Projects funded by the NCN


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63 projects found matching your search criteria :

  1. The involvement of IL-10 in the activation of the suppression mechanism utilized by myeloid-derived suppressor cells - d...

    Call: PRELUDIUM 8 , Panel: NZ4

    Principal investigator: Natalia Magdalena Anger

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  2. Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Tomasz Artur Stokłosa

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  3. Integrity of E3 ubiquitin ligase complex as a biomarker of response to treatment with immunomodulatory drugs in patients...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: Ewa Lech-Marańda

    Instytut Hematologii i Transfuzjologii

  4. Characteristics of neuropilin-1 (NRP1) as a target of antiangiogenic activity of immunomodulatory drugs in multiple myel...

    Call: OPUS 7 , Panel: NZ6

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  5. Mechanism of SYK-mediated suppression of differentiation and apoptosis in acute myeloid leukemia (AML)

    Call: PRELUDIUM 6 , Panel: NZ5

    Principal investigator: dr Anna Polak

    Instytut Hematologii i Transfuzjologii

  6. The regulation of vitamin D receptor expression by retinoids

    Call: PRELUDIUM 6 , Panel: NZ3

    Principal investigator: Aleksandra Ludwika Marchwicka

    Uniwersytet Wrocławski, Wydział Biotechnologii

  7. Transcriptional-epigenetic role of poly(ADP-ribose) polymerase-1 in expression of pro-inflammatory mediators controlled ...

    Call: SONATA 6 , Panel: NZ2

    Principal investigator: dr Agnieszka Robaszkiewicz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  8. Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Flis

    Narodowy Instytut Leków

  9. The role of nucelophosmin-1 exon 12 abnormalities in acute myeloid leukemias and myelodyplastic syndrome

    Call: HARMONIA 5 , Panel: NZ5

    Principal investigator: Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  10. Analysis of the effect of the DIS3 mutations on the viability, development and tumor formation in mice

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Andrzej Stanisław Dziembowski

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  11. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme...

    Call: SONATA BIS 3 , Panel: NZ5

    Principal investigator: prof. Dominika Anna Nowis

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  12. The influence of hypoxia on functional features of multiple myeloma cells

    Call: PRELUDIUM 5 , Panel: NZ1

    Principal investigator: dr Kinga Anna Kocemba

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  13. Analysis of oligodendrocyte differentiation and maturation of St8sia2 knockout mice - a model of polysialylation deficie...

    Call: PRELUDIUM 5 , Panel: NZ3

    Principal investigator: dr Łukasz Szewczyk

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  14. Lipid antigens as a target for autoimmune attack in multiple sclerosis.

    Call: HARMONIA 4 , Panel: NZ3

    Principal investigator: dr Maria Anna Podbielska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  15. Investigation of the role of ficolins in anti-microbial defense in patients suffering from acute myeloid leukaemia, unde...

    Call: PRELUDIUM 4 , Panel: NZ6

    Principal investigator: Anna Katarzyna Sokołowska

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  16. Role of Myeloid Derived Suppressor Cells in Heligmosomoides polygyrus infection in mice

    Call: PRELUDIUM 3 , Panel: NZ6

    Principal investigator: Klaudia Klarysa Brodaczewska

    Uniwersytet Warszawski, Wydział Biologii

  17. Role of myeloid dendritic cells in immune response polarization in resistant (C57BL/6) and susceptible (BALB/c) mice dur...

    Call: SONATA 3 , Panel: NZ6

    Principal investigator: dr Lidia Agnieszka Szulc-Dąbrowska

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  18. Prolonged-release of selected antiangiogenic proteins from innovative nanocarrier for use in adjuvant/additive multiple ...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Bogusław Bronisław Machaliński

    Pomorski Uniwersytet Medyczny w Szczecinie

  19. Fabrication and multimodal imaging of hybrid lyotropic liquid crystal structures such as myelin with the use of nanopart...

    Call: OPUS 28 , Panel: ST5

    Principal investigator: prof. Katarzyna Magdalena Matczyszyn

    Politechnika Wrocławska

  20. AI-based model for fast and label-free identification of BAALC overexpression in acute myeloid leukemia cells

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Paulina Małgorzata Laskowska

    Instytut Hematologii i Transfuzjologii

  21. The role of miRNAs (miR30a, miR30b, miR30c) in RARγ expression in acute myeloid leukemia (AML)

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Rafał Skopek

    Instytut Genetyki i Hodowli Zwierząt Polskiej Akademii Nauk

  22. Characteristics of anti-lipid IgG antibodies in patients with relapsing-remitting multiple sclerosis: physico-chemical p...

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Anna Izabela Jakubiak-Augustyn

    Uniwersytet Wrocławski

  23. The novel role of CD44 protein in the bone marrow microenvironment-mediated metabolic remodeling of chronic myeloid leuk...

    Call: PRELUDIUM 22 , Panel: NZ3

    Principal investigator: Laura Anna Turos-Korgul

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  24. Differences in the glycoproteomic profile of acute myeloid leukemia (AML) between cytogenetic and risk groups according ...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Tomasz Pieńkowski

    Uniwersytet Medyczny w Białymstoku

  25. Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Angelika Muchowicz

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  26. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr hab. Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  27. Development and differentiation of early-stage" myeloid-derived suppressor cells (e-MDSCs) in colorectal cancer – the ro...

    Call: OPUS 24 , Panel: NZ6

    Principal investigator: dr hab. Jarosław Tomasz Baran

    Uniwersytet Jagielloński, Collegium Medicum

  28. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  29. The role of the gut microbiota in the pathogenesis of plasma cell dyscrasias

    Call: PRELUDIUM 21 , Panel: NZ6

    Principal investigator: Marcin Mateusz Jasiński

    Warszawski Uniwersytet Medyczny

  30. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  31. Raman reporters as a tool to evaluate in vitro myeloid precursors differentiation.

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: dr Adriana Justyna Adamczyk

    Uniwersytet Jagielloński, Wydział Chemii

  32. Mechanisms of generation of myeloid-derived suppressor cells of monocyte origin (Mo-MDSCs) by extracellular vesicles fro...

    Call: PRELUDIUM 20 , Panel: NZ6

    Principal investigator: Izabela Siemińska

    Uniwersytet Jagielloński, Collegium Medicum

  33. Verification of personalized therapeutic strategy based on Integrated Stress Response inhibition for myeloid neoplasms w...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  34. Uracil in DNA and aberrant DNA methylation/hydroxymethylation as a new biomarkers of multiple myeloma development? A sea...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: prof. Ryszard Oliński

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  35. The proangiogenic functions of PIM kinases in plasma cell myeloma

    Call: ETIUDA 8 , Panel: NZ5

    Principal investigator: Filip Aleksander Garbicz

    Instytut Hematologii i Transfuzjologii

  36. The alterations in oligodendrocyte functioning in pathogenesisis of white matter injury resulting from neonaal asphyxia.

    Call: ETIUDA 8 , Panel: NZ4

    Principal investigator: Justyna Janowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  37. Identifying the hematopoietic and leukemic stem cell niches

    Call: MOZART 1 , Panel: NZ3

    Principal investigator: dr Krzysztof Szade

    Uniwersytet Jagielloński

  38. Linking stress response with genomic instability in chronic myeloid leukaemia cells; role of the PERK-eIF2α phosphorylat...

    Call: OPUS 1 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  39. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  40. Role of the human RNA exosome catalytic subunit DIS3 in multiple myeloma pathogenesis and cell physiology.

    Call: MAESTRO 1 , Panel: NZ1

    Principal investigator: prof. Andrzej Stanisław Dziembowski

    Uniwersytet Warszawski, Wydział Biologii

  41. Epigenetic effect on therapeutic activities of all-trans-retinoic acid in acute myeloid leukemia

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Arthur Zygmunt Zelent

    Instytut Genetyki i Hodowli Zwierząt Polskiej Akademii Nauk

  42. Identification, phenotypic and functional analysis of myeloid-derived suppressor cells in ovarian cancer in terms of the...

    Call: ETIUDA 7 , Panel: NZ5

    Principal investigator: dr Karolina Okła

    Uniwersytet Medyczny w Lublinie

  43. How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

    Call: SONATINA 3 , Panel: NZ2

    Principal investigator: dr Tomasz M. Kuliński

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  44. Immunological and molecular characteisitics of chronic myeloid leukemia patients after stopping imatinib

    Call: OPUS 16 , Panel: NZ6

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  45. The role of PIM kinases in the vascular niche of multiple myeloma

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Filip Aleksander Garbicz

    Instytut Hematologii i Transfuzjologii

  46. Multi-omics profiling of circulating myeloid-derived suppressor cells (cMDSCs) in epithelial ovarian cancer

    Call: PRELUDIUM 16 , Panel: NZ2

    Principal investigator: dr Karolina Okła

    Uniwersytet Medyczny w Lublinie

  47. Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

    Call: SONATA BIS 8 , Panel: NZ2

    Principal investigator: dr hab. Michał Marek Mikula

    Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

  48. Tracing the roots of leukemia - how preleukemic hematopoietic stem cells contribute to acute lymphoid and myeloid leukem...

    Call: HARMONIA 10 , Panel: NZ5

    Principal investigator: dr Krzysztof Tomasz Szade

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  49. Determining the role of basigin in multiple myeloma and acute myeloid leukaemia development

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Piotr Stanisław Łacina

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  50. Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Tadeusz Franciszek Kubicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski