Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

163 projects found matching your search criteria :

  1. Czy hiperaktywacja kinazy mTOR prowadzi do zaburzeń różnicowania komórek nerwowych?

    Call: FUGA 1 , Panel: NZ3

    Principal investigator: dr Bartosz Tarkowski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  2. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  3. PIM kinases as rational therapeutic targets in lymphoid malignancies.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  4. The role of SnRK2 kinases in plant response to environmental stresses. The interplay between SnRK2 kinases, PP2C phospha...

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Grażyna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  5. Investigation of histidine phosphorylation in thymidylate synthase and searching for causative protein kinase

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: dr hab. Joanna Cieśla

    POLITECHNIKA WARSZAWSKA

  6. Regulation of clathrin-dependent endocytosis by mTOR kinase in neuronal development

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Jacek Jaworski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  7. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  8. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  9. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  10. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  11. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Paweł Kochanowski

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  12. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  13. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  14. The effect of PKC epsilon modification on autophagy in cancer cells.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Maria Rybczyńska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  15. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  16. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in...

    Call: POLONEZ BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Aneta Radziwon-Balicka

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  17. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  18. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Sławomir Kasperowicz

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  19. Smart tissue engineering to change the paradigm of diabetes treatment

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  20. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Sumara

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  21. The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi...

    Call: OPUS 23 , Panel: NZ3

    Principal investigator: dr Anna Kulik

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  22. Jasmonic acid biosynthesis enviromental regulation through mitogen-activated protein kinases in Arabidopsis thaliana.

    Call: SONATA 1 , Panel: NZ3

    Principal investigator: dr Łukasz Gałgański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  23. Analysis of molecular background of clear cell renal cell carcinoma and role of MCPIP1 in tomorigenesis

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Jolanta Jura

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  24. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Szydłowski

    Instytut Hematologii i Transfuzjologii

  25. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  26. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Majsterek

    Uniwersytet Medyczny w Łodzi

  27. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Florczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  28. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  29. Investigation of the MLK4 biology in breast cancer and search for new therapeutic strategies using innovative PROTAC com...

    Call: SONATA BIS 11 , Panel: NZ5

    Principal investigator: dr Anna Marusiak

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  30. RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Mikołaj Czajkowski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  31. Expression, regulation and function of super-enhancer non-coding RNAs in Diffuse Large B-Cell Lymphoma (DLBCL)

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Sonia Dębek

    Instytut Hematologii i Transfuzjologii

  32. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Wilczkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. MLK4 signaling in DNA damage response and cancer therapy

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: Dawid Mehlich

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  34. AXL receptor signaling in cancer cell growth and drug resistance

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: prof. Marta Miączyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  35. Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Anna Mrozek-Wilczkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  36. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  37. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  38. FAST interactions in cell death regulation

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Daria Dawidziak

    Uniwersytet Warszawski, Wydział Chemii

  39. OMENTIN1 as a new regulator of female reproduction - expression and role in the pituitary - ovary axis. Study on swine m...

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr hab. Agnieszka Rak

    Uniwersytet Jagielloński, Wydział Biologii

  40. Towards innovative strategy for treatment of Alzheimer's Disease via dual inhibition of receptor 5-HT6 and kinase CDK5.

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Sylwia Sudoł

    Uniwersytet Jagielloński, Collegium Medicum

  41. The proangiogenic functions of PIM kinases in plasma cell myeloma

    Call: ETIUDA 8 , Panel: NZ5

    Principal investigator: Filip Garbicz

    Instytut Hematologii i Transfuzjologii

  42. New insights into multifaceted targeted therapy for treatment of glioblastoma multiforme.

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Katarzyna Malarz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  43. Determination of the role of present in extracelluar space integrin-linked kinase (ILK) in adhesion, migration/invasion ...

    Call: PRELUDIUM BIS 1 , Panel: NZ3

    Principal investigator: dr hab. Antonina Mazur

    Uniwersytet Wrocławski, Wydział Biotechnologii

  44. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Karaś

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  45. Comprehensive bioinformatic analysis of known and novel human microbiome kinases and pseudokinases.

    Call: PRELUDIUM 18 , Panel: NZ2

    Principal investigator: Marcin Gradowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  46. Role of heteromultimerization of MRCK kinases in physiological and pathological processes.

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Brygida Baran

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  47. Restoration of beta-cell function via inhibition of diabetic kinome.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński

  48. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Aneta Rogalska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  49. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  50. Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic pot...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr Dariusz Pytel

    Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej