Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Electrochemical analysis of drugs of abuse and psychostimulants metabolism with mass spectrometry detection - a step towards predictive toxicology

2012/07/N/ST4/01837

Keywords:

narcotics psychoactive substances metabolism electrochemistry mass spectrometry

Descriptors:

  • ST4_9: Biological chemistry
  • NZ4_11: Metabolism
  • ST4_6: Instrumental methods in chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Przemysław Mielczarek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 61 350 PLN

Project start date (Y-m-d): 2013-08-08

Project end date (Y-m-d): 2014-11-07

Project duration:: 15 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wytrząsarka (Vortex) (1 440 PLN)
  2. Blok grzejny z funkcją mieszania (Thermomixer) (8 157 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Determination of psychostimulants and their metabolites by electrochemistry linked on-line to flowing atmospheric pressure afterglow mass spectrometry
    Authors:
    M. Smoluch, P. Mielczarek, E. Reszke, G. M. Hieftje, J. Silberring
    Academic press:
    Analyst (rok: 2014, tom: 139, strony: 4350-4355), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c3an02067c - link to the publication
  2. Plasma-based Ambient Ionization Mass Spectrometry in Bioanalytical Sciences
    Authors:
    M. Smoluch, P. Mielczarek, J. Silberring
    Academic press:
    Mass Spectrometry Reviews (rok: 2016, tom: 35, strony: 22-34), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/mas.21460 - link to the publication
  3. Molecular Scavengers as Carriers of Analytes for Mass Spectrometry Identification
    Authors:
    M. Smoluch, M. Ceglowski, J. Kurczewska, M. Babij, T. Gotszalk, J. Silberring, G. Schroeder
    Academic press:
    Analytical Chemistry (rok: 2014, tom: 86, strony: 11226-11229), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/ac502776z - link to the publication
  4. Electrochemical simulation of cocaine metabolism—a step toward predictive toxicology for drugs of abuse
    Authors:
    P. Mielczarek, H. Raoof, J. H. Kotlinska, P. Stefanowicz, Z. Szewczuk, P. Suder, J. Silberring
    Academic press:
    European Journal of Mass Spectrometry (rok: 2014, tom: 20, strony: 279-285), Wydawca: IM Publications
    Status:
    Published
    DOI:
    10.1255/ejms.1284 - link to the publication
  5. Electrochemical generation of selegiline metabolites coupled to mass spectrometry
    Authors:
    P. Mielczarek, M. Smoluch, J. H. Kotlinska, K. Labuz, T. Gotszalk, M. Babij, P. Suder, J. Silberring
    Academic press:
    Journal of Chromatography A (rok: 2015, tom: 1389, strony: 96-103), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2015.02.049 - link to the publication
  1. Symulacja metabolizmu narkotyków z zastosowaniem elektrochemicznego utleniania
    Authors:
    P. Mielczarek, S. Sobczyk, J. Kotlińska, P. Suder, J. Silberring
    Book:
    Problemy współczesnej elektrochemii (rok: 2014, tom: 1, strony: 127-135), Wydawca: Wydawnictwo Naukowe AKAPIT
    Status:
    Published

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