Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Biomedical and chemometric assessment of the new analytical platform in the study of endogenous substances as potential cancer biomarkers

2011/03/B/NZ7/02333

Keywords:

biomedical analysis chemometric analysis endogenous substances cancer

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Lucyna Konieczna 

Number of co-investigators in the project: 3

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 223 600 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-12-21

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. koncentrator próżniowy (65 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Analytical approach to determining human biogenic amines and their metabolites using eVol microextraction in packed syringe coupled to liquid chromatography mass spectrometry method with hydrophilic interaction chromatography column
    Authors:
    L. Konieczna, A. Roszkowska, A. Synakiewicz, T. Stachowicz-Stencel, E. Adamkiewicz-Drożyńska, T. Bączek
    Academic press:
    Talanta (rok: 2016, tom: 150, strony: 331-339), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2015.12.056 - link to the publication
  2. Classification of LC column based on the QSRR method and selectivity toward moclobemide and its metabolites
    Authors:
    A. Plenis, I. Olędzka, T. Bączek
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2013, tom: 78-79, strony: 161-169), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2013.02.020 - link to the publication
  3. Cyclodextrin-modified MEKC method for quantification of selected acidic metabolites of catecholamines in the presence of various biogenic amines. Application to diagnosis of neuroblastoma
    Authors:
    N. Miękus, P. Kowalski, I. Olędzka, A. Plenis, E. Bień, A. Miękus, M. Krawczyk, E. Adamkiewicz-Drożyńska, T. Bączek
    Academic press:
    Journal of Chromatography B (rok: 2015, tom: 1003, strony: 27-34), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2015.09.003 - link to the publication
  4. The LC–MS method for the simultaneous analysis of selected fat-soluble vitamins and their metabolites in serum samples obtained from pediatric patients with cystic fibrosis.
    Authors:
    L. Konieczna, A. Roszkowska, A. Szlagatys-Sidorkiewicz, T. Bączek
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2016, tom: 124, strony: 374-381), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2016.03.021 - link to the publication
  5. Advanced assessment of the endogenous hormone level as a potential biomarker of the urogenital tract cancer
    Authors:
    L. Konieczna, M. Belka, T. Bączek, M. Ruszkowski, W. Struck, M. Markuszewski, R. Kaliszan, M. Markuszewski
    Academic press:
    Combinatorial Chemistry & High Throughput Screening (rok: 2013, tom: vol. 16; No. 6, strony: 463-472), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    ISSN: - link to the publication
  6. Optimization of a pre-MEKC separation SPE procedure for steroid molecules in human urine samples
    Authors:
    I. Olędzka, P. Kowalski, Sz. Dziomba, P. Szmudanowski, T. Bączek
    Academic press:
    Molecules (rok: 2013, tom: 18, strony: 14013-14032), Wydawca: Open Access ISSN 1420-3049
    Status:
    Published
    DOI:
    10.3390/molecules181114013 - link to the publication
  7. Comparison of core-shell and totally porous ultra high performance liquid chromatographic stationary phases based on their selectivity towards alfuzosin compounds
    Authors:
    J. SzulferA. Plenis, T. Bączek
    Academic press:
    Journal of Chromatography A (rok: 2014, tom: 1346, strony: 69-77), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2014.04.046 - link to the publication
  8. Hydrophilic interaction chromatography combined with dispersive liquid-liquid microextraction as a preconcentration tool for the simultaneous determination of the panel of underivartized neurotransmitters in human urine samples
    Authors:
    L. Konieczna, A. Roszkowska, M. Niedźwiecki, T. Bączek
    Academic press:
    Journal of Chromatography A (rok: 2016, tom: 1431, strony: 111-121), Wydawca: Elsevier
    Status:
    Published
    DOI:
    org/1016/j.chroma.2015.12.062 - link to the publication

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