Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evaluation of the impact of sphingosine kinase type 1 and 2 activity on the pharmacological mobilization of hematopoietic stem/progenitor cells.

2016/23/N/NZ4/03345

Keywords:

mobilization hematopoietic stem/progenitor cells sphingosine kinase sphingosine-1-phosphate

Descriptors:

  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Warszawski Uniwersytet Medyczny, II Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim oraz Oddziałem Fizjoterapii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Mateusz Adamiak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 99 600 PLN

Project start date (Y-m-d): 2017-07-12

Project end date (Y-m-d): 2019-11-11

Project duration:: 28 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells
    Authors:
    Mateusz Adamiak, Lakshman Chelvarajan, Kevin R. Lynch, Webster L. Santos, Ahmed Abdel-Latif, Mariusz Z. Ratajczak
    Academic press:
    Oncotarget (rok: 2017, tom: 8, strony: 65588-65600), Wydawca: Impact Journals, LLC
    Status:
    Published
    DOI:
    10.18632/oncotarget.19514 - link to the publication
  1. UDZIAŁ SFINGOZYNO-1-FOSFORANU WE WSZCZEPIENIU I ZASIEDLANIU NISZY SZPIKOWEJ PRZEZ KRWIOTWÓRCZE KOMÓRKI MACIERZYSTE
    Authors:
    Mateusz Adamiak, Sylwia Borkowska, Marcin Wysoczyński, Malwina Suszyńska, Magdalena Kucia, Ahmed Abdel-Latif, Janina Ratajczak, Mariusz Z. Ratajczak
    Conference:
    XXVII Zjazd Polskiego Towarzystwa Hematologów i Transfuzjologów (rok: 2017, ), Wydawca: Acta Haematologica Polonica
    Data:
    konferencja 21-23.09
    Status:
    Published
  2. Impact of sphingosine kinase 2 (SphK2) deficiency on the level of Sphingosine-1-phosphate (S1P) in peripheral bloodand hematopoietic stem cell mobilization activity.
    Authors:
    Mateusz Adamiak, Lakshman Chelvarajan, Kevin R. Lynch, Webster L. Santos, Ahmed Abdel-Latif, Mariusz Z. Ratajczak
    Conference:
    4th Baltic Stem Cell Meeting (rok: 2018, ), Wydawca: Wydawnictwo Warszawskiego Uniwersytetu Medycznego
    Data:
    konferencja 28-30.09
    Status:
    Published