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Chemopreventive properties of polysaccharides isolated from edible Basidiomycete mushroom (Boletus edulis). In vitro and molecular studies in colon carcinoma cell culture model

2011/01/M/NZ7/02691

Keywords:

chemoprevention colon cancer Boletus edulis polysaccharides

Descriptors:

  • NZ7_4: Prevention in population health
  • NZ4_11: Metabolism
  • NZ5_9: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wojciech Rzeski 

Number of co-investigators in the project: 6

Call: HARMONIA 1 - announced on 2011-03-15

Amount awarded: 223 600 PLN

Project start date (Y-m-d): 2011-12-20

Project end date (Y-m-d): 2013-12-19

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Boletus edulis biological active biopolymers induce cell cycle arrest in human colon adenocarcinoma cells.
    Authors:
    Lemieszek MK, Cardoso C, Nunes FHFM, Barros AIRNA, Marques G, Pożarowski P, Rzeski W
    Academic press:
    Food and Function (rok: 2013, tom: 4, strony: 575-585), Wydawca: RSCPublishing
    Status:
    Published
    DOI:
    10.1039/c2fo30324h - link to the publication
  2. Boletus edulis ribonucleic acid – a potent apoptosis inducer in human colon adenocarcinoma cells.
    Authors:
    Lemieszek MK, Ribeiro M, Alves HG, Marques G, Nunes FM, Rzeski W
    Academic press:
    Food and Function (rok: 2016, tom: 7, strony: 3163-3175), Wydawca: RSCPublishing
    Status:
    Published
    DOI:
    10.1039/c6fo00132g - link to the publication
  1. Boletus edulis fraction exibitts antiproliferative and proapoptotic properties against colon cancer cell lines LS180 and HT-29.
    Authors:
    Lemieszek MK, Cardoso C, Barros AIRNA, Nunes FHFM, , Marques G, Pożarowski P, Rzeski W
    Conference:
    The 1st Symposium of the Cancer Research Center of Lyon, Lyon, France (rok: 2013, ), Wydawca: CRCL
    Data:
    konferencja 13-15.02.2013
    Status:
    Published
  2. Biopolymers isolated from Boletus edulis as an potent inhibitor of MAPK/ERK pathway in colon cancer cells.
    Authors:
    Lemieszek MK, Nunes FHFM, Rzeski W
    Conference:
    Cancer and Metabolism, Amsterdam, The Netherlands (rok: 2013, ), Wydawca: Abcam plc
    Data:
    konferencja 24-25.06.2013
    Status:
    Published

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