Projects funded by the NCN
The role of somatostatin- and parvalbumin interneurons in the modulation of neuronal function and synaptic plasticity via the activation of GABAb receptors.
2020/39/B/NZ4/01462
Keywords:
Electrophysiology whole-cell patch-clamp neocortex GABAergic inhibition brain plasticity synaptic transmission
Descriptors:
- NZ4_007:
- NZ3_007:
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
dr hab. Joanna Małgorzata Urban-Ciećko
Number of co-investigators in the project: 3
Call: OPUS 20 - announced on 2020-09-15
Amount awarded: 2 945 196 PLN
Project start date (Y-m-d): 2021-08-02
Project end date (Y-m-d): 2025-08-01
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- Somatostatin-expressing interneurons modulate neocortical network through GABAb receptors in a synapse-specific manner.Authors:Kanigowski D, Bogaj K, Barth AL, Urban-Ciecko J.Academic press:Scientific Reports (rok: 2023, tom: 13, strony: 8780 (1-16)), Wydawca: Springer NatureStatus:PublishedDOI:10.1038/s41598-023-35890-2 - link to the publication
- GABAAR-mediated tonic inhibition differentially modulates intrinsic excitability of VIP- and SST- expressing interneurons in layers 2/3 of the somatosensory cortex.Authors:Bogaj K, Kaplon R, Urban-Ciecko J.Academic press:Frontiers in Cellular Neuroscience (rok: 2023, tom: 17, strony: 1270219 (1-13)), Wydawca: Frontiers MediaStatus:PublishedDOI:10.3389/fncel.2023.1270219 - link to the publication
- GABAAR-mediated tonic inhibition differentially modulates intrinsic excitability of VIP- and SST- expressing interneurons in layers 2/3 of the somatosensory cortex.Authors:Bogaj K, Kaplon R, Urban-Ciecko J.Academic press:Front Cell Neurosci. (rok: 2023, tom: 17, strony: 1270219 (1-13)), Wydawca: Frontiers MediaStatus:PublishedDOI:10.3389/fncel.2023.1270219 - link to the publication