Projects funded by the NCN


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81 projects found matching your search criteria :

  1. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Annamaria Teresa Lubelska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  2. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Antonina Malawska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  3. Role of prion protein in amyloidogenesis and neurotoxicity of Tau protein

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: dr hab. Krzysztof Nieznański

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. Interactions of amyloid beta peptides with metal ions and lipid membranes: Insights from lattice and all-atom simulation...

    Call: OPUS 10 , Panel: ST4

    Principal investigator: prof. Mai Suan Li

    Instytut Fizyki PAN

  5. Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Młyniec

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  6. Structure and function of Glod4 protein

    Call: PRELUDIUM 9 , Panel: NZ3

    Principal investigator: Olga Małgorzata Utyro

    Instytut Chemii Bioorganicznej PAN

  7. Assessment of the state and function of the brain cholinergic system in animal models of Alzheimer-type and frontotempor...

    Call: OPUS 8 , Panel: NZ4

    Principal investigator: dr hab. Grażyna Niewiadomska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  8. Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in ...

    Call: SONATA 8 , Panel: NZ4

    Principal investigator: dr Anna Mietelska-Porowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  9. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: dr hab. Robert Piotr Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  10. Approach to structures of difficult protein targets using new mass spectrometry-based methods

    Call: MAESTRO 6 , Panel: NZ1

    Principal investigator: prof. Michał Lech Dadlez

    Instytut Biochemii i Biofizyki PAN

  11. The influence of nanoparticles on beta-amyloid removal by microglia cells

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Katarzyna Sikorska

    Instytut Chemii i Techniki Jądrowej

  12. Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

    Call: HARMONIA 5 , Panel: NZ1

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

  13. Conjugates of prion protein with dendrimers as inhibitors of Abeta peptide amyloidogenesis and cytotoxicity of potential...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Krzysztof Nieznański

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  14. Searching for biological functions of APP family of proteins and APP-derived fragments in olfactory system.

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: dr hab. Rafał Tomasz Butowt

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  15. The influence of dimethyl fumarate on the spatial memory, neurogenesis, neurodegeneration and cerebral imflammation in t...

    Call: SONATA 5 , Panel: NZ4

    Principal investigator: dr Irena Maria Majkutewicz

    Uniwersytet Gdański, Wydział Biologii

  16. Structural investigation of the active center of gamma-secretase and its interactions with selected substrates.

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Krzysztof Młynarczyk

    Uniwersytet Warszawski, Wydział Chemii

  17. FUNCTIONAL STUDIES OF RARE GENETIC VARIANTS OF GENES CAUSSALLY CONNECTED WITH ALZHEIMER'S DISEASE IN THE POLISH POPULATI...

    Call: SONATA 5 , Panel: NZ3

    Principal investigator: dr Michalina Maria Wężyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  18. Looking for the same pathological factors in ischemic brain and Alzheimer's disease;Genes

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Ryszard Pluta

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  19. Synthetic cysteine peptides as molecular layers for studies of interactions between copper ions and beta-amyloid

    Call: SONATA 4 , Panel: ST4

    Principal investigator: dr Urszula Elżbieta Wawrzyniak

    Politechnika Warszawska, Wydział Chemiczny

  20. Determination of physicochemical and biochemical propertiess of natural pyridine and piperidine alkaloids and their simp...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: dr Damian Andrzej Szczesny

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  21. Search of novel multifunctional ligands targeting neurodegereneration processes.

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Barbara Antonina Malawska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  22. Functional, epigenetic and genetic aspects of base excision repair pathway in Alzheimer's disease

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  23. The role of acquired channelopathies in facilitationg post-traumatic epileptogenesis in APP/PS1 transgenic mice - an ani...

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Diana Miszczuk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  24. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Bernard Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  25. Synthesis and biological activity evaluation of new hybrid derivatives of tacrine and melatonin as potential cholinester...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Anna Zawadzka

    Uniwersytet Warszawski, Wydział Chemii

  26. The role of CDK5 in inflammatory reaction in experimental model of Alzheimer's disease

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  27. Role of Amyloid Precursor Protein in the regulation of store-operated calcium entry

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr Tomasz Sebastian Węgierski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  28. Transgenic mice with elevated basal level of calcium ions in neurons as a model of aged-induced neurodegeneration of spo...

    Call: MAESTRO 1 , Panel: NZ3

    Principal investigator: prof. Jacek Marceli Kuźnicki

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  29. Defining the mechanism of GSK3 dependent regulation of mTOR kinase activity in neurons in physiology and pathology.

    Call: PRELUDIUM 1 , Panel: NZ3

    Principal investigator: Małgorzata Barbara Urbańska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  30. Inhibitors, protein aggregation and carbon nanotube

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: dr hab. Mai Suan Li

    Instytut Fizyki PAN

  31. Normal021falsefalsefalseMicrosoftInternetExplorer4/* Style Definitions */table.MsoNormalTable{mso-style-name:Standardowy...

    Call: PRELUDIUM 1 , Panel: NZ2

    Principal investigator: dr Maciej Suski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski