Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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mTOR kinase impact on cellular functions of selected molecular motors

2016/21/B/NZ3/03639

Keywords:

molecular motors cellular transport mTOR neurons and neuroprogenitors

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Jaworski 

Number of co-investigators in the project: 6

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 336 250 PLN

Project start date (Y-m-d): 2017-03-01

Project end date (Y-m-d): 2021-02-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. Role of dynein-dynactin complex, kinesins, motor adaptors, and their phosphorylation in dendritogenesis
    Authors:
    Aleksandra Tempes, Jan Weslawski, Agnieszka Brzozowska, Jacek Jaworski
    Academic press:
    Journal of Neurochemistry (rok: 2020, tom: 155, strony: 45958), Wydawca: John Wiley & Sons, Inc.
    Status:
    Published
    DOI:
    10.1111/jnc.15010 - link to the publication
  2. Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner
    Authors:
    Janusz-Kaminska A, Brzozowska A, Tempes A, Urbanska M, Blazejczyk M, Miłek J, Kuzniewska B, Zeng J, Wesławski J, Kisielewska K, Bassell GJ, Jaworski J.
    Academic press:
    Mol Biol Cell. (rok: 2024, tom: 35, strony: ar43, 1-20), Wydawca: The American Society of Cell Biology
    Status:
    Published
    DOI:
    10.1091/mbc.E23-02-0060. - link to the publication
  3. Autophagy initiation triggers p150Glued-AP-2β interaction on the lysosomes and facilitates their transport
    Authors:
    Tempes A, Bogusz K, Brzozowska A, Weslawski J, Macias M, Tkaczyk O, Orzoł K, Lew A, Calka-Kresa M, Bernas T, Szczepankiewicz AA, Mlostek M, Kumari S, Liszewska E, Machnicka K, Bakun M, Rubel T, Malik AR, Jaworski J.
    Academic press:
    Cell Mol Life Sci. (rok: 2024, tom: 81(1), strony: 218:1-25), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-024-05256-6 - link to the publication
  1. Neural Stem Cell Dysfunction in Human Brain Disorders
    Authors:
    Ewa Liszewska, Jacek Jaworski
    Book:
    Human Neural Stem Cells From Generation to Differentiation and Application (rok: 2018, tom: 1, strony: 283-299), Wydawca: Springer
    Status:
    Published

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