Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Do miRNA determine cell fate during unfolded protein response (UPR) ?

2015/17/B/NZ3/01485

Keywords:

microRNA UPR unfolded protein response

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Rafał Bartoszewski 

Number of co-investigators in the project: 5

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 1 036 440 PLN

Project start date (Y-m-d): 2016-02-16

Project end date (Y-m-d): 2020-02-15

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw do analiz PCR w czasie rzeczywistym (real time PCR) (26 911 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response
    Authors:
    Sylwia Bartoszewska, Aleksandra Cabaj, Michał Dąbrowski, James F. Collawn and Rafal Bartoszewski
    Academic press:
    FASEB J (rok: 2019, tom: 33, strony: 11541-11554), Wydawca: FASEB J
    Status:
    Published
    DOI:
    10.1096/fj.201900600RR - link to the publication
  2. PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells
    Authors:
    Magdalena Gebert, Sylwia Bartoszewska, Anna Janaszak-Jasiecka, Adrianna Moszyńska, Aleksandra Cabaj, Jarosław Króliczewski, Piotr Madanecki, Renata J Ochocka, David K Crossman, James F Collawn, Rafal Bartoszewski
    Academic press:
    Scientific Reports (rok: 2018, tom: 8, strony: 16431 (2018)), Wydawca: Nature Springer
    Status:
    Published
    DOI:
    10.1038/s41598-018-34861-2 - link to the publication
  3. Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
    Authors:
    Sylwia Bartoszewska, James F. Collawn
    Academic press:
    Cellular and Molecular Biology Letters (rok: 2020, tom: 25, strony: BRAK), Wydawca: BMC SPRINGER
    Status:
    Published
    DOI:
    10.1186/s11658-020-00212-1 - link to the publication
  4. Genome-wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress.
    Authors:
    Bartoszewski R, Gebert M, Janaszak-Jasiecka A, Cabaj A, Króliczewski J, Bartoszewska S, Sobolewska A, Crossman DK, Ochocka R, Kamysz W, Kalinowski L, Dąbrowski M, Collawn JF
    Academic press:
    FEBS Journal (rok: 2020, tom: brak, strony: brak), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/febs.15195 - link to the publication
  5. SNPs in microRNA target sites and their potential role in human disease
    Authors:
    Moszynska, Adrianna ; Gebert, Magdalena ; Collawn, James F; Bartoszewski, Rafal
    Academic press:
    OPEN BIOLOGY (rok: 2017, tom: 7 (4), strony: nd), Wydawca: ROYAL SOC, 6-9 CARLTON HOUSE TERRACE, LONDON SW1Y 5AG, ENGLAND
    Status:
    Published
    DOI:
    10.1098/rsob.170019 - link to the publication
  6. microRNA single polynucleotide polymorphism influences on microRNA biogenesis and mRNA target specificity
    Authors:
    Kroliczewski, Jaroslaw; Sobolewska, A; Lejnowski, Dawid; Collawn, James F. ; Bartoszewski, R
    Academic press:
    Gene (rok: 2018, tom: 640, strony: 665-72), Wydawca: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.021 - link to the publication

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