Projects funded by the NCN
Mechanisms involved in heme acquisition - potential targets for therapies directed towards reduction of Porphyromonas gingivalis virulence
2021/41/B/NZ6/00702
Keywords:
Porphyromonas gingivalis heme uptake heme metabolism periodontal diseases virulence
Descriptors:
- NZ6_4: Bacteriology
- NZ1_10: Microbiology
- NZ6_8: Other related subjects
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Uniwersytet Wrocławski, Wydział Biotechnologii
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 8
Call: OPUS 21 - announced on 2021-03-15
Amount awarded: 1 789 400 PLN
Project start date (Y-m-d): 2022-01-13
Project end date (Y-m-d): 2026-01-12
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Interplay between Porphyromonas gingivalis hemophore-like protein HmuY and Kgp/RgpA gingipains plays a superior role in heme supplyAuthors:Michał Śmiga, Paulina Ślęzak, Mateusz Wagner, Teresa OlczakAcademic press:Microbiology Spectrum (rok: 2023, tom: 11(2), strony: e0459322), Wydawca: ASM JournalsStatus:PublishedDOI:10.1128/spectrum.04593-22 - link to the publication