LABORATORY EVOLUTION OF SUPERCHARGED PROTEINS USING A SUPERCHARGED PROTEIN NANOCAGE

2018/31/D/NZ1/01102

Keywords

Descriptors

  • NZ1_9: Biotechnologia
  • ST5_16: Chemia biologiczna
  • NZ1_6: Biologia syntetyczna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Yusuke Azuma

Number of co-investigators in the project: 4

Call

SONATA 14 – announced on 2018-09-14

Amount awarded
1 528 160 PLN
Project start date
2019-10-03
Project end date
2023-10-02
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Complementary charge-driven encapsulation of functional protein by engineered protein cages in cellulo

    Authors:
    Daniel Zakaszewski, Lukasz Koziej, Jędrzej Pankowski, V. Vishal Malolan, Nina Gämperli, Jonathan G. Heddle, Donald Hilvert, and Yusuke Azuma
    Academic press:
    Journal of Materials Chemistry B (year: 2023, volume: 11, pages: 6540-6546), Publisher: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D3TB00754E – link to the publication
  2. Connectability of protein cages

    Authors:
    Karolina Majsterkiewicz, Yusuke Azuma, and Jonathan G. Heddle
    Academic press:
    Nanoscale Advances (year: 2020, volume: 2, pages: 2255-2264), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0NA00227E – link to the publication
  3. Dynamic Assembly of Pentamer-Based Protein Nanotubes

    Authors:
    Lukasz Koziej Farzad Fatehi, Marta Aleksejczuk, Matthew J. Byrne, Jonathan G. Heddle, Reidun Twarock, and Yusuke Azuma
    Academic press:
    ACS Nano (year: 2025, volume: 19, pages: 8786-8798), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnano.4c16192 – link to the publication

Articles in post-conference publications (1)

  1. Complementary Charge-driven Encapsulation of Functional Protein by Engineered Protein Cages in Cellulo

    Authors:
    Daniel Zakaszewski, Lukasz Koziej, Jędrzej Pankowski, V. Vishal Malolan, Nina Gämperli, Jonathan G Heddle, Donald Hilvert, and Yusuke Azuma
    Conference:
    Journal of Materials Chemistry B (year: 2023, pages: 6540-6546), Publisher: Royal Society of Chemistry
    Date:
    conference 46213
    Status:
    Published

Book publications / chapters in book publications (1)

  1. Lumazine Synthase Protein Nanocompartments

    Authors:
    Lukasz Koziej, Agnieszka Gawin, and Yusuke Azuma
    Book:
    Microbiology Monographs, Microbial Production of High-Value Products (year: 2022, volume: 37, pages: pp335-355), Publisher: Springer-Nature Switzerland AG, Cham, Switzerland
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski