Projects funded by the NCN

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85 projects found matching your search criteria :

  1. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  2. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Alicja Gawalska

    Uniwersytet Jagielloński, Collegium Medicum

  3. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Synthetic analogues of opioid growth factor linked to derivatives of glucosamine as a potential compounds for targeted t...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Iwona Inkielewicz-Stępniak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  5. Lactoferrin and versatile polymers as a tool for selective and targeted delivery of anticancer hydrophobic drugs in the ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Przemysław Gajda-Morszewski

    Uniwersytet Jagielloński, Wydział Chemii

  6. Dual-targeted biodegradable polymeric micelles for anticancer drug delivery

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr Katarzyna Jelonek

    Centrum Materiałów Polimerowych i Węglowych Polskiej Akademii Nauk

  7. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Aneta Rogalska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  8. Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Tomasz Urbaniak

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  9. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr hab. Artur Wnorowski

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  10. Application of targeted metabolomic approach in quantitative prospective analysis of nucleosides profiles alterations be...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Małgorzata Artymowicz

    Gdański Uniwersytet Medyczny, Wydział Farmacutyczny

  11. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  13. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  14. Peroxiredoxins as potential therapeutic targets in glioblastoma.

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Monika Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  15. Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Gobis

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  16. The role of MCPIP1 as a potential tumor suppressor during development and treatment of clear cell renal cell carcinoma

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Paulina Marona

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  17. Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: Kamila Szostak-Paluch

    Politechnika Wrocławska

  18. Molecular background of brain metastases in lung cancer

    Call: SONATA 12 , Panel: NZ2

    Principal investigator: dr Marcin Nicoś

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  19. In vitro studies of NaA nanozeolite functionalized with integrins inhibitor- cilengitide and labeled with radium radioiz...

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr Sylwia Męczyńska-Wielgosz

    Instytut Chemii i Techniki Jądrowej

  20. Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Katarzyna Malarz

    Uniwersytet Śląski w Katowicach, Wydział Matematyki, Fizyki i Chemii

  21. Inhibitors of anti-apoptotic proteins from the BCL-2 family as agents enhancing BRAFV600E inhibition in melanoma cells.

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr Mariusz Hartman

    Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej

  22. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Michał Załuski

    Uniwersytet Jagielloński, Collegium Medicum, Wydział Farmaceutyczny

  23. Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Bożena Dziadek

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  24. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  26. Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Marek Bajda

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  27. Nanomolecular antioxidants: biological basis of targeted therapy of neurodegenerative diseases.

    Call: SONATA BIS 6 , Panel: NZ7

    Principal investigator: dr hab. Izabela Sadowska-Bartosz

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  28. Long non-coding RNAs (lncRNA) as treatment efficacy markers in patients with advanced melanoma harboring BRAF mutation.

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Jacek Mackiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

  29. Nanotheranostics dedicated to targeted anticancer therapies: Novel magnetic hybrid carbon-based materials - synthesis an...

    Call: PRELUDIUM 11 , Panel: ST5

    Principal investigator: Artur Kasprzak

    Politechnika Warszawska, Wydział Chemiczny

  30. New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krzysztof Walczak

    Politechnika Śląska, Wydział Chemiczny

  31. Liposomal theranostic agent for magnetic resonance imaging and photodynamic therapy

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Paulina Skupin-Mrugalska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  32. Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Bartosz Puła

    Instytut Hematologii i Transfuzjologii

  33. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Malawska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  34. INNOvative antiSEPTic agents for a therapy with a broad spectrum of action

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr Sebastian Kraszewski

    Politechnika Wrocławska

  35. In vitro and in vivo preclinical studies of NaA nanozeolite functionalized with antibodies anti-PSMA and labeled with ra...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Anna Lankoff

    Instytut Chemii i Techniki Jądrowej

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