Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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LABORATORY EVOLUTION OF SUPERCHARGED PROTEINS USING A SUPERCHARGED PROTEIN NANOCAGE

2018/31/D/NZ1/01102

Keywords:

Supercharging Directed Evolution Protein cage Fluorescent Protein Protein engineering

Descriptors:

  • NZ1_9:
  • ST5_16:
  • NZ1_6:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Yusuke Azuma 

Number of co-investigators in the project: 4

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 1 528 160 PLN

Project start date (Y-m-d): 2019-10-03

Project end date (Y-m-d): 2023-10-02

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  • Book publications / chapters in book publications (1)
  1. Complementary charge-driven encapsulation of functional protein by engineered protein cages in cellulo
    Authors:
    Daniel Zakaszewski, Lukasz Koziej, Jędrzej Pankowski, V. Vishal Malolan, Nina Gämperli, Jonathan G. Heddle, Donald Hilvert, and Yusuke Azuma
    Academic press:
    Journal of Materials Chemistry B (rok: 2023, tom: 11, strony: 6540-6546), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D3TB00754E - link to the publication
  2. Dynamic Assembly of Pentamer-Based Protein Nanotubes
    Authors:
    Lukasz Koziej Farzad Fatehi, Marta Aleksejczuk, Matthew J. Byrne, Jonathan G. Heddle, Reidun Twarock, and Yusuke Azuma
    Academic press:
    ACS Nano (rok: 2025, tom: 19, strony: 8786-8798), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnano.4c16192 - link to the publication
  3. Connectability of protein cages
    Authors:
    Karolina Majsterkiewicz, Yusuke Azuma, and Jonathan G. Heddle
    Academic press:
    Nanoscale Advances (rok: 2020, tom: 2, strony: 2255-2264), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0NA00227E - link to the publication
  1. Complementary Charge-driven Encapsulation of Functional Protein by Engineered Protein Cages in Cellulo
    Authors:
    Daniel Zakaszewski, Lukasz Koziej, Jędrzej Pankowski, V. Vishal Malolan, Nina Gämperli, Jonathan G Heddle, Donald Hilvert, and Yusuke Azuma
    Conference:
    Journal of Materials Chemistry B (rok: 2023, ), Wydawca: Royal Society of Chemistry
    Data:
    konferencja 46213
    Status:
    Published
  1. Lumazine Synthase Protein Nanocompartments
    Authors:
    Lukasz Koziej, Agnieszka Gawin, and Yusuke Azuma
    Book:
    Microbiology Monographs, Microbial Production of High-Value Products (rok: 2022, tom: 37, strony: pp335-355), Wydawca: Springer-Nature Switzerland AG, Cham, Switzerland
    Status:
    Published

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