Projects funded by the NCN

The role of a SNAIL1 transcription factor in the pathogenesis of non-epithelial tumors.

Call: OPUS 5 , Panel: NZ5

Principal investigator: prof. Marcin Marek Majka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Analysis of YAP1 gene function as a potential oncogene of renal cell carcinoma based on clinical material and cell lines...

Call: OPUS 3 , Panel: NZ4

Principal investigator: prof. Zbigniew Kmieć

Gdański Uniwersytet Medyczny, Wydział Lekarski

IDENTIFICATION OF NEW CANCER-RELATED GENES THAT PLAY AN IMPORTANT ROLE IN COMMON HUMAN CANCERS

Call: OPUS 1 , Panel: NZ5

Principal investigator: dr hab. Piotr Kozłowski

Politechnika Poznańska, Wydział Informatyki

"Silencing and functional analysis of selected genes potentially involved in the pathogenesis of the laryngeal squamous ...

Call: PRELUDIUM 3 , Panel: NZ1

Principal investigator: Magdalena Kostrzewska-Poczekaj

Instytut Genetyki Człowieka PAN

PIM kinases as rational therapeutic targets in lymphoid malignancies.

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

Call: SONATA BIS 14 , Panel: NZ3

Principal investigator: dr Jan Marian Suski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Clonal and epigenetic pathways in the development of pediatric acute lymphoblastic leukemia.

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Jadwiga Maria Filipek-Gorzała

Uniwersytet Jagielloński

Deciphering the importance of the intracellular FGFR1 module for cell fate

Call: OPUS 26 , Panel: NZ1

Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

Uniwersytet Wrocławski, Wydział Biotechnologii

The mechanism of competition of mutant p53 gain-of-function and major oncogene CMYC in gastric cancer.

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Marcin Mikołaj Grochowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Oncogene competition - a new interplay mechanism of mutant p53 with CMYC and mutant KRAS in human cancers.

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Dawid Włodzimierz Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identification and therapeutic targeting of the mRNA splicing alteration mechanisms driven by gain-of-function TP53 muta...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Magdalena Oroń

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Natalia Maćkowska-Maślak

Instytut Genetyki Człowieka PAN

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

The influence of EGFRvIII structure and its cellular distribution heterogeneity on designing new therapeutic and diagnos...

Call: OPUS 18 , Panel: NZ3

Principal investigator: prof. Piotr Rieske

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Spatial network model of sequence and structure diversity of Human genome at a population scale

Call: PRELUDIUM BIS 1 , Panel: ST6

Principal investigator: prof. Dariusz Michał Plewczyński

Politechnika Warszawska, Wydział Matematyki i Nauk Informacyjnych

Mechanisms of transcriptional repression by Gli proteins in Hedgehog signaling

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Paweł Niewiadomski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Studies of the molecular mechanisms associated with HPV and CMV infections involved in the pathogenesis of ovarian cance...

Call: OPUS 17 , Panel: NZ7

Principal investigator: dr hab. Edyta Teresa Paradowska

Instytut Biologii Medycznej PAN

Multi-onco-map: a multi-omic map of the major driver oncogene function in cancer

Call: SONATA BIS 7 , Panel: NZ5

Principal investigator: dr Dawid Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identification of novel oncogenic/tumor suppressive miRNA-mRNA interactions in pathogenesis of pediatric T-cell acute ly...

Call: PRELUDIUM 13 , Panel: NZ2

Principal investigator: Monika Drobna-Śledzińska

Instytut Genetyki Człowieka PAN

Structural studies on inhibition mechanisms of enzymes belonging to USP family, which remove ubiquitin from eukaryotic p...

Call: SONATINA 1 , Panel: NZ1

Principal investigator: dr Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Chemii

A molecular analysis of the CRNDE gene and an attempt to assess the function and clinical significance of the newly disc...

Call: SONATA 12 , Panel: NZ5

Principal investigator: dr Łukasz Michał Szafron

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Bayesian analysis of bladder cancer subtypes based on high-throughput data

Call: PRELUDIUM 11 , Panel: ST6

Principal investigator: Krzysztof Kamil Gogolewski

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Mitotic catastrophe and amplicon loss as a basis of negative selection of glioblastoma cells with oncogene amplicons

Call: SONATA 11 , Panel: NZ3

Principal investigator: dr hab. Ewelina Stoczyńska-Fidelus

Uniwersytet Medyczny w Łodzi, Wydział Lekarski; Oddział Nauk Biomedycznych

Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

Call: SONATA 11 , Panel: NZ5

Principal investigator: dr Bartosz Puła

Instytut Hematologii i Transfuzjologii

Role of miR-299-5p in pathogenesis of laryngeal squamous cell carcinoma.

Call: PRELUDIUM 11 , Panel: NZ5

Principal investigator: Joanna Janiszewska

Instytut Genetyki Człowieka PAN