Projects funded by the NCN

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30 projects found matching your search criteria :

  1. Functionalized carbohydrates pharmacophores as a putative antituberculosis drugs - the mechanism of action.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  2. The studies on microevolution markers of Mycobacterium bovis BCG Moreau substrain used for BCG immunization against tube...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Katarzyna Krysztopa-Grzybowska

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

  3. Involvement of cholesterol oxidase of Mycobacterium tuberculosis in the modulation of TLR2-dependent signaling pathway i...

    Call: OPUS 8 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Teresa Klink

    Instytut Biologii Medycznej PAN

  4. The role of IL8 in pathogenesis of tubercle bacili.

    Call: HARMONIA 1 , Panel: NZ6

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  5. Implication of orphan response regulatory proteins in the physiology and virulence of Mycobacterium tuberculosis.

    Call: SONATA 6 , Panel: NZ6

    Principal investigator: dr Renata Anna Płocińska

    Instytut Biologii Medycznej PAN

  6. Searching for natural substances with antitubercular activity and their influence on the cell wall synthesis process in ...

    Call: SONATA 6 , Panel: NZ7

    Principal investigator: dr Elwira Zofia Sieniawska

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  7. Identification of the acetyl coenzyme A carboxylation mechanism i pathogenic and nonpathogenic mycobacterial species

    Call: PRELUDIUM 3 , Panel: NZ2

    Principal investigator: dr Jakub Pawełczyk

    Instytut Biologii Medycznej PAN

  8. Inhibitors of the non-mevalonate isoprenoid biosynthesis pathway - a new class of antibiotics against tuberculosis and m...

    Call: SONATA 20 , Panel: ST5

    Principal investigator: dr Ignacy Przemysław Janicki

    Centrum Badań Molekularnych i Makromolekularnych PAN

  9. Demonstration of the key role of vitamin B12 uptake in regulating Mycobacterium tuberculosis virulence lipids synthesis ...

    Call: SONATA BIS 14 , Panel: NZ6

    Principal investigator: dr Jakub Pawełczyk

    Instytut Biologii Medycznej PAN

  10. The Potential of Mycobacterium tuberculosis Phase-Specific Antigens for Targeted TB Diagnosis

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr Shima Mahmoudi

    Politechnika Śląska

  11. Metabolomic comparison of Mycobacterium tuberculosis and Mycobacterium marinum model organisms in response to antimicrob...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Marcin Karol Ziomek

    Uniwersytet Medyczny w Lublinie

  12. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  13. Role of natural products in overcoming drug resistance in Mycobacterium tuberculosis

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Elwira Zofia Sieniawska

    Uniwersytet Medyczny w Lublinie

  14. Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity....

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

    Instytut Biologii Medycznej PAN

  15. Mycobacterium tuberculosis factors affecting the frequency of tuberculosis transmission

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Ewa Maria Augustynowicz-Kopeć

    Instytut Gruźlicy i Chorób Płuc

  16. Structural insights into the involvement of the RNA degradosome in trans-translation in the light of the antimicrobial a...

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Przemysław Adam Płociński

    Uniwersytet Łódzki

  17. The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

    Call: SONATA BIS 9 , Panel: NZ6

    Principal investigator: dr Alina Ewa Minias

    Instytut Biologii Medycznej PAN

  18. Deciphering the role of putative protein factors involved in the mycobacterial DNA strand break repairs

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: dr Przemysław Adam Płociński

    Instytut Biologii Medycznej PAN

  19. Fighting antibiotic-resistant superbugs with anti-persister compounds targeting the strigent response

    Call: UNISONO , Panel: NZ6

    Principal investigator: dr hab. Ewa Laskowska

    Uniwersytet Gdański

  20. Genomic insights into the mechanisms of drug resistance, virulence and transmission of Mycobacterium tuberculosis strain...

    Call: DAINA 1 , Panel: NZ6

    Principal investigator: dr Tomasz Jagielski

    Uniwersytet Warszawski, Wydział Biologii

  21. Understanding the interactions of zinc with metal-sensing transcriptional regulators from Mycobacterial ArsR-family

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Sławomir Potocki

    Uniwersytet Wrocławski, Wydział Chemii

  22. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  23. Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Małgorzata Gobis

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  24. Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Bożena Renata Dziadek

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  25. Immune and metabolomic signatures in chidhood Mycobacterium tuberculosis infections

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr Magdalena Ewa Druszczyńska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  26. Theranostics with nanoporous metal-organic frameworks for inhalable therapy of tuberculosis

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Gabriela Małgorzata Wyszogrodzka

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  27. Molecular and functional analysis of interleukin 18 (IL-18) its receptor (IL-18R) and IL-18- binding protein (IL-18BP) i...

    Call: PRELUDIUM 10 , Panel: NZ6

    Principal investigator: Sebastian Wawrocki

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  28. The role of core RNA decay machinery in regulation of metabolism of Mycobacterium tuberculosis

    Call: SONATA 10 , Panel: NZ1

    Principal investigator: dr Przemysław Adam Płociński

    Instytut Biologii Medycznej PAN

  29. RecA independent response of tubercle bacilli to DNA damage

    Call: OPUS 10 , Panel: NZ6

    Principal investigator: dr hab. Anna Brzostek

    Instytut Biologii Medycznej PAN

  30. Vitamin B12 and mycobacterial persistence.

    Call: SONATA 10 , Panel: NZ6

    Principal investigator: dr Alina Ewa Minias

    Instytut Biologii Medycznej PAN

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