Projects funded by the NCN

Lactoferrin and versatile polymers as a tool for selective and targeted delivery of anticancer hydrophobic drugs in the ...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Przemysław Gajda-Morszewski

Uniwersytet Jagielloński, Wydział Chemii

Dual-targeted biodegradable polymeric micelles for anticancer drug delivery

Call: SONATA BIS 9 , Panel: NZ7

Principal investigator: dr Katarzyna Jelonek

Centrum Materiałów Polimerowych i Węglowych Polskiej Akademii Nauk

The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

Call: SONATA BIS 9 , Panel: NZ7

Principal investigator: dr hab. Aneta Rogalska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Tomasz Urbaniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

Call: SONATA 14 , Panel: NZ7

Principal investigator: dr hab. Artur Wnorowski

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Application of targeted metabolomic approach in quantitative prospective analysis of nucleosides profiles alterations be...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Małgorzata Artymowicz

Gdański Uniwersytet Medyczny, Wydział Farmacutyczny

Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Barbara Przewłocka

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej Polskiej Akademii Nauk

Peroxiredoxins as potential therapeutic targets in glioblastoma.

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Monika Szeliga

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Gobis

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

The role of MCPIP1 as a potential tumor suppressor during development and treatment of clear cell renal cell carcinoma

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Paulina Marona

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamila Szostak

Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

Molecular background of brain metastases in lung cancer

Call: SONATA 12 , Panel: NZ2

Principal investigator: dr Marcin Nicoś

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

In vitro studies of NaA nanozeolite functionalized with integrins inhibitor- cilengitide and labeled with radium radioiz...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr Sylwia Męczyńska-Wielgosz

Instytut Chemii i Techniki Jądrowej

Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Katarzyna Malarz

Uniwersytet Śląski w Katowicach, Wydział Matematyki, Fizyki i Chemii

Inhibitors of anti-apoptotic proteins from the BCL-2 family as agents enhancing BRAFV600E inhibition in melanoma cells.

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr Mariusz Hartman

Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej

New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Michał Załuski

Uniwersytet Jagielloński, Collegium Medicum, Wydział Farmaceutyczny

Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Bożena Dziadek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Anna Piotrowska-Murzyn

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Anna Więckowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Marek Bajda

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Nanomolecular antioxidants: biological basis of targeted therapy of neurodegenerative diseases.

Call: SONATA BIS 6 , Panel: NZ7

Principal investigator: dr hab. Izabela Sadowska-Bartosz

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Long non-coding RNAs (lncRNA) as treatment efficacy markers in patients with advanced melanoma harboring BRAF mutation.

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr hab. Jacek Mackiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

Nanotheranostics dedicated to targeted anticancer therapies: Novel magnetic hybrid carbon-based materials - synthesis an...

Call: PRELUDIUM 11 , Panel: ST5

Principal investigator: Artur Kasprzak

Politechnika Warszawska, Wydział Chemiczny

New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Krzysztof Walczak

Politechnika Śląska, Wydział Chemiczny

Liposomal theranostic agent for magnetic resonance imaging and photodynamic therapy

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Paulina Skupin-Mrugalska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

Call: SONATA 11 , Panel: NZ5

Principal investigator: dr Bartosz Puła

Instytut Hematologii i Transfuzjologii

Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Barbara Malawska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

INNOvative antiSEPTic agents for a therapy with a broad spectrum of action

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr Sebastian Kraszewski

Politechnika Wrocławska

In vitro and in vivo preclinical studies of NaA nanozeolite functionalized with antibodies anti-PSMA and labeled with ra...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Anna Lankoff

Instytut Chemii i Techniki Jądrowej