Tryptophan Metabolites and their Metal Complexes as new drugs for Colorectal Cancer Treatment and Human Gut Microbiota Regulation
2020/39/B/ST4/03060
Keywords
Descriptors
- ST4_011: Chemia koordynacyjna, supramolekularna
- ST4_009: Chemia biologiczna
- ST4_017: Reakcje chemiczne: mechanizmy, termodynamika, kinetyka
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Uniwersytet w Białymstoku, Wydział Chemii
Voivodeship: podlaskie
Principal investigator (from the host institution)
prof. Beata Izabella Godlewska-Żyłkiewicz
Number of co-investigators in the project: 6
Call
OPUS 20 – announced on 2020-09-15
- Amount awarded
- 1 838 780 PLN
- Project start date
- 2021-10-01
- Project end date
- 2027-09-30
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Ga complexes of 8-hydroxyquinoline-2-carboxylic acid: Chemical speciation and biological activity
- Authors:
- Izabela Ryza, Claudia Granata, Nadia Ribeiro, Edyta Nalewajko-Sieliwoniuk, Andreas Kießling, Marta Hryniewicka, Winfried Plass, Beata Godlewska-Żyłkiewicz, Sandra Cabo Verde, Demetrio Milea, Sofia Gama
- Academic press:
- Journal of Inorganic Biochemistry (year: 2024, volume: 260, pages: 112670), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jinorgbio.2024.112670 – link to the publication
-
Acid-base properties of hydroxyquinolines in aqueous solution: effect of hydroxyl group position on thermodynamic protonation parameters
- Authors:
- Anna Baryłka, Giuseppina D.G. Santonoceta, Giuseppe Gattuso, Beata Godlewska-Żyłkiewicz, Carmelo Sgarlata, Demetrio Milea, Sofia Gama
- Academic press:
- Journal of Molecular Liquids (year: 2025, volume: 417, pages: 126671), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.molliq.2024.126671 – link to the publication
-
The accurate assessment of the chemical speciation of complex systems through multi-technique approaches
- Authors:
- Anna Baryłka, Beata Godlewska-Żyłkiewicz, Demetrio Milea, Sofia Gama
- Academic press:
- Pure and Applied Chemistry (year: 2024, volume: 96, pages: 597-623), Publisher: De Gruyter
- Status:
- Published
- DOI:
- 10.1515/pac-2024-0206 – link to the publication
-
Protonation equilibria of the tryptophan metabolite 8-hydroxyquinoline- 2-carboxylic acid (8-HQA) and its precursors: A potentiometric and calorimetric comparative study
- Authors:
- Anna Baryłka, Aneta Bagińska-Krakówka, Lidia Zuccarello, Francesca Mancuso, Giuseppe Gattuso, Gabriele Lando, Carmelo Sgarlata, Concetta De Stefano, Beata Godlewska-Żyłkiewicz, Demetrio Milea, Sofia Gama
- Academic press:
- Thermochimica Acta (year: 2023, volume: 730, pages: 179615), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.sab.2020.105922 – link to the publication