Projects funded by the NCN

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Targeting senescent brain cells to improve cognitive function in animal models of ageing and depression

Call: OPUS 18 , Panel: NZ4

Principal investigator: prof. Ewa Zofia Sikora

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Model for antimicrobial peptide-dependent evolution of plastids

Call: PRELUDIUM 18 , Panel: NZ8

Principal investigator: Filip Pietluch

Uniwersytet Wrocławski, Wydział Biotechnologii

Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

Call: PRELUDIUM BIS 1 , Panel: NZ7

Principal investigator: dr hab. Elżbieta - Jankowska

Uniwersytet Gdański, Wydział Chemii

Spatial network model of sequence and structure diversity of Human genome at a population scale

Call: PRELUDIUM BIS 1 , Panel: ST6

Principal investigator: prof. Dariusz Michał Plewczyński

Politechnika Warszawska, Wydział Matematyki i Nauk Informacyjnych

Protaminization of somatic cells nuclei as a model for nuclear reprogramming in somatic cell nuclear transfer.

Call: OPUS 18 , Panel: NZ3

Principal investigator: dr hab. Marta Czernik

Instytut Genetyki i Hodowli Zwierząt PAN

Augmentation of nanoparticle uptake by accounting for tissue mechanics to enhance the effect of brain tumor treatment

Call: UWERTURA 4 , Panel: ST5

Principal investigator: dr Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Nasal administration of probiotics - development of an allergic rhinitis in vitro model and the assessment of probiotic ...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Marcelina Joanna Pyclik

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Cytogenomic analysis of key aspects of nuclear genome organisation in the polyploid model grass Brachypodium hybridum an...

Call: OPUS 16 , Panel: NZ3

Principal investigator: prof. Robert Hasterok

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

In vitro studies of polysaccharide interaction to revise existing models of plant cell wall structure

Call: OPUS 15 , Panel: NZ9

Principal investigator: dr hab. Monika Szymańska-Chargot

Instytut Agrofizyki im. Bohdana Dobrzańskiego PAN

Cell suspension culture of selected Viola L. species to study zinc and lead accumulation and cell tolerance to heavy met...

Call: PRELUDIUM 14 , Panel: NZ8

Principal investigator: dr Klaudia Małgorzata Sychta

Uniwersytet Jagielloński, Wydział Biologii

The role of intercellular communication in somatic embryogenesis induction and somatic embryo formation based on a model...

Call: PRELUDIUM 14 , Panel: NZ3

Principal investigator: Małgorzata Matylda Grzyb

Polska Akademia Nauk

Under the pressure of immunosupression. Mechanisms of loss and regeneration of rare T-cell subpopulations in a model of ...

Call: OPUS 14 , Panel: NZ6

Principal investigator: dr Magdalena Głowala-Kosińska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamila Szostak-Paluch

Politechnika Wrocławska

Mechanisms of cardiovascular complications in rheumatoid arthritis patients: induced pluripotent stem cell-derived cardi...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Monika Biniecka

Kardio-Med Silesia Sp. z o.o.

Evaluation of nervous system cells homeostasis in the experimental in vitro model of cobalamin deficiency as an approach...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Zuzanna Gertruda Rzepka

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

Call: OPUS 12 , Panel: ST4

Principal investigator: dr Piotr Rafał Pięta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Factors influencing effective transport of anticancer drugs through cell membranes studied on the example of the interac...

Call: SONATA 12 , Panel: ST4

Principal investigator: dr Dorota Matyszewska

Uniwersytet Warszawski, Wydział Chemii

Mitofusin 2 role in cell death and cell survival in brain ischemia-reperfusion model

Call: SONATA 12 , Panel: NZ3

Principal investigator: dr Maria Małgorzata Kawalec

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Mesenchymal stem cells as potential immunosuppression in skeletal muscle cell therapy - studies in a mouse model

Call: PRELUDIUM 12 , Panel: NZ6

Principal investigator: dr Barbara Anna Świerczek

Uniwersytet Warszawski, Wydział Biologii

Investigation and implementation of a dynamic model of 1 kW stack of a molten carbonate fuel cell

Call: PRELUDIUM 12 , Panel: ST8

Principal investigator: Arkadiusz Szczęśniak

Politechnika Warszawska, Wydział Mechaniczny Energetyki i Lotnictwa

Effectiveness of anticancer activity of DMU-214 (3'-hydroxy-3,4,5,4'-tetrametoxystilbene) in personalized treatment for ...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Hanna Helena Piotrowska-Kempisty

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

The new model of proton conducting solid oxide fuel cell based on Reduced Order approach

Call: OPUS 12 , Panel: ST8

Principal investigator: dr hab. Jarosław Milewski

Politechnika Warszawska, Wydział Mechaniczny Energetyki i Lotnictwa

Characteriscics of phospholipids oxidation products and determination of toxicity and ability of oxidized phospholipids ...

Call: PRELUDIUM 12 , Panel: NZ9

Principal investigator: Karol Rafał Parchem

Politechnika Gdańska, Wydział Chemiczny

Decoding genetic presisposition to rare neurodevelopmental diseases: Integration of genome, transcriptome and methylome ...

Call: HARMONIA 8 , Panel: NZ2

Principal investigator: dr hab. Paweł Lisowski

Instytut Genetyki i Hodowli Zwierząt PAN

Analysis of the effectiveness of anticancer activity of tyrosine kinase inhibitors combined with nanoparticles in in vit...

Call: SONATA 11 , Panel: ST4

Principal investigator: dr Natalia Piergies

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Label-free vibrational spectroscopy studies and imaging of phase separation in biological membranes and model systems

Call: POLONEZ 2 , Panel: ST4

Principal investigator: dr Luca Quaroni

Uniwersytet Jagielloński, Wydział Chemii

Multi-domain proteins with disordered linkers in cellulose decomposition and cell adhesion

Call: OPUS 11 , Panel: NZ1

Principal investigator: dr Bartosz Jan Różycki

Instytut Fizyki PAN

Effect of dendritic cells co-transduced with lentiviral IL-12 and IL-18 gene carriers for activation of anti-tumor respo...

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Jagoda Izabela Mierzejewska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Protein and gene expression analysis in the course of renal cancer stem-like cells' primary resistance to sorafenib in h...

Call: PRELUDIUM 9 , Panel: NZ5

Principal investigator: Zofia Felicja Bielecka

Wojskowy Instytut Medyczny

Phosphorylation dynamics of STAT1, STAT3 and STAT5 proteins in breast cancer cell lines - systematic experimental and th...

Call: OPUS 9 , Panel: NZ2

Principal investigator: dr Michał Komorowski

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Identification of Regulatory Elements and Transcription Factors Driving Differential Gene Transcription in Neuronal and ...

Call: PRELUDIUM 8 , Panel: NZ2

Principal investigator: Paweł Bednarz

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Structural-funcjonal modifications in natural and model cell membranes of wheat exposed on Fusarium toxin (zearalenone) ...

Call: OPUS 8 , Panel: NZ9

Principal investigator: prof. Maria Anna Filek

Instytut Fizjologii Roślin im. Franciszka Górskiego PAN

Cell cycle regulation of translesion DNA polymerase eta in response to UV radiation, in model cells of Saccharomyces cer...

Call: PRELUDIUM 8 , Panel: NZ1

Principal investigator: Michał Andrzej Płachta

Instytut Biochemii i Biofizyki PAN

Stochastic phenotype switching in growing and dividing bacteria

Call: PRELUDIUM 7 , Panel: NZ2

Principal investigator: dr Joanna Danuta Jaruszewicz-Błońska

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

An examination of the impact of saponins on Langmuir monolayers as model lipid membranes.

Call: PRELUDIUM 7 , Panel: ST4

Principal investigator: Marta Magdalena Orczyk

Politechnika Warszawska, Wydział Chemiczny

Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

Call: PRELUDIUM 7 , Panel: NZ6

Principal investigator: Katarzyna Curzytek

Instytut Farmakologii PAN

Identification of new markers of clear cell carcinoma stem cells - in vivo mouse study employing molecular imaging

Call: OPUS 7 , Panel: NZ1

Principal investigator: prof. Cezary Adam Szczylik

Wojskowy Instytut Medyczny

The role of mTORC1 and mTORC2 complexes in the maintenance of stem-like phenotype of non-small lung adenocarcinoma A549 ...

Call: PRELUDIUM 6 , Panel: NZ3

Principal investigator: Marcin Michał Serocki

Politechnika Gdańska, Wydział Chemiczny

The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r...

Call: OPUS 6 , Panel: NZ4

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Characterizing the functions of plant PCNA1 and PCNA2 proteins using Arabidopsis thaliana as an experimental model

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr Wojciech Kazimierz Strzałka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The key mechanizm for the development of allergy to nickel: A role of the filaggrin fragments, a potential carrier prote...

Call: PRELUDIUM 5 , Panel: NZ6

Principal investigator: Ewa Izabela Podobas

Instytut Biochemii i Biofizyki PAN

Platinum nanoparticles as a self-consumption regulators in the process of cell death with investigation on the glioblast...

Call: PRELUDIUM 5 , Panel: NZ9

Principal investigator: dr Marta Kutwin

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Study of the effect of naphthoflavone structure on aromatase inhibition and cytotoxicity against normal and cancer cell ...

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: Jarosław Tomasz Popłoński

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

Isolation dependent stress and cell malnutrition activation by graphene nanoplatelets as an regulator of autoghagy integ...

Call: PRELUDIUM 5 , Panel: NZ9

Principal investigator: dr Sławomir Jaworski

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Mechanism regulating vitamin D analog cooperation with cytostatics and tyrosine kinase inhibitors in non-small cell lung...

Call: PRELUDIUM 5 , Panel: NZ4

Principal investigator: dr Ewa Agnieszka Maj

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

The effect of probiotic bacteria and Toll-like receptors ligands on growth and differentiation of intestinal epithelial ...

Call: OPUS 5 , Panel: NZ9

Principal investigator: dr hab. Małgorzata Krystyna Pierzchalska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

Study on influence of local anaesthetics on model membranes of nerve cells, mitochondria and erythrocyrtes, with use of ...

Call: PRELUDIUM 5 , Panel: ST5

Principal investigator: Justyna Aleksandra Mildner

Uniwersytet Jagielloński, Wydział Chemii

Analysis of oligodendrocyte differentiation and maturation of St8sia2 knockout mice - a model of polysialylation deficie...

Call: PRELUDIUM 5 , Panel: NZ3

Principal investigator: dr Łukasz Szewczyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego