Selected antidepressants toxicity assessment based on in vitro studies of rat spermatocytes and mouse cell lines.
2014/15/N/NZ7/04097
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- NZ7_15: Toksykologia
- NZ1_1: Biologia molekularna
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Rzeszowski, Wydział Biotechnologii
Voivodeship: podkarpackie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 8 – announced on 2014-09-15
- Amount awarded
- 149 940 PLN
- Project start date
- 2015-07-23
- Project end date
- 2019-07-22
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (4)
-
Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies
- Authors:
- Przemyslaw Solek, Oliwia Koszla, Jennifer Mytych, Joanna Badura, Zaneta Chelminiak, Magdalena Cuprys, Joanna Fraczek, Anna Tabecka-Lonczynska, Marek Koziorowski
- Academic press:
- Apoptosis (year: 2019, volume: 24, pages: 773-784), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s10495-019-01557-5 – link to the publication
-
Klotho-mediated changes in shelterin complex promote cytotoxic autophagy and apoptosis in amitriptyline-treated hippocampal neuronal cells
- Authors:
- Jennifer Mytych, Przemyslaw Solek, Anna Tabecka-Lonczynska, Marek Koziorowski
- Academic press:
- Molecular Neurobiology (year: 2019, volume: 56, pages: 6952-6963), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12035-019-1575-5 – link to the publication
-
Toxic effect of antidepressants on male reproductive system cells: evaluation of possible fertility reduction mechanism
- Authors:
- Przemyslaw Solek, Jennifer Mytych, Anna Tabecka-Lonczynska, Magdalena Sowa-Kucma, Marek Koziorowski
- Status:
- Accepted for publication
-
Molecular consequences of depression treatment: a potential mechanism for antidepressants-induced reprotoxic side effects
- Authors:
- Przemyslaw Solek, Jennifer Mytych, Anna Tabecka-Lonczynska, Marek Koziorowski
- Status:
- Accepted for publication
Articles in post-conference publications (1)
-
OCENA FARMAKOTOKSYCZNYCH WŁAŚCIWOŚCI LEKÓW PRZECIWDEPRESYJNYCH W UKŁADZIE IN VITRO KOMÓREK MYSICH NEURONÓW HIPOKAMPA (HT-22)
- Authors:
- Oliwia Koszla, Joanna Badura, Jennifer Mytych, Marek Koziorowski, Przemyslaw Solek*
- Conference:
- Człowiek – Żywność – Środowisko (year: 2017, pages: 84-94), Publisher: Uniwersytet Rzeszowski
- Date:
- conference 27-28.04
- Status:
- Published