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Do miRNA determine cell fate during unfolded protein response (UPR) ?

2015/17/B/NZ3/01485

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_2: Biochemia
  • NZ3_1: Biologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Gdański Uniwersytet Medyczny

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Rafał Artur Bartoszewski

Number of co-investigators in the project: 5

Call

OPUS 9 – announced on 2015-03-16

Amount awarded
1 036 440 PLN
Project start date
2016-02-16
Project end date
2020-02-15
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw do analiz PCR w czasie rzeczywistym (real time PCR). Cost: 26 911 PLN

Information in the final report

Publication in academic press/journals (6)

  1. Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia

    Authors:
    Sylwia Bartoszewska, James F. Collawn
    Academic press:
    Cellular and Molecular Biology Letters (year: 2020, volume: 25, pages: BRAK), Publisher: BMC SPRINGER
    Status:
    Published
    DOI:
    10.1186/s11658-020-00212-1 – link to the publication

  2. Genome-wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress.

    Authors:
    Bartoszewski R, Gebert M, Janaszak-Jasiecka A, Cabaj A, Króliczewski J, Bartoszewska S, Sobolewska A, Crossman DK, Ochocka R, Kamysz W, Kalinowski L, Dąbrowski M, Collawn JF
    Academic press:
    FEBS Journal (year: 2020, volume: brak, pages: brak), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/febs.15195 – link to the publication

  3. SNPs in microRNA target sites and their potential role in human disease

    Authors:
    Moszynska, Adrianna ; Gebert, Magdalena ; Collawn, James F; Bartoszewski, Rafal
    Academic press:
    OPEN BIOLOGY (year: 2017, volume: 7 (4), pages: nd), Publisher: ROYAL SOC, 6-9 CARLTON HOUSE TERRACE, LONDON SW1Y 5AG, ENGLAND
    Status:
    Published
    DOI:
    10.1098/rsob.170019 – link to the publication

  4. microRNA single polynucleotide polymorphism influences on microRNA biogenesis and mRNA target specificity

    Authors:
    Kroliczewski, Jaroslaw; Sobolewska, A; Lejnowski, Dawid; Collawn, James F. ; Bartoszewski, R
    Academic press:
    Gene (year: 2018, volume: 640, pages: 665-72), Publisher: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.gene.2017.10.021 – link to the publication

  5. PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells

    Authors:
    Magdalena Gebert, Sylwia Bartoszewska, Anna Janaszak-Jasiecka, Adrianna Moszyńska, Aleksandra Cabaj, Jarosław Króliczewski, Piotr Madanecki, Renata J Ochocka, David K Crossman, James F Collawn, Rafal Bartoszewski
    Academic press:
    Scientific Reports (year: 2018, volume: 8, pages: 16431 (2018)), Publisher: Nature Springer
    Status:
    Published
    DOI:
    10.1038/s41598-018-34861-2 – link to the publication

  6. miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response

    Authors:
    Sylwia Bartoszewska, Aleksandra Cabaj, Michał Dąbrowski, James F. Collawn and Rafal Bartoszewski
    Academic press:
    FASEB J (year: 2019, volume: 33, pages: 11541-11554), Publisher: FASEB J
    Status:
    Published
    DOI:
    10.1096/fj.201900600RR – link to the publication

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