Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of IL8 in pathogenesis of tubercle bacili.

2011/01/M/NZ6/01764

Keywords:

tuberculosis pathogenesis interleukine 8 neutrophiles

Descriptors:

  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Biologii Medycznej PAN

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jarosław Dziadek 

Number of co-investigators in the project: 5

Call: HARMONIA 1 - announced on 2011-03-15

Amount awarded: 701 000 PLN

Project start date (Y-m-d): 2011-12-08

Project end date (Y-m-d): 2015-09-07

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Autoklaw (15 000 PLN)
  2. Wirówka preparatywna i przystosowanie mikroskopu do pracy we fluorescencji (zgoda Dyrektora NCN na zmianę zaplanowanej do zakupu aparatury badawczej).
  3. Kostkarka do lodu (15 000 PLN)
  4. Wytrząsarka mikrobiologiczna z chłodzeniem (60 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Interaction of lectin pathway of complement-activating pattern recognition molecules with Mycobacteria.
    Authors:
    Bartlomiejczyk MA, Swierzko AS, Brzostek A, Dziadek J, Cedzynski M.
    Academic press:
    Clin Exp Immunol. (rok: 2014, tom: 178(2):, strony: 310-9.), Wydawca: British Society for Immunology
    Status:
    Published
    DOI:
    10.1111/cei.12416 - link to the publication
  2. Mycobacterium tuberculosis AtsG (Rv0296c), GlmU (Rv1018c) and SahH (Rv3248c) proteins function as the human IL-8-binding effectors and contribute to pathogen entry into human neutrophils
    Authors:
    Bozena Dziadek, Anna Brzostek, Marcin Grzybowski, Marek Fol, Agnieszka Krupa, Jakub Kryczka, Przemyslaw Plocinski, Anna Kurdowska and Jaroslaw Dziadek
    Academic press:
    PLOS One (rok: 2016, tom: 11(2), strony: PLoS ONE 11(2): e0148030), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0148030 - link to the publication
  3. Binding of CXCL8 / IL-8 to Mycobacterium tuberculosis modulates the innate immune response
    Authors:
    Agnieszka Krupa, Marek Fol, Bozena Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, A. Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David E. Griffith and Anna Kurdowska
    Academic press:
    Mediators of Inflammation (rok: 2015, tom: ID 124762, strony: --), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/124762 - link to the publication
  1. The interaction between host and bacterial proteins may modulate innate immunity response to infection with Mycobacterium tuberculosis.
    Authors:
    A. Krupa, M. Fol, B. Dziadek, J. Dziadek, A. Kurdowska
    Conference:
    International Conference on Clinical Microbiology & Microbial Genomics (rok: 2012, ), Wydawca: OMICS Publishing Group
    Data:
    konferencja Listopad 12-14
    Status:
    Published

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