej Spiegel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

  16. Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Maciej Antoni Wnuk

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  17. Biomedical and chemometric assessment of the new analytical platform in the study of endogenous substances as potential ...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Lucyna Konieczna

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  18. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Katarzyna Florczak-Substyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  19. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  20. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Anna Wardowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  21. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. The role of intestinal CYP2E1 in pathophysiology of the gastrointestinal tract disorders: new therapies for leaky gut sy...

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Maciej Stawnisław Sałaga

    Uniwersytet Medyczny w Łodzi

  24. New synthetic resveratrol derivatives with potential anti-ageing and anti-cancer properties

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: dr Justyna Mikuła-Pietrasik

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

  25. New graphene-based approach targeting the prion-like propagation of α-synuclein in Parkinson's disease.

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kujawska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  26. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  27. New 3-methoxypropanamide derivatives in search of effective substances for the treatment of neurological diseases - epil...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marcin Konrad Jakubiec

    Uniwersytet Jagielloński, Collegium Medicum

  28. Development of new implantable drug forms, biodegradable nanofibers containing selected betulin derivatives in order to ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Janusz Edward Kasperczyk

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

  29. The development of the new safe and controlled anticoagulant therapy with the use of cationically-modified polymers in t...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Andrzej Mogielnicki

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  30. New antimycotic polycations - synthesis, chemical characterization, toxicity and antifungal spectrum

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Kamil Krzysztof Kamiński

    Uniwersytet Jagielloński, Wydział Chemii

  31. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Dawid Marcin Panek

    Uniwersytet Jagielloński, Collegium Medicum

  32. A new class of antimicrobial compounds. Design, synthesis and study of the mechanism of action.

    Call: PRELUDIUM BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  33. New generation teranostatic nanocarriers for detection, diagnosis andneuroprotective treatment of ischemic stroke brain ...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Piotr Warszyński

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

  34. Influence of the route of administration of new psychoactive substances on their metabolic profile

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Magdalena Anna Popławska

    Narodowy Instytut Leków

  35. A new approach to imaging and rapid microbiome identification in evaluation radiotherapy effects

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Dorota Katarzyna Gabryś

    Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy, Oddział w Gliwicach

  36. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Anna Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  37. New therapies of opioid use disorder

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Wojciech Barnaba Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

  38. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  39. Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Janusz Marcin Dąbrowski

    Uniwersytet Jagielloński, Wydział Chemii

  40. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Marek Andrzej Jamrozik

    Uniwersytet Jagielloński, Collegium Medicum

  41. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Marta Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  42. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Andrzej Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  43. Processing fluid: A new laboratory tool for diagnostic and basic investigation

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Hanna Marta Turlewicz-Podbielska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  44. New iron chelators from thiosemicarbazone group in photodynamic therapy

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Robert Bogumił Gawecki

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  45. Fluorine substitution – a new algorithm for increasing biological activity

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Wojciech Pietruś

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Marek Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  48. Assessment of the hepatoprotective effect of AP39, a new H2S donor, in a model of autoimmune hepatitis in mice.

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: dr Katarzyna Paulina Przejczowska-Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  49. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. DEVELOPMENT AND VALIDATION OF NEW LC-MS/MS METHOD FOR DETERMINATION OF UNBOUND TACROLIMUS IN PLASMA IN CYP 3A5 EXPRESSOR...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Karola Warzyszyńska

    Warszawski Uniwersytet Medyczny