Chemopreventive properties of polysaccharides isolated from edible Basidiomycete mushroom (Boletus edulis). In vitro and molecular studies in colon carcinoma cell culture model
2011/01/M/NZ7/02691
Keywords
Descriptors
- NZ7_4: Prewencja populacyjna
- NZ4_11: Biologia nowotworów
- NZ5_9: Prewencja chorób człowieka
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii
Voivodeship: lubelskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
HARMONIA 1 – announced on 2011-03-15
- Amount awarded
- 223 600 PLN
- Project start date
- 2011-12-20
- Project end date
- 2013-12-19
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (2)
-
Boletus edulis biological active biopolymers induce cell cycle arrest in human colon adenocarcinoma cells.
- Authors:
- Lemieszek MK, Cardoso C, Nunes FHFM, Barros AIRNA, Marques G, Pożarowski P, Rzeski W
- Academic press:
- Food and Function (year: 2013, volume: 4, pages: 575-585), Publisher: RSCPublishing
- Status:
- Published
- DOI:
- 10.1039/c2fo30324h – link to the publication
-
Boletus edulis ribonucleic acid – a potent apoptosis inducer in human colon adenocarcinoma cells.
- Authors:
- Lemieszek MK, Ribeiro M, Alves HG, Marques G, Nunes FM, Rzeski W
- Academic press:
- Food and Function (year: 2016, volume: 7, pages: 3163-3175), Publisher: RSCPublishing
- Status:
- Published
- DOI:
- 10.1039/c6fo00132g – link to the publication
Articles in post-conference publications (2)
-
Biopolymers isolated from Boletus edulis as an potent inhibitor of MAPK/ERK pathway in colon cancer cells.
- Authors:
- Lemieszek MK, Nunes FHFM, Rzeski W
- Conference:
- Cancer and Metabolism, Amsterdam, The Netherlands (year: 2013, pages: 60), Publisher: Abcam plc
- Date:
- conference 24-25.06.2013
- Status:
- Published
-
Boletus edulis fraction exibitts antiproliferative and proapoptotic properties against colon cancer cell lines LS180 and HT-29.
- Authors:
- Lemieszek MK, Cardoso C, Barros AIRNA, Nunes FHFM, , Marques G, Pożarowski P, Rzeski W
- Conference:
- The 1st Symposium of the Cancer Research Center of Lyon, Lyon, France (year: 2013, pages: 101), Publisher: CRCL
- Date:
- conference 13-15.02.2013
- Status:
- Published