Projects funded by the NCN


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163 projects found matching your search criteria :

  1. Role of heteromultimerization of MRCK kinases in physiological and pathological processes.

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Brygida Karolina Baran

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  2. Restoration of beta-cell function via inhibition of diabetic kinome.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński

  3. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Aneta Katarzyna Rogalska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  4. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  5. Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic pot...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr Dariusz Maciej Pytel

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  6. Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

    Call: PRELUDIUM 17 , Panel: NZ5

    Principal investigator: Brygida Elżbieta Marczyk

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  7. Identification of group I SnRK2s substrates involved in RNA metabolism and elucidation the role of their phosphorylation

    Call: PRELUDIUM 17 , Panel: NZ3

    Principal investigator: Adrian Mateusz Kasztelan

    Instytut Biochemii i Biofizyki PAN

  8. DEVELOPMENT OF NEW CLASS PHOTOACTIVATED ANTICANCER-ANTIFUNGAL COMPOUNDS: CONJUGATES OF GOLD NANOPARTICLE-SUPPORTED QUINO...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Oleh M. Demchuk

    Katolicki Uniwersytet Lubelski Jana Pawła II, Wydział Medyczny

  9. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  10. The role of PIM kinases in the vascular niche of multiple myeloma

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Filip Aleksander Garbicz

    Instytut Hematologii i Transfuzjologii

  11. Evaluation of the impact of exercise / stress stimuli on the mechanisms and efficacy of beta-hydroxy-beta-methylbutyric ...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Krzysztof Durkalec-Michalski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

  12. Engagement of RIPK4 in RAF1/MEK/ERK pathway in melanoma cells.

    Call: PRELUDIUM 16 , Panel: NZ3

    Principal investigator: dr Ewelina Karolina Madej

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  13. Structure and function of a unique two-component system of periodontopathogenic bacteria Porphyromonas gingivalis

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  14. Regulation of carnitine transporters secretory pathway by AKT - a kinase hyperactivated in cancer cells

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: prof. Katarzyna Anna Nałęcz

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  15. Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

    Call: SONATA BIS 8 , Panel: NZ2

    Principal investigator: dr hab. Michał Marek Mikula

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  16. Role of histone H3 serine 10 (H3S10) kinases in deregulation of transcription in diffuse large B-cell lymphoma

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  17. Modeling phosphorylation by human thymidine kinase 1. A crucial step in the rational design of thymidine-analogue radios...

    Call: PRELUDIUM 15 , Panel: ST4

    Principal investigator: dr Samanta Kinga Romanowska

    Uniwersytet Gdański, Wydział Chemii

  18. The role of sphingosine kinases/sphingosine-1-phosphate dependent signaling in mice brains exposed to type II diabetes m...

    Call: PRELUDIUM 15 , Panel: NZ4

    Principal investigator: dr Przemysław Leonard Wencel

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  19. Role of the lysosomes in insulin-dependent regulation of AMP-ativated protein kinase expression and activity in podocyte...

    Call: PRELUDIUM 15 , Panel: NZ4

    Principal investigator: Patrycja Rachubik

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  20. Integrating light and osmotic stress signaling- molecular functions of Plastid Movement Impaired 1 protein from Arabidop...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: dr Olga Sztatelman

    Instytut Biochemii i Biofizyki PAN

  21. The new role of chloroplasts and PsbS-dependent non-photochemical quenching of absorbed energy and LSD1 regulon in retro...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: prof. Stanisław Mariusz Karpiński

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  22. The role of diacylglycerol kinase epsilon, an enzyme of the phosphatidylinositol cycle, in the regulation of LPS-induced...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: prof. Katarzyna Kwiatkowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  23. Functional significance of interaction of unconventional myosin VI with the AKAP9-PKA complex: Potential novel regulator...

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: prof. Maria Jolanta Rędowicz

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  24. The role of glycogen synthase kinase 3 (GSK-3) in activation p53 and the TREM2 signaling pathway

    Call: PRELUDIUM 14 , Panel: NZ5

    Principal investigator: dr Barbara Małgorzata Łasut-Szyszka

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

  25. SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr Anna Marta Kulik

    Instytut Biochemii i Biofizyki PAN

  26. Role of PIM kinases in the biology of classical Hodgkin lymphoma tumor-associated macrophages

    Call: SONATA 13 , Panel: NZ5

    Principal investigator: dr Maciej Stefan Szydłowski

    Instytut Hematologii i Transfuzjologii

  27. The influence of impairment of extracellular nucleoside and nucleotide signaling on synaptic structure and function in a...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: dr hab. Agata Adamczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  28. How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the s...

    Call: OPUS 13 , Panel: NZ3

    Principal investigator: dr Aneta Edyta Kaniak-Golik

    Instytut Biochemii i Biofizyki PAN

  29. Role of a protein kinase-like effector HopBF1 in virulence of bacterial pathogens.

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: dr hab. Magdalena Krzymowska

    Instytut Biochemii i Biofizyki PAN

  30. Design of new small molecular regulators (inhibitors, activators) of the catalytic activity of adenylate kinases. Molecu...

    Call: OPUS 13 , Panel: ST4

    Principal investigator: dr Anna Kozakiewicz-Piekarz

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  31. Anaplastic Lymphoma Kinase (ALK) Overexpression as a Prognostic and Predictive Factor in Serous Ovarian Carcinoma

    Call: PRELUDIUM 13 , Panel: NZ4

    Principal investigator: Adam Stanisław Gorczyński

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  32. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Agata Zygmunt

    Instytut Farmakologii PAN

  33. Estrogen dependent signal transduction associated with PELP1 protein in male reproductive system

    Call: SONATA 12 , Panel: NZ5

    Principal investigator: dr Izabela Skibińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Nauk o Zdrowiu

  34. Protein kinase B signalling pathway in glioblastoma cells transfected with sequence encoding liver-type glutaminase (GAB...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Ewelina Julia Majewska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  35. Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Katarzyna Anna Malarz

    UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

  36. The role of SnRK2 kinases in regulation of pre-mRNA alternative splicing and miRNA biogenesis in plants response to sali...

    Call: OPUS 12 , Panel: NZ3

    Principal investigator: dr hab. Grażyna Anna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  37. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the colorectal cancer treatment

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Adam Janusz Dziki

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  38. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response ...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Paweł Burdiak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  39. Evaluation of the impact of sphingosine kinase type 1 and 2 activity on the pharmacological mobilization of hematopoieti...

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Mateusz Stanisław Adamiak

    Warszawski Uniwersytet Medyczny, II Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim oraz Oddziałem Fizjoterapii

  40. Sphingosine kinase 1 as a modulator of vascular function - mechanisms and therapeutical opportunities

    Call: SONATA BIS 6 , Panel: NZ4

    Principal investigator: dr hab. Mateusz Siedliński

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  41. Impact of palmitoylation on the Zn(II)-dependent interaction between CD4 coreceptor and Lck tyrosine kinase.

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  42. Analysis of the effectiveness of anticancer activity of tyrosine kinase inhibitors combined with nanoparticles in in vit...

    Call: SONATA 11 , Panel: ST4

    Principal investigator: dr Natalia Piergies

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

  43. ADAM17 as a key protein in cellular response to proinflammatory mediators

    Call: OPUS 11 , Panel: NZ3

    Principal investigator: prof. Joanna Katarzyna Bereta

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  44. mTOR kinase impact on cellular functions of selected molecular motors

    Call: OPUS 11 , Panel: NZ3

    Principal investigator: prof. Jacek Ryszard Jaworski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  45. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the primary open-angle glaucoma treatmen...

    Call: OPUS 11 , Panel: NZ5

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  46. Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Bartosz Puła

    Instytut Hematologii i Transfuzjologii

  47. New opportunities for use of PERK kinase inhibitors in eIF2alfa factor-dependant signalling pathway in antitumor therapy

    Call: PRELUDIUM 10 , Panel: NZ3

    Principal investigator: dr Wioletta Julia Rozpędek-Kamińska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  48. SOD1 superoxide dismutase regulation in stomatal closure signalling in A. thaliana.

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Hanna Maria Gałgańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  49. Mitochondrial nucleoside diphosphate kinase (NDPK) as a regulator of mitochondrial proton leak catalyzed by purine nucle...

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Andrzej Marek Woyda-Płoszczyca

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  50. Endocytosis of AXL receptor and its role in AXL-mediated signaling.

    Call: SONATA 10 , Panel: NZ3

    Principal investigator: dr Daria Paulina Zdżalik-Bielecka

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej