Projects funded by the NCN
Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tubercle bacilli interaction with SAA
2016/23/B/NZ7/01204
Keywords:
Mycobacterium tuberculosis human SAA pathogen-host interactions mycobacterial drug targets identification
Descriptors:
- NZ7_12: Prevention of human diseases
- NZ7_16: Other related subjects
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 12 - announced on 2016-09-15
Amount awarded: 1 257 100 PLN
Project start date (Y-m-d): 2017-08-03
Project end date (Y-m-d): 2022-08-02
Project duration:: 60 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- chłodziarko-zamrażarka typu side by side (5 000 PLN)
- inkubator mikrobiologiczny o dużej pojemności(ok. 700-750 L) z możliwością sterylizacji i systemem monitorującym temperaturę (43 000 PLN)
- Nano Drop Lite (37 000 PLN)
- serwer do analiz danych z RNAseq (28 000 PLN)
- wirówka stołowa z chłodzeniem (23 500 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Mycobacterium tuberculosis binds human serum amyloid A, and the interaction modulates the colonization of human macrophages and the transcriptional response of the pathogenAuthors:Malwina Kawka, Anna Brzostek, Katarzyna Dzitko, Jakub Kryczka, Radosław Bednarek, Renata Płocińska, Przemysław Płociński, Dominik Strapagiel, Justyna Gatkowska, Jarosław Dziadek , Bożena Dziadek (autor korespondujący)Academic press:Cells (rok: 2021, tom: May 20;10(5), strony: brak), Wydawca: MDPIStatus:PublishedDOI:10.3390/cells10051264 - link to the publication
- The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infectionAuthors:Malwina Kawka, Renata Płocińska, Przemysław Płociński, Jakub Pawełczyk, Marcin Słomka, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek, Jarosław DziadekAcademic press:Frontiers in Immunology (rok: 2023, tom: 14, strony: brak), Wydawca: FrontiersStatus:PublishedDOI:10.3389/fimmu.2023.1238132 - link to the publication