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Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Interaction of low molecular weight and polymeric cationic compounds with glycosaminoglycans in solution and in selected cell line models

2013/09/D/ST5/03864

Keywords:

glycosaminoglycans polycations polysaccharides cyclodextrins mucopolysaccharidosis

Descriptors:

  • ST5_21:
  • ST5_20:
  • NZ3_2: Cell physiology

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Kamil Kamiński 

Number of co-investigators in the project: 4

Call: SONATA 5 - announced on 2013-03-15

Amount awarded: 423 680 PLN

Project start date (Y-m-d): 2014-02-17

Project end date (Y-m-d): 2017-02-16

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mieszadło magnetyczne z grzaniem (2 szt.) (6 000 PLN)
  2. Spektrometr do pomiarów małych objętości (44 999 PLN)
  3. Wielofunkcyjny czytnik mikropłytek (50 000 PLN)
  4. Zestaw do obrazowania żeli w elektroforezie żelowej (transluminator, kamera CCD, filtry) (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Enhanced delivery of daidzein into fibroblasts and neuronal cells with cationic derivatives of gamma-cyclodextrin for the control of cellular glycosaminoglycans
    Authors:
    Kamil Kamiński, Monika Kujdowicz, Małgorzata Kajta, Maria Nowakowska, Krzysztof Szczubiałka
    Academic press:
    European Journal of Pharmaceutics and Biopharmaceutics (rok: 2015, tom: 91, strony: 111–119), Wydawca: ELSEVIER SCIENCE BV
    Status:
    Published
    DOI:
    10.1016/j.ejpb.2015.02.002 - link to the publication
  2. Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice
    Authors:
    Bartlomiej Kalaska, Kamil Kaminski, Joanna Mikloss, Shin-Ichi Yusa, Emilia Sokolowska, Agnieszka Blazejczyk, Joanna Wietrzyk, Irena Kasacka, Krzysztof Szczubialka, Dariusz Pawlak, Maria Nowakowska, Andrzej Mogielnici
    Academic press:
    Translational Research (rok: 2016, tom: 177, strony: 98–112), Wydawca: ELSEVIER SCIENCE INC
    Status:
    Published
    DOI:
    10.1016/j.trsl.2016.06.009 - link to the publication
  3. Nonclinical Evaluation of Novel Cationically Modified Polysaccharide Antidotes for Unfractionated Heparin
    Authors:
    Bartlomiej Kalaska, Kamil Kaminski, Emilia Sokolowska, Dominik Czaplicki, Monika Kujdowicz, Krystyna Stalinska, Joanna Bereta, Krzysztof Szczubiałka, Dariusz Pawlak, Maria Nowakowska, Andrzej Mogielnicki
    Academic press:
    PLOS ONE (rok: 2015, tom: 10(3), strony: 45312), Wydawca: PUBLIC LIBRARY SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0119486 - link to the publication
  4. The Toxicokinetic Profile of Dex40-GTMAC3 — a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin
    Authors:
    Emilia Sokolowska, BartlomiejKalaska, Kamil Kaminski, Alicja Lewandowska, Agnieszka Blazejczyk, Joanna Wietrzyk, Irena Kasacka, Krzysztof Szczubiałka, Dariusz Pawlak, Maria Nowakowska, Andrzej Mogielnicki
    Academic press:
    Frontiers in Pharmacology (rok: 2016, tom: 7(6), strony: 45305), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fphar.2016.00060 - link to the publication

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