Projects funded by the NCN

"Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Impact of pharmacogenetic profiles on depression treatment outcomes

Call: SONATINA 5 , Panel: NZ2

Principal investigator: dr Małgorzata Maria Borczyk

Instytut Farmakologii PAN

The influence of microplastics on the toxicity and fate of selected antidepressants

Call: OPUS 18 , Panel: NZ8

Principal investigator: prof. Grzegorz Leszek Nałęcz-Jawecki

Warszawski Uniwersytet Medyczny

Novel pharmacological strategies for the treatment of depression

Call: OPUS 16 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Anna Maria Rafało-Ulińska

Instytut Farmakologii PAN

Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Zofia Maria Rogóż

Instytut Farmakologii PAN

The importance of interaction between NMDA and AMPA receptors and scaffolding proteins in the excitatory synaptic in the...

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr hab. Magdalena Jolanta Sowa-Kućma

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

The application of a modern chromatographic platform with biodetection: HPLC-DAD/MAO A/ESI-TOF-MS in the antidepressant ...

Call: SONATA 9 , Panel: NZ7

Principal investigator: dr hab. Wirginia Anna Kukuła-Koch

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Selected antidepressants toxicity assessment based on in vitro studies of rat spermatocytes and mouse cell lines.

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Przemysław Paweł Sołek

Uniwersytet Rzeszowski, Wydział Biotechnologii

Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

Call: OPUS 6 , Panel: NZ7

Principal investigator: prof. Franciszek Herold

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

Call: OPUS 5 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

Call: OPUS 5 , Panel: NZ7

Principal investigator: dr hab. Mariusz Papp

Instytut Farmakologii PAN

Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

Call: SONATA 5 , Panel: NZ7

Principal investigator: dr Magdalena Jolanta Sowa-Kućma

Instytut Farmakologii PAN

Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt...

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: Przemysław Paweł Taciak

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

Call: OPUS 4 , Panel: NZ4

Principal investigator: dr Maciej Sławomir Kuśmider

Instytut Farmakologii PAN

Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Maciej Henryk Pawłowski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d...

Call: OPUS 3 , Panel: NZ7

Principal investigator: prof. Małgorzata Maria Filip

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Evaluation of the role of subpopulations of T lymphocytes (Treg: CD4+CD25+, CD4+CD25- i Teff: Th2) in depression using p...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Sylwia Kędracka-Krok

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The role of GPR39 receptor in the mechanism of antidepressant action

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Metabolic stability and inhibition of P450 enzymes in combination with chemometric techniques as a tool for selection of...

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmcautyczny z Oddziałem Medycyny Laboratoryjnej