Epigenetic immunomodulation dependent on elements of the microbiome. Model of di

Epigenetic immunomodulation dependent on elements of the microbiome. Model of direct and indirect interactions of Th17 and Treg cells with Staphylococcus aureus in the course of psoriasis.

2020/37/B/NZ5/01029

Keywords

Descriptors

NZ5_001: Etiologia chorób człowieka
NZ5_003: Patogeneza chorób człowieka
NZ5_007: Leczenie chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Instytut Biologii Medycznej PAN

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marcin Marek Ratajewski

Number of co-investigators in the project: 5

Call

OPUS 19 – announced on 2020-03-16

Amount awarded: 1 585 200 PLN
Project start date: 2021-01-26
Project end date: 2026-01-25
Project duration: 60 months (the same as in the proposal)
Project status: Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

α-Hemolysin from Staphylococcus aureus Changes the Epigenetic Landscape of Th17 Cells

Authors:
Pastwińska J, Karwaciak I, Karaś K, Sałkowska A, Chałaśkiewicz K, Strapagiel D, Sobalska-Kwapis M, Dastych J, Ratajewski M.

Academic press:
ImmunoHorizons (year: 2024, volume: 8 (9), pages: 606-621), Publisher: The American Association of Immunologists, Inc.

Status:
Published

DOI:
10.4049/immunohorizons.2400061 – link to the publication
Chlorpromazine, a Clinically Approved Drug, Inhibits SARS-CoV-2 Nucleocapsid-Mediated Induction of IL-6 in Human Monocytes

Authors:
Iwona Karwaciak, Kaja Karaś, Anna Sałkowska, Joanna Pastwińska, Marcin Ratajewski

Academic press:
Molecules (year: 2022, volume: 27, pages: 3651), Publisher: MDPI

Status:
Published

DOI:
10.3390/molecules27123651 – link to the publication

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