Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Peroxiredoxins as potential therapeutic targets in glioblastoma.

2017/25/B/NZ7/00388

Keywords:

glioblastoma peroxiredoxins therapeutic targets

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Monika Szeliga 

Number of co-investigators in the project: 3

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 602 700 PLN

Project start date (Y-m-d): 2018-01-19

Project end date (Y-m-d): 2023-01-18

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Inkubator CO2 (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Conoidin A, a covalent inhibitor of peroxiredoxin 2, reduces growth of glioblastoma cells by triggering ROS production.
    Authors:
    Szeliga M., Rola R.
    Academic press:
    Cells (rok: 2023, tom: 12, strony: 1934), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/cells12151934. - link to the publication
  2. Comprehensive analysis of the expression levels and prognostic values of PRDX family genes in glioma.
    Authors:
    Szeliga M.
    Academic press:
    Neurochemistry International (rok: 2022, tom: 153, strony: 105256), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuint.2021.105256 - link to the publication
  3. Menadione potentiates auranofin-induced glioblastoma cell death.
    Authors:
    Szeliga M., Rola R.
    Academic press:
    Int J Mol Sci. (rok: 2022, tom: 23, strony: 15712), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/ijms232415712. - link to the publication

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