How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the stability of mitochindrial genome: a study on the yeast model of mutations in polymerase POLG.

2017/25/B/NZ3/01811

Keywords

Descriptors

  • NZ1_10: Biologia drobnoustrojów
  • NZ1_1: Biologia molekularna
  • NZ3_1: Biologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Aneta Edyta Kaniak-Golik

Number of co-investigators in the project: 4

Call

OPUS 13 – announced on 2017-03-15

Amount awarded
818 000 PLN
Project start date
2018-01-09
Project end date
2023-01-08
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. PCNA and Rnh1 independently participate in the protection of mitochondrial genome against UV-induced mutagenesis in yeast cells

    Authors:
    Martyna Latoszek, Katarzyna Baginska-Drabiuk, Ewa Sledziewska-Gojska, Aneta Kaniak-Golik
    Academic press:
    Scientific Reports (year: 2024, volume: 14, pages: 31017), Publisher: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-024-82104-4 – link to the publication
  2. The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus

    Authors:
    Damian Kolakowski, Weronika Rzepnikowska, Aneta Kaniak-Golik, Teresa Zoladek, Joanna Kaminska
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 12274), Publisher: Basel, Switzerland : MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212274 – link to the publication
  3. Developmental delay with hypotrophy associated with homozygous functionally relevant REV3L variant

    Authors:
    Halas A, Fijak-Moskal J, Kuberska R, Murcia Pienkowski V, Kaniak-Golik A, Pollak A, Poznanski J, Rydzanicz M, Bik-Multanowski M, Sledziewska-Gojska E, Płoski R.
    Academic press:
    Journal of Molecular Medicine (year: 2021, volume: 99(3), pages: 415-423), Publisher: Berlin : Springer International
    Status:
    Published
    DOI:
    10.1007/s00109-020-02033-3 – link to the publication

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