Downregulation of Iron Regulatory Protein 1 expression in oxidative stress: molecular mechanisms, impact on intracellular iron metabolism, importance in the pathogenesis of Amyotropic Lateral Sclerosis
2011/01/B/NZ3/00632
Keywords
Descriptors
- NZ3_2: Fizjologia komórki
- NZ3_1: Biologia komórki
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Instytut Genetyki i Hodowli Zwierząt PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
OPUS 1 – announced on 2011-03-15
- Amount awarded
- 352 000 PLN
- Project start date
- 2011-12-19
- Project end date
- 2015-06-18
- Project duration
- 42 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (3)
-
Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1G93A Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis
- Authors:
- Anna Gajowiak, Agnieszka Styś, Rafał R. Starzyński, Aleksandra Bednarz, Małgorzata Lenartowicz, Robert Staroń and Paweł Lipiński
- Academic press:
- Frontiers in Molecular Neuroscience (year: 2016, volume: 8 (article 82), pages: 46037), Publisher: Frontiers Media
- Status:
- Published
- DOI:
- 10.3389/fnmol.2015.00082 – link to the publication
-
Zaburzenie hoemostazy żelaza w stwardnieniu zanikowym bocznym
- Authors:
- Anna Gajowiak, Agnieszka Styś, Rafał R. Starzyński, Robert Staroń, Paweł Lipiński
- Academic press:
- Postępy Higieny i Medycyny Doświadczalnej (year: 2016, volume: 70, pages: 709-721), Publisher: Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN
- Status:
- Published
- DOI:
- 10.5604/17322693.1208036 – link to the publication
-
Metabolizm hemu jako integralny element homeostazy żelaza
- Authors:
- Paweł Lipiński, Rafał R. Starzyński, Agnieszka Styś, Anna Gajowiak, Robert Staroń
- Academic press:
- Postępy Higieny i Medycyny Doświadczalnej (year: 2014, volume: 68, pages: 557-570), Publisher: Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN
- Status:
- Published
Articles in post-conference publications (1)
-
Overexpression of both non-muteted human SOD1 and mutated SOD1G93A genes induces changes of iron metabolism genes in mice
- Authors:
- Anna Gajowiak, Rafał R. Starzyński, Paweł Lipiński, Robert Staroń, Agnieszka Styś
- Conference:
- 2nd Meeting of the Polish Iron Club (Ferrum Rex) (year: 2015, pages: 20), Publisher: Polskie Towarzystwo Anatomicze, Polskie Towarzystwo Biologii Komórki
- Date:
- conference 12-13 maja
- Status:
- Published