The role of somatostatin- and parvalbumin interneurons in the modulation of neuronal function and synaptic plasticity via the activation of GABAb receptors.
2020/39/B/NZ4/01462
Keywords
Descriptors
- NZ4_007: Neurofizjologia
- NZ3_007: Przekaźnictwo sygnału
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
dr hab. Joanna Małgorzata Urban-Ciećko
Number of co-investigators in the project: 3
Call
OPUS 20 – announced on 2020-09-15
- Amount awarded
- 2 945 196 PLN
- Project start date
- 2021-08-02
- Project end date
- 2027-08-01
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (3)
-
Inhibition of BK channels by GABAb receptors enhances intrinsic excitability of layer 2/3 vasoactive intestinal polypeptide-expressing interneurons in mouse neocortex.
- Authors:
- Bogaj K, Urban-Ciecko J
- Academic press:
- The Journal of Physiology (year: 2025, volume: 603(5), pages: 1171-1196), Publisher: John Wiley & Sons Ltd
- Status:
- Published
- DOI:
- 10.1113/JP286439 – link to the publication
-
Somatostatin-expressing interneurons modulate neocortical network through GABAb receptors in a synapse-specific manner.
- Authors:
- Kanigowski D, Bogaj K, Barth AL, Urban-Ciecko J.
- Academic press:
- Scientific Reports (year: 2023, volume: 13, pages: 8780 (1-16)), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-023-35890-2 – link to the publication
-
GABAAR-mediated tonic inhibition differentially modulates intrinsic excitability of VIP- and SST- expressing interneurons in layers 2/3 of the somatosensory cortex.
- Authors:
- Bogaj K, Kaplon R, Urban-Ciecko J.
- Academic press:
- Frontiers in Cellular Neuroscience (year: 2023, volume: 17, pages: 1270219 (1-13)), Publisher: Frontiers Media
- Status:
- Published
- DOI:
- 10.3389/fncel.2023.1270219 – link to the publication