Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

55 projects found matching your search criteria :

  1. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Tomasz Bączek

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  2. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  3. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Paweł Zajdel

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  5. Dual action of HBK-15 – unraveling cellular mechanisms underlying its fast antidepressant-like and procognitive effects...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Karolina Anna Pytka

    Uniwersytet Jagielloński, Collegium Medicum

  6. The influence of microplastics on the toxicity and fate of selected antidepressants

    Call: OPUS 18 , Panel: NZ8

    Principal investigator: prof. Grzegorz Leszek Nałęcz-Jawecki

    Warszawski Uniwersytet Medyczny

  7. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

    Call: OPUS 22 , Panel: HS6

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. The role of GPR39 receptor in the mechanism of antidepressant action

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Katarzyna Młyniec

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  10. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Bartłomiej Pochwat

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. The role of inflammation, oxidative and nitrosative stress, tryptophan catabolites pathway and DNA base excision repair ...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  14. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Agata Faron-Górecka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Effect of modulation of the GPR39 zinc receptor on glutamatergic and gabaergic transmission in the context of antidepres...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Gabriela Starowicz

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  17. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Zofia Rogóż

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Justyna Brodowicz

    Instytut Farmakologii Polskiej Akademii Nauk

  19. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: dr Agnieszka Jankowska

    Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  20. Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt...

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Przemysław Taciak

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  21. The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  22. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Trojan

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. Impact of pharmacogenetic profiles on depression treatment outcomes

    Call: SONATINA 5 , Panel: NZ2

    Principal investigator: dr Małgorzata Maria Borczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Anti-neuroinflammatory and antidepressant activities of mycelial in vitro cultures of selected edible mushrooms enriched...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Jan Lazur

    Uniwersytet Jagielloński w Krakowie

  25. Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Karolina Pytka

    Uniwersytet Jagielloński w Krakowie

  26. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Rafało-Ulińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Novel pharmacological strategies for the treatment of depression

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Młyniec

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  28. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Sowa-Kućma

    Instytut Farmakologii PAN

  29. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Kamińska

    Instytut Farmakologii PAN

  30. Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  31. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr Andrzej Chodkowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  32. Metabolic stability and inhibition of P450 enzymes in combination with chemometric techniques as a tool for selection of...

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Tomasz Bączek

    Gdański Uniwersytet Medyczny, Wydział Farmcautyczny z Oddziałem Medycyny Laboratoryjnej

  33. Electrochemical detection of phycotropic substances based on DNA intercalation

    Call: PRELUDIUM 4 , Panel: ST4

    Principal investigator: dr Joanna Jankowska-Śliwińska

    Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

  34. Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Maciej Pawłowski

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  35. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Maciej Kuśmider

    Instytut Farmakologii PAN

  36. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. 3D printing as a tool to obtain transdermal microneedle systems with improved efficiency in the treatment of depressive ...

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Zbigniew Osmałek

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  38. The role of the immune checkpoints in the pathomechanism of depressive disorders.

    Call: OPUS 22 , Panel: NZ6

    Principal investigator: prof. Marta Wanda Kubera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  39. Selected antidepressants toxicity assessment based on in vitro studies of rat spermatocytes and mouse cell lines.

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Przemysław Sołek

    Uniwersytet Rzeszowski, Wydział Biotechnologii

  40. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Nalepa

    Instytut Farmakologii PAN

  41. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Podkowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Franciszek Herold

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  43. Synthesis, physicochemical and pharmacological properties of new amide derivatives of 3,3-disubstituted pyrrolidine-2,5-...

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Jolanta Obniska

    Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  44. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  45. Evaluation of the role of subpopulations of T lymphocytes (Treg: CD4+CD25+, CD4+CD25- i Teff: Th2) in depression using p...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Sylwia Kędracka-Krok

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  46. Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: prof. Małgorzata Filip

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  47. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

  48. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  49. The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr hab. Mariusz Papp

    Instytut Farmakologii PAN

  50. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy