Search results

1. Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: POLS, Panel: NZ4

2. Improving the healing potential of therapeutic proteins by planned, specific modifiactions on the example of bacteriolyt…

Principal investigator: Marek Harhala

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 18, Panel: NZ6

3. In vitro models for therapeutic proteins secretion in avian oviduct epithelial cells.

Principal investigator: dr Katarzyna Stadnicka

Uniwersytet Technologiczno-Przyrodniczy im. Jana i Jędrzeja Śniadeckich w Bydgoszczy, Wydział Hodowli i Biologii Zwierząt

Call: PRELUDIUM 2, Panel: NZ9

4. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie…

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: SONATA 19, Panel: NZ5

5. efFect of nanoscale, three dimensIonal arrangement of proteins on biological and Therapeutic activity (FIT)

Principal investigator: dr Antonina Naskalska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: OPUS 22 (LAP), Panel: NZ1

6. Antibacterial molecules based on bacteriophage proteins and constant antibody fragments with therapeutic potential for t…

Principal investigator: dr Karolina Aleksandra Filik-Matyjaszczyk

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 20, Panel: NZ7

7. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c…

Principal investigator: dr hab. Monika Emilia Marcinkowska

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ7

8. A comprehensive structural and functional analysis of toxic RNA-protein interactions for better understanding and therap…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 28 (LAP), Panel: NZ5

9. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

Principal investigator: prof. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Call: OPUS 21, Panel: NZ2

10. Gankyrin protein as a new potential therapeutic target in multiple myeloma

Principal investigator: dr hab. Irena Misiewicz-Krzemińska

Instytut Hematologii i Transfuzjologii

Call: OPUS 18, Panel: NZ5

11. Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of…

Principal investigator: dr Renata Joanna Grzela

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 17, Panel: NZ1

12. Modulation of fatty acid binding protein 4 and dietary fatty acid intake as a potential therapeutic target in the manage…

Principal investigator: Paula Mosińska

Uniwersytet Medyczny w Łodzi, Wydzial Lekarski

Call: PRELUDIUM 11, Panel: NZ5

13. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap…

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: SONATA BIS 12, Panel: ST4

14. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap…

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: SONATA 17, Panel: NZ7

15. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic …

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

16. Functional characteristics and therapeutic potential of gain-of-function mutations in complement C2 protein.

Principal investigator: dr hab. Marcin Sebastian Okrój

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: HARMONIA 7, Panel: NZ6

17. The evaluation of influence of genes encoding oxytocin (OXT), dopamine (D) and arginine vasopressin (AVP) precursors pro…

Principal investigator: dr hab. Katarzyna Kucharska

Instytut Psychiatrii i Neurologii

Call: OPUS 8, Panel: HS6

18. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

Principal investigator: dr Natalia Anna Skrzypczak

Fundacja Uniwersytetu im. Adama Mickiewicza

Call: SONATINA 9, Panel: ST5

19. Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for …

Principal investigator: dr hab. Monika Bzowska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

Call: OPUS 25, Panel: NZ6

20. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: MAESTRO 12, Panel: NZ3

21. Development of tools for the rational design of peptide therapeutics

Principal investigator: prof. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: OPUS 20, Panel: NZ2

22. Mechanism of splicing of MBNL1 transcript and its implications for potential therapeutic strategies for myotonic dystrop…

Principal investigator: dr Katarzyna Magdalena Taylor

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA 16, Panel: NZ3

23. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

24. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en…

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ1

25. Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic pot…

Principal investigator: dr Dariusz Maciej Pytel

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 17, Panel: NZ5

26. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 17, Panel: NZ7

27. Identifcation of regulatory effects of bacteriophages with therapeutic potential on mammalian cell functions and immunit…

Principal investigator: dr hab. Krystyna Dąbrowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA BIS 1, Panel: NZ6

28. New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an…

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 1, Panel: ST5

29. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi…

Principal investigator: dr Estera Elmira Rintz

Uniwersytet Gdański

Call: OPUS 29, Panel: NZ2

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