Search results

1. Hyphenated separation techniques in the study of the molecular mechanisms of metabolic biotransformation of drugs for ta…

Principal investigator: dr Małgorzata Szultka-Młyńska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: SONATA 12, Panel: ST4

2. Drug metabolizing enzymes (DMEs) in liver pathology, proteomic characteristics, transcriptional and epigenetic regulatio…

Principal investigator: prof. Marek Droździk

Pomorski Uniwersytet Medyczny w Szczecinie

Call: OPUS 19, Panel: NZ7

3. Influence of immobilization on metabolic activity and sensitivity on non-steroidal anti-inflammatory drugs of selected b…

Principal investigator: dr hab. Urszula Irena Guzik

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: OPUS 15, Panel: NZ9

4. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact…

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Call: OPUS 13, Panel: NZ7

5. Novel, chemometrically assisted, metabolic based research strategy in anticancer drug development on the example of benz…

Principal investigator: Mariusz Marcin Belka

Gdański Uniwersytet Medyczny, Wydział Faramcautyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 1, Panel: NZ1

6. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co…

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 26, Panel: NZ7

7. Synthesis and application of new mixed-mode materials to study the metabolism of drugs used in Poland for the treatment …

Principal investigator: dr hab. Sylwia Studzińska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: OPUS 26, Panel: NZ7

8. Biodegradation of selected nootropic drugs and evaluation of their metabolic pathways in context of sewage epidemiology

Principal investigator: Marta Helena Woźniak-Karczewska

Politechnika Poznańska, Wydział Technologii Chemicznej

Call: PRELUDIUM 13, Panel: NZ9

9. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti…

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

10. Electrochemical analysis of drugs of abuse and psychostimulants metabolism with mass spectrometry detection - a step tow…

Principal investigator: Przemysław Jakub Mielczarek

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Call: PRELUDIUM 4, Panel: ST4

11. Transformation of 5'-O-monothiophosphate nucleoside to 5'-O-monophosphate in the cell - possible metabolism of phosphoro…

Principal investigator: dr Agnieszka Krakowiak

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 5, Panel: ST5

12. Comparative mRNA expression, protein abundance and regulatory mechanisms of drug metabolising eznymes and transporters i…

Principal investigator: prof. Marek Droździk

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Call: OPUS 9, Panel: NZ7

13. Parallel microevolution of metabolic plasticity and chemoresistance of cancer cells: a key to understanding cancer relap…

Principal investigator: prof. Jarosław Piotr Czyż

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ3

14. Exploiting the weakness of lymphoma: spectroscopic identification of biomarkers for lymphoma metabolism and inducing its…

Principal investigator: Patrycja Dawiec

Uniwersytet Jagielloński

Call: PRELUDIUM 23, Panel: ST4

15. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of…

Principal investigator: dr hab. Carlo Vascotto

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: OPUS 22, Panel: NZ5

16. CBR1-dependent metabolism and ABCB1-dependent effux of doxorubicin - search for a novel mechanism of reversing resistanc…

Principal investigator: Kamil Tomasz Piska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

17. Tryptophan Metabolites and their Metal Complexes as new drugs for Colorectal Cancer Treatment and Human Gut Microbiota R…

Principal investigator: prof. Beata Izabella Godlewska-Żyłkiewicz

Uniwersytet w Białymstoku, Wydział Chemii

Call: OPUS 20, Panel: ST4

18. Structural insights into the involvement of the RNA degradosome in trans-translation in the light of the antimicrobial a…

Principal investigator: dr Przemysław Adam Płociński

Uniwersytet Łódzki

Call: SONATA BIS 9, Panel: NZ1

19. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective …

Principal investigator: dr Katarzyna Zofia Kuter

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ7

20. Study on metabolism of microorganisms treated with metal nanoparticles, antibiotics, metal ions and their combinations u…

Principal investigator: Agnieszka Maria Rogowska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: PRELUDIUM 13, Panel: ST4

21. Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to…

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska

Call: OPUS 17, Panel: NZ7

22. Genetic background of aminoglycoside-induced hearing loss - mitochondrial and nuclear genes involvement

Principal investigator: dr Małgorzata Aleksandra Rydzanicz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA 5, Panel: NZ5

23. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 13, Panel: NZ7

24. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res…

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 25, Panel: NZ5

25. Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor…

Principal investigator: dr Konrad Mateusz Pakuła

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ1

26. Porphyrazine based catalyst support for biomimetic studies on selected active pharmaceutical ingredients

Principal investigator: Tomasz Władysław Koczorowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM 9, Panel: NZ7

27. The impact of P450 and UGT isoenzyme overexpression on cellular response induced by antitumor acridinone derivatives. Th…

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 5, Panel: NZ3

28. Evaluation of influence of genetic factors associated with transport and metabolizm of immunosuppressive agents on blood…

Principal investigator: prof. Leszek Pączek

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: OPUS 5, Panel: NZ2

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