Projects funded by the NCN

The JAK/STAT pathway as a molecular contributor to the development of endometriosis: therapeutic potential of JAK inhibi...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Aleksander Radosław Rycerz

Uniwersytet Medyczny w Łodzi

Dual cell cycle blockade and immune checkpoint inhibition as a potential strategy of sequential anticancer therapy

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Alicja Stanisława Słota

Uniwersytet Jagielloński

Dynamic RNA structures including pseudoknots and G-quadruplexes of influenza type A virus RNAs as targets for designing ...

Call: SHENG 4 , Panel: NZ1

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Radosław Dariusz Kitel

Uniwersytet Jagielloński

Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

Call: OPUS 28 , Panel: NZ6

Principal investigator: dr Renata Grzywa

Politechnika Wrocławska

Where Inhibition is not Enough- Development of Innovative Compounds for Targeted Degradation of Extracellular and Membra...

Call: OPUS 28 (LAP) , Panel: NZ5

Principal investigator: dr Marcin Skoreński

Politechnika Wrocławska

INFLOXAR - Investigation of causes of atrioventricular conduction disorders with comparison of muscle and physiological ...

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Jakub Wojciech Szyller

Politechnika Wrocławska

Novel hybrid coatings with advanced antimicrobial properties for surface modification in atmospheric water harvesting sy...

Call: OPUS 27 , Panel: ST11

Principal investigator: prof. Anna Elżbieta Kowalewska

Centrum Badań Molekularnych i Makromolekularnych PAN

The human ear dynamics stimulated by piezoelectric membrane - novel hybrid model

Call: OPUS 27 , Panel: ST8

Principal investigator: prof. Rafał Sławomir Rusinek

Politechnika Lubelska

Characterization of sensitivity of cones and rods to two-photon stimulation

Call: OPUS 27 , Panel: ST7

Principal investigator: dr Katarzyna Paulina Komar

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Autophagy stimulation by genistein to cure Alzheimer disease: mechanisms and effects investigated using genetic (cellula...

Call: OPUS 27 , Panel: NZ2

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański

Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

Call: PRELUDIUM 23 , Panel: ST5

Principal investigator: Aleksandra Dorota Helbik-Maciejewska

Uniwersytet Gdański

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Interaction between temporal predictability and action control in ADHD and Parkinson's Disease: behavioural, neurophysio...

Call: SONATINA 8 , Panel: HS6

Principal investigator: dr Inga Justyna Korolczuk

Uniwersytet Medyczny w Lublinie

Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Artur Świerczek

Uniwersytet Jagielloński, Collegium Medicum

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

Call: OPUS 26 (LAP) , Panel: NZ7

Principal investigator: dr Anna Czarna

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr Bartosz Sebastian Pomierny

Uniwersytet Jagielloński, Collegium Medicum

Physiological significance and clinical implications of global and local inhibition of NRF2 transcriptional activity in ...

Call: SONATA BIS 13 , Panel: NZ4

Principal investigator: dr hab. Aleksandra Barbara Piechota-Polańczyk

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

The effect of Tcf7l2 knockout on excitation/inhibition balance in neuronal circuits of the thalamus

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Katarzyna Aleksandra Hryniewiecka

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Combining microfluidic-assisted biofabrication with high throughput proteomics to unravel skeletal muscle plasticity und...

Call: SONATINA 7 , Panel: ST5

Principal investigator: dr Nehar Celikkin

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Electrical stimulation of Anterior Thalamic Nuclei for memory modulation

Call: POLONEZ BIS 3 , Panel: NZ4

Principal investigator: dr Maciej Michal Jankowski

Politechnika Gdańska

Targeted inhibition of hypusination pathway

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr Przemysław Marek Grudnik

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Multidimensional mechanistic investigations of trans spinal direct current stimulation in motor neuron disease.

Call: JPND Call 2022 , Panel: NZ4

Principal investigator: dr Marcin Bączyk

Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu

Selective determination of isoenzymatic lactate dehydrogenase activity in flow analysis format

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Justyna Weronika Głowacka-Gudanek

Uniwersytet Warszawski, Wydział Chemii

Rhythms of attention: The functional and causal role of neural oscillations in selective attention.

Call: OPUS 23 , Panel: HS6

Principal investigator: dr hab. Dariusz Asanowicz

Uniwersytet Jagielloński, Wydział Filozoficzny

Mycogenic metal nanoparticles for plant growth stimulation and increased plant production.

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: Joanna Trzcińska-Wencel

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

Mechanisms and therapeutic potential of SGLT2/SGLT1 and NHE-1 inhibition in a rat model of heart failure with preserved ...

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Urszula Mackiewicz

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Kinga Maria Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Biocompatible materials with theranostics' properties for precision medical application

Call: OPUS 22 , Panel: ST5

Principal investigator: prof. Rafał Jakub Wiglusz

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Stimulation and regulation of growth of biofilm and microalgae and cyanobacteria in photosynthetic microbial fuel cell

Call: OPUS 21 , Panel: NZ9

Principal investigator: prof. Marcin Zieliński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Geoinżynierii

Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Barbara Malinowska

Uniwersytet Medyczny w Białymstoku

Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor...

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: dr Konrad Mateusz Pakuła

Instytut Chemii Bioorganicznej PAN

Studies on potential significance of yolkin, an egg yolk-derived protein, in maturation, enhancement and regulation of t...

Call: OPUS 21 , Panel: NZ6

Principal investigator: prof. Michał Zimecki

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

Call: OPUS 21 , Panel: NZ1

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Advanced algorithms for identification of electrophysiological features underlying encoding and recall of human memory i...

Call: WEAVE-UNISONO , Panel: NZ4

Principal investigator: dr Michał Tomasz Kucewicz

Politechnika Gdańska

The effects of transcutaneous vagus nerve stimulation combined with slow breathing on pain as well as affective and auto...

Call: SONATINA 5 , Panel: HS6

Principal investigator: dr Mikołaj Tytus Szulczewski

Instytut Psychologii PAN

The role of somatostatin- and parvalbumin interneurons in the modulation of neuronal function and synaptic plasticity vi...

Call: OPUS 20 , Panel: NZ4

Principal investigator: dr hab. Joanna Małgorzata Urban-Ciećko

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Tomasz Marcin Wróbel

Uniwersytet Medyczny w Lublinie

Recording and modulation of high frequency neurophysiological activities underlying encoding and recall of human memory.

Call: OPUS 20 (LAP) , Panel: NZ4

Principal investigator: dr Michał Tomasz Kucewicz

Politechnika Gdańska

Hybrid carbon composites for stimulation of cells of the central nervous system

Call: OPUS 20 , Panel: ST5

Principal investigator: dr hab. Aneta Frączek-Szczypta

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Dorota Gudanis-Sobocińska

Instytut Chemii Bioorganicznej PAN

The influence of natural plant extracts obtained by supercritical extraction on the replication inhibition of the most i...

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Grzegorz Jan Woźniakowski

Uniwersytet Mikołaja Kopernika

Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

Call: OPUS 20 , Panel: NZ1

Principal investigator: prof. Elżbieta Beata Kierzek

Instytut Chemii Bioorganicznej PAN

The multifaceted nature of indecisiveness and its influence on cognitive control: A neurophysiological approach

Call: SONATA BIS 10 , Panel: HS6

Principal investigator: dr hab. Magdalena Senderecka

Uniwersytet Jagielloński, Wydział Filozoficzny

Molecular mechanisms of genistein-mediated autophagy stimulation, and its cellular and physiological effects in Huntingt...

Call: OPUS 19 , Panel: NZ2

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański, Wydział Biologii