Projects funded by the NCN

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102 projects found matching your search criteria :

  1. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  2. Drug repurposing to target p53 protein family for improved therapy in the relapsed TP53 and EGFR mutated lung cancer

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Joanna Zawacka-Pankau

    Warszawski Uniwersytet Medyczny

  3. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  4. Homo- and heterometallic phosphine ruthenium and iridium complexes - design, synthesis, bioactivity and magnetic-nanofor...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Sandra Kozieł

    Uniwersytet Wrocławski, Wydział Chemii

  5. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  6. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  7. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Mika

    Instytut Farmakologii PAN

  8. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Alicja Gawalska

    Uniwersytet Jagielloński, Collegium Medicum

  9. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. Synthetic analogues of opioid growth factor linked to derivatives of glucosamine as a potential compounds for targeted t...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Iwona Inkielewicz-Stępniak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  11. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  12. Lactoferrin and versatile polymers as a tool for selective and targeted delivery of anticancer hydrophobic drugs in the ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Przemysław Gajda-Morszewski

    Uniwersytet Jagielloński, Wydział Chemii

  13. Dual-targeted biodegradable polymeric micelles for anticancer drug delivery

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr Katarzyna Jelonek

    Centrum Materiałów Polimerowych i Węglowych Polskiej Akademii Nauk

  14. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Aneta Rogalska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  15. Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Tomasz Urbaniak

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  16. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr hab. Artur Wnorowski

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  17. Atomization of liquids for targeted drug delivery to the respiratory system - mechanisms of droplets formation, transpor...

    Call: OPUS 15 , Panel: ST8

    Principal investigator: prof. Tomasz Sosnowski

    Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

  18. Application of targeted metabolomic approach in quantitative prospective analysis of nucleosides profiles alterations be...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: Małgorzata Artymowicz

    Gdański Uniwersytet Medyczny, Wydział Farmacutyczny

  19. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  21. Nanostructured lipidic liquid-crystalline carriers for chemotherapeutics and corpuscular radiation emitters in targeted ...

    Call: OPUS 13 , Panel: ST4

    Principal investigator: dr Ewa Nazaruk

    Uniwersytet Warszawski, Wydział Chemii

  22. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  23. Determination of arginase-1 as a potential drug target in the treatment of multiple myeloma and in reducing proteasome i...

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Jakub Gołąb

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  24. Peroxiredoxins as potential therapeutic targets in glioblastoma.

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Monika Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  25. Exosome biosensors - new tools in cancer screening, diagnostics and development of targeted drug delivery system

    Call: OPUS 13 , Panel: ST4

    Principal investigator: dr hab. Magdalena Stobiecka

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  26. Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Gobis

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  27. Model of lipid nanoagregates transport by epitelial cells with additional steps of pharmacokinetic

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: Kamila Szostak

    Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

  28. Chemical effects in targeted drug delivery: The roles of anticancer drugs, carriers and conjugates on biomimetic membran...

    Call: SONATA 12 , Panel: ST4

    Principal investigator: dr Dorota Nieciecka

    Uniwersytet Warszawski, Wydział Chemii

  29. In vitro studies of NaA nanozeolite functionalized with integrins inhibitor- cilengitide and labeled with radium radioiz...

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr Sylwia Męczyńska-Wielgosz

    Instytut Chemii i Techniki Jądrowej

  30. Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Katarzyna Malarz

    Uniwersytet Śląski w Katowicach, Wydział Matematyki, Fizyki i Chemii

  31. Inhibitors of anti-apoptotic proteins from the BCL-2 family as agents enhancing BRAFV600E inhibition in melanoma cells.

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr Mariusz Hartman

    Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej

  32. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Michał Załuski

    Uniwersytet Jagielloński, Collegium Medicum, Wydział Farmaceutyczny

  33. Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Bożena Dziadek

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  34. Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  35. Hyphenated separation techniques in the study of the molecular mechanisms of metabolic biotransformation of drugs for ta...

    Call: SONATA 12 , Panel: ST4

    Principal investigator: dr Małgorzata Szultka-Młyńska

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  36. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  38. Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Marek Bajda

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  39. Nanomolecular antioxidants: biological basis of targeted therapy of neurodegenerative diseases.

    Call: SONATA BIS 6 , Panel: NZ7

    Principal investigator: dr hab. Izabela Sadowska-Bartosz

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  40. Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Marta Orlikowska

    Uniwersytet Gdański, Wydział Chemii

  41. Long non-coding RNAs (lncRNA) as treatment efficacy markers in patients with advanced melanoma harboring BRAF mutation.

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Jacek Mackiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

  42. New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krzysztof Walczak

    Politechnika Śląska, Wydział Chemiczny

  43. Liposomal theranostic agent for magnetic resonance imaging and photodynamic therapy

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Paulina Skupin-Mrugalska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  44. Supramolecular compounds and their complexes with carbon nanotubes as potential systems for targeted delivery of drugs

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Anna Jagusiak

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

  45. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Malawska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  46. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Joanna Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. INNOvative antiSEPTic agents for a therapy with a broad spectrum of action

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr Sebastian Kraszewski

    Politechnika Wrocławska

  48. In vitro and in vivo preclinical studies of NaA nanozeolite functionalized with antibodies anti-PSMA and labeled with ra...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Anna Lankoff

    Instytut Chemii i Techniki Jądrowej

  49. Polymer-based nanostructures modified with biologically active substances for selective accumulation and release of drug...

    Call: PRELUDIUM 10 , Panel: ST5

    Principal investigator: Wioletta Liwińska

    Uniwersytet Warszawski, Wydział Chemii

  50. Investigation of meluclar mechanism of new cell-based, targeted delivery method of anticancer drugs to the tumour tissue

    Call: SONATA BIS 5 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Król

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Medycyny Weterynaryjnej

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