Electrochemical analysis of drugs of abuse and psychostimulants metabolism with mass spectrometry detection - a step towards predictive toxicology

2012/07/N/ST4/01837

Keywords

Descriptors

  • ST4_9: Elektrochemia, elektrodializa, chemia w mikrostrumieniach
  • NZ4_11: Metabolizm
  • ST4_6: Chemia analityczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Przemysław Jakub Mielczarek

Number of co-investigators in the project: 2

Call

PRELUDIUM 4 – announced on 2012-09-15

Amount awarded
61 350 PLN
Project start date
2013-08-08
Project end date
2014-11-07
Project duration
15 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Blok grzejny z funkcją mieszania (Thermomixer). Cost: 8 157 PLN
  2. Wytrząsarka (Vortex). Cost: 1 440 PLN

Information in the final report

Publication in academic press/journals (5)

  1. Determination of psychostimulants and their metabolites by electrochemistry linked on-line to flowing atmospheric pressure afterglow mass spectrometry

    Authors:
    M. Smoluch, P. Mielczarek, E. Reszke, G. M. Hieftje, J. Silberring
    Academic press:
    Analyst (year: 2014, volume: 139, pages: 4350-4355), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c3an02067c – link to the publication
  2. Electrochemical simulation of cocaine metabolism—a step toward predictive toxicology for drugs of abuse

    Authors:
    P. Mielczarek, H. Raoof, J. H. Kotlinska, P. Stefanowicz, Z. Szewczuk, P. Suder, J. Silberring
    Academic press:
    European Journal of Mass Spectrometry (year: 2014, volume: 20, pages: 279-285), Publisher: IM Publications
    Status:
    Published
    DOI:
    10.1255/ejms.1284 – link to the publication
  3. Plasma-based Ambient Ionization Mass Spectrometry in Bioanalytical Sciences

    Authors:
    M. Smoluch, P. Mielczarek, J. Silberring
    Academic press:
    Mass Spectrometry Reviews (year: 2016, volume: 35, pages: 22-34), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/mas.21460 – link to the publication
  4. Electrochemical generation of selegiline metabolites coupled to mass spectrometry

    Authors:
    P. Mielczarek, M. Smoluch, J. H. Kotlinska, K. Labuz, T. Gotszalk, M. Babij, P. Suder, J. Silberring
    Academic press:
    Journal of Chromatography A (year: 2015, volume: 1389, pages: 96-103), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2015.02.049 – link to the publication
  5. Molecular Scavengers as Carriers of Analytes for Mass Spectrometry Identification

    Authors:
    M. Smoluch, M. Ceglowski, J. Kurczewska, M. Babij, T. Gotszalk, J. Silberring, G. Schroeder
    Academic press:
    Analytical Chemistry (year: 2014, volume: 86, pages: 11226-11229), Publisher: ACS Publications
    Status:
    Published
    DOI:
    10.1021/ac502776z – link to the publication

Book publications / chapters in book publications (1)

  1. Symulacja metabolizmu narkotyków z zastosowaniem elektrochemicznego utleniania

    Authors:
    P. Mielczarek, S. Sobczyk, J. Kotlińska, P. Suder, J. Silberring
    Book:
    Problemy współczesnej elektrochemii (year: 2014, volume: 1, pages: 127-135), Publisher: Wydawnictwo Naukowe AKAPIT
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski