Projects funded by the NCN

Dissecting mechanisms of RNA-based Stress Granules formation, their structure and role in the development of Multi-Drug ...

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

The role of neutrophil extracellular traps and mammalian target of rapamycin complex (mTORc) in the ethiopathogenesis of...

Call: OPUS 9 , Panel: NZ6

Principal investigator: prof. Jacek Musiał

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Fragment-based screening using NMR spectroscopy for the identification of chemical probes that interact with non-canonic...

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Katarzyna Kubica

Uniwersytet Jagielloński, Wydział Chemii

Changes in iron metabolism induced by anticancer compounds in in vitro and in vivo

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Jędrzej Antosiewicz

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

The role of AtEAF1 protein in gene expression regulation

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: Weronika Sura

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Physicochemical and structural study on the influence of charged amino acidic residues presence in the sequence in stabi...

Call: SONATA 1 , Panel: ST4

Principal investigator: dr Joanna Makowska

Uniwersytet Gdański, Wydział Chemii

Identification of proteins interacting with p66Shc protein in the mitochondria associated membranes fraction.

Call: SONATA 9 , Panel: NZ1

Principal investigator: dr Magdalena Lebiedzińska-Arciszewska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Do miRNA determine cell fate during unfolded protein response (UPR) ?

Call: OPUS 9 , Panel: NZ3

Principal investigator: dr hab. Rafał Bartoszewski

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Charakterystyka biochemiczna i strukturalna białka zaangażowanego w proces sporulacji - proteinazy YabG.

Call: ETIUDA 3 , Panel: NZ1

Principal investigator: Przemysław Golik

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

2-oxoglutarate dependent oxygenases catalyzing atypical oxidative transformations - structural and mechanistic studies.

Call: OPUS 8 , Panel: NZ1

Principal investigator: prof. Tomasz Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

The structural consequences of lysenin oligomerization- a toxin specifically binding sphingomyelin in lipid rafts

Call: SONATA 8 , Panel: NZ1

Principal investigator: dr Magdalena Kulma

Instytut Biochemii i Biofizyki PAN

Assessment of the state and function of the brain cholinergic system in animal models of Alzheimer-type and frontotempor...

Call: OPUS 8 , Panel: NZ4

Principal investigator: dr hab. Grażyna Niewiadomska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Selective recognition of toxic heteroaromatic amines and N-nitrosamines in protein providing food products

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Włodzimierz Kutner

Instytut Chemii Fizycznej PAN

The CacyBP/SIP protein as a novel regulator of heat shock protein Hsp90

Call: PRELUDIUM 8 , Panel: NZ3

Principal investigator: Agnieszka Góral

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Study of SNAP-25 protein expression, NMR metabolomic analysis and behavioral characteristics in animal models of infanti...

Call: OPUS 8 , Panel: NZ4

Principal investigator: prof. Jerzy Łazarewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Structure prediction of proteins and large protein assemblies guided by low-resolution or/and sparse experimental data.

Call: SONATA 1 , Panel: NZ2

Principal investigator: dr Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Identification of new genetic risk factors and protein markers affecting susceptibility to non-small cell lung cancer in...

Call: OPUS 8 , Panel: NZ5

Principal investigator: prof. Piotr Kuśnierczyk

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Studies on receptor layers formed by DNA and RNA aptamers in respect of their potential application in biosensors for de...

Call: PRELUDIUM 8 , Panel: ST4

Principal investigator: dr Marta Jarczewska

POLITECHNIKA WARSZAWSKA

Impact evaluation of pigeon circovirus recombinant capsid protein on the development of selected immune phenomena in pig...

Call: SONATA 8 , Panel: NZ6

Principal investigator: dr hab. Tomasz Stenzel

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Medycyny Weterynaryjnej

Transcriptomic analysis of tumor cells treated with the synergistic combination of substences activating p53 protein- se...

Call: SONATA 8 , Panel: NZ5

Principal investigator: dr Agnieszka Gdowicz-Kłosok

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Structure-based dynamical models of large and complex biomolecular systems

Call: OPUS 8 , Panel: ST3

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in ...

Call: SONATA 8 , Panel: NZ4

Principal investigator: dr Anna Mietelska-Porowska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Oxidative stress during thermogenesis in laboratory mice with genetic variation in maximum and basal metabolic rate: the...

Call: OPUS 8 , Panel: NZ8

Principal investigator: dr hab. Paweł Brzęk

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

Pathophysiological consequences of histone N-homocysteinylation in hyperhomocysteinemia caused by CBS deficiency

Call: PRELUDIUM 8 , Panel: NZ5

Principal investigator: Izabela Lewandowska

Instytut Chemii Bioorganicznej PAN

Synthesis of fluorogenic substrates, inhibitors and activity-based probes of human neutrophil proteinase NSP4 and its ev...

Call: OPUS 8 , Panel: ST5

Principal investigator: prof. Adam Lesner

Uniwersytet Gdański, Wydział Chemii

Identification and comprehensive classification of nucleases including human nucleases

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr hab. Krzysztof Ginalski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain.

Call: SONATA 8 , Panel: NZ1

Principal investigator: dr Maria Górna

Uniwersytet Warszawski, Wydział Chemii

Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Protein control by ubiquitin/proteasome system in plant response to sulfate deprivation

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr Anna Wawrzyńska

Instytut Biochemii i Biofizyki PAN

LEW1 as a protein partner for cis-prenyltransferases in polyisoprenoid biosynthesis in Arabidopsis

Call: PRELUDIUM 8 , Panel: NZ1

Principal investigator: Przemysław Surowiecki

Instytut Biochemii i Biofizyki PAN

Upstream regulators and cellular targets of the selective autophagy cargo receptor AtNBR1 in different phases of sulfur ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Agnieszka Sirko

Instytut Biochemii i Biofizyki PAN

Characteristics of nucleotide sugar transporters SLC35A4 and SLC35A5

Call: PRELUDIUM 8 , Panel: NZ1

Principal investigator: Paulina Sosicka

Uniwersytet Wrocławski, Wydział Biotechnologii

Mechanistic insight in Transmembrane Protein (TMEM) deregulation and its contribution to ccRCC etiology

Call: OPUS 8 , Panel: NZ2

Principal investigator: dr hab. Joanna Wesoły

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The influence of bone marrow microenvironment on the regulation of BRCA1 mRNA translation in leukemia cells; role in the...

Call: SONATA 8 , Panel: NZ3

Principal investigator: dr Paulina Podszywałow-Bartnicka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The role of bacterial sRNAs interaction with distal face of chaperone protein Hfq

Call: PRELUDIUM 8 , Panel: NZ1

Principal investigator: Ewelina Małecka-Grajek

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Make a jump into understanding of selective ribosome-dependent translation in plant mitochondria.

Call: OPUS 8 , Panel: NZ2

Principal investigator: prof. Hanna Jańska

Uniwersytet Wrocławski, Wydział Biotechnologii

Protein targeting to degradation: a new role of ABI1 protein phosphatase 2C in ethylene biosynthesis

Call: OPUS 8 , Panel: NZ3

Principal investigator: dr Agnieszka Ludwików

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Regulation of mechanisms of iron and heme acquisition and virulence in Porphyromonas gingivalis with involvement of PgFu...

Call: OPUS 8 , Panel: NZ6

Principal investigator: prof. Teresa Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Global analysis of protein expression regulated by pregnancy-associated microRNAs in the porcine endometrial cells in vi...

Call: PRELUDIUM 1 , Panel: NZ2

Principal investigator: dr Kamil Krawczyński

Instytut Rozrodu Zwierząt i Badań Żywności, Polska Akademia Nauk

The functional meaning of the protein kinase C beta (PKC beta) translocation due to cerebral ischemia. Solving the puzzl...

Call: SONATA 8 , Panel: NZ3

Principal investigator: dr Małgorzata Beręsewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identification of circular RNAs and protein factors involved in their biogenesis in a model plant, Arabidopsis thaliana

Call: SONATA 8 , Panel: NZ2

Principal investigator: dr Anna Philips

Instytut Chemii Bioorganicznej PAN

Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc ...

Call: OPUS 8 , Panel: ST4

Principal investigator: prof. Maciej Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Biodegradable poly(N-vinylpyrrolidone) hydrogels containing trehalose as bioprotective protein carriers

Call: PRELUDIUM 8 , Panel: ST8

Principal investigator: Małgorzata Burek

Politechnika Śląska, Wydział Chemiczny

The ability of Lactobacillus helveticus strains to a production of biologically active peptides - an antioxidative prope...

Call: PRELUDIUM 8 , Panel: NZ9

Principal investigator: Katarzyna Skrzypczak

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Structural biology of mixed lineage leukemia (MLL) proteins

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: prof. Matthias Bochtler

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mec...

Call: SONATA BIS 4 , Panel: NZ1

Principal investigator: prof. Tomasz Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

Approach to structures of difficult protein targets using new mass spectrometry-based methods

Call: MAESTRO 6 , Panel: NZ1

Principal investigator: prof. Michał Dadlez

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Identification of proteins locally synthesized at the synapse in response to neuronal stimulation in physiology and frag...

Call: SONATA BIS 4 , Panel: NZ3

Principal investigator: dr hab. Magdalena Dziembowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Role of primary cilia in the activation of Gli transcription factors in Hedgehog signaling

Call: SONATA BIS 4 , Panel: NZ3

Principal investigator: dr hab. Paweł Niewiadomski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono...

Call: SONATA BIS 4 , Panel: ST5

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny