The role of IL8 in pathogenesis of tubercle bacili.

2011/01/M/NZ6/01764

Keywords

Descriptors

  • NZ6_4: Bakteriologia

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Instytut Biologii Medycznej PAN

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Jarosław Dziadek

Number of co-investigators in the project: 5

Call

HARMONIA 1 – announced on 2011-03-15

Amount awarded
701 000 PLN
Project start date
2011-12-08
Project end date
2015-09-07
Project duration
45 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Autoklaw. Cost: 15 000 PLN
  2. Kostkarka do lodu. Cost: 15 000 PLN
  3. Wirówka preparatywna i przystosowanie mikroskopu do pracy we fluorescencji (zgoda Dyrektora NCN na zmianę zaplanowanej do zakupu aparatury badawczej).
  4. Wytrząsarka mikrobiologiczna z chłodzeniem. Cost: 60 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Interaction of lectin pathway of complement-activating pattern recognition molecules with Mycobacteria.

    Authors:
    Bartlomiejczyk MA, Swierzko AS, Brzostek A, Dziadek J, Cedzynski M.
    Academic press:
    Clin Exp Immunol. (year: 2014, volume: 178(2):, pages: 310-9.), Publisher: British Society for Immunology
    Status:
    Published
    DOI:
    10.1111/cei.12416 – link to the publication
  2. Mycobacterium tuberculosis AtsG (Rv0296c), GlmU (Rv1018c) and SahH (Rv3248c) proteins function as the human IL-8-binding effectors and contribute to pathogen entry into human neutrophils

    Authors:
    Bozena Dziadek, Anna Brzostek, Marcin Grzybowski, Marek Fol, Agnieszka Krupa, Jakub Kryczka, Przemyslaw Plocinski, Anna Kurdowska and Jaroslaw Dziadek
    Academic press:
    PLOS One (year: 2016, volume: 11(2), pages: PLoS ONE 11(2): e0148030), Publisher: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0148030 – link to the publication
  3. Binding of CXCL8 / IL-8 to Mycobacterium tuberculosis modulates the innate immune response

    Authors:
    Agnieszka Krupa, Marek Fol, Bozena Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, A. Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David E. Griffith and Anna Kurdowska
    Academic press:
    Mediators of Inflammation (year: 2015, volume: ID 124762, pages: --), Publisher: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/124762 – link to the publication

Articles in post-conference publications (1)

  1. The interaction between host and bacterial proteins may modulate innate immunity response to infection with Mycobacterium tuberculosis.

    Authors:
    A. Krupa, M. Fol, B. Dziadek, J. Dziadek, A. Kurdowska
    Conference:
    International Conference on Clinical Microbiology & Microbial Genomics (year: 2012, pages: Volume 4, Issue 5, p 102), Publisher: OMICS Publishing Group
    Date:
    conference Listopad 12-14
    Status:
    Published

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