Projects funded by the NCN

Integrity of E3 ubiquitin ligase complex as a biomarker of response to treatment with immunomodulatory drugs in patients...

Call: OPUS 7 , Panel: NZ5

Principal investigator: Ewa Lech-Marańda

Instytut Hematologii i Transfuzjologii

Characteristics of neuropilin-1 (NRP1) as a target of antiangiogenic activity of immunomodulatory drugs in multiple myel...

Call: OPUS 7 , Panel: NZ6

Principal investigator: prof. Krzysztof Giannopoulos

Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

Analysis of the effect of the DIS3 mutations on the viability, development and tumor formation in mice

Call: HARMONIA 5 , Panel: NZ4

Principal investigator: dr hab. Andrzej Stanisław Dziembowski

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

The influence of hypoxia on functional features of multiple myeloma cells

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: dr Kinga Anna Kocemba

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Lipid antigens as a target for autoimmune attack in multiple sclerosis.

Call: HARMONIA 4 , Panel: NZ3

Principal investigator: dr Maria Anna Podbielska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Prolonged-release of selected antiangiogenic proteins from innovative nanocarrier for use in adjuvant/additive multiple ...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Bogusław Bronisław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie

Characteristics of anti-lipid IgG antibodies in patients with relapsing-remitting multiple sclerosis: physico-chemical p...

Call: PRELUDIUM 23 , Panel: NZ3

Principal investigator: Anna Izabela Jakubiak-Augustyn

Uniwersytet Wrocławski

EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

Call: SONATA 18 , Panel: NZ3

Principal investigator: dr hab. Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

The role of the gut microbiota in the pathogenesis of plasma cell dyscrasias

Call: PRELUDIUM 21 , Panel: NZ6

Principal investigator: Marcin Mateusz Jasiński

Warszawski Uniwersytet Medyczny

Uracil in DNA and aberrant DNA methylation/hydroxymethylation as a new biomarkers of multiple myeloma development? A sea...

Call: OPUS 20 , Panel: NZ5

Principal investigator: prof. Ryszard Oliński

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

Gankyrin protein as a new potential therapeutic target in multiple myeloma

Call: OPUS 18 , Panel: NZ5

Principal investigator: dr hab. Irena Misiewicz-Krzemińska

Instytut Hematologii i Transfuzjologii

Role of the human RNA exosome catalytic subunit DIS3 in multiple myeloma pathogenesis and cell physiology.

Call: MAESTRO 1 , Panel: NZ1

Principal investigator: prof. Andrzej Stanisław Dziembowski

Uniwersytet Warszawski, Wydział Biologii

How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

Call: SONATINA 3 , Panel: NZ2

Principal investigator: dr Tomasz M. Kuliński

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

The role of PIM kinases in the vascular niche of multiple myeloma

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: Filip Aleksander Garbicz

Instytut Hematologii i Transfuzjologii

Multi-omics profiling of circulating myeloid-derived suppressor cells (cMDSCs) in epithelial ovarian cancer

Call: PRELUDIUM 16 , Panel: NZ2

Principal investigator: dr Karolina Okła

Uniwersytet Medyczny w Lublinie

Determining the role of basigin in multiple myeloma and acute myeloid leukaemia development

Call: PRELUDIUM 15 , Panel: NZ5

Principal investigator: Piotr Stanisław Łacina

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

Call: PRELUDIUM 15 , Panel: NZ5

Principal investigator: Tadeusz Franciszek Kubicki

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

Cognitive functioning of patients with multiple myeloma and biological factors as well as psychosocial variables shaping...

Call: PRELUDIUM 14 , Panel: HS6

Principal investigator: Magdalena Bury-Kamińska

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Pedagogiki i Psychologii

The role of Fam46C in B cell phisiology

Call: OPUS 14 , Panel: NZ2

Principal investigator: dr Seweryn Mroczek

Uniwersytet Warszawski, Wydział Biologii

Determination of arginase-1 as a potential drug target in the treatment of multiple myeloma and in reducing proteasome i...

Call: OPUS 13 , Panel: NZ6

Principal investigator: prof. Jakub Adam Gołąb

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Proteomic analysis of myeloma plasma cells to determine proteins and pathways involved in acquired resistance to proteas...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Dominik Dytfeld

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors...

Call: OPUS 12 , Panel: NZ5

Principal investigator: prof. Tadeusz Jerzy Robak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The role of neurotrophins and angiogenic cytokines in the pathophysiology of treatment-induced peripheral neuropathy in ...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Bogusław Bronisław Machaliński

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Medycyny i Stomatologii

Oncogenic mechanisms of DIS3 mutations

Call: MAESTRO 8 , Panel: NZ4

Principal investigator: prof. Andrzej Stanisław Dziembowski

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Evaluation of anticancer potential of glutamine metabolism modulation in multiple myeloma sensitive and resistant to che...

Call: PRELUDIUM 11 , Panel: NZ5

Principal investigator: Monika Katarzyna Prełowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego