Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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HCN channel functions in EEG synchronization and memory formation in a rat model of AD

2017/26/D/NZ4/00159

Keywords:

theta rhythm EEG Alzheimer's disease memory HCN channels

Descriptors:

  • NZ4_7:
  • NZ5_4:
  • NZ4_2:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paulina Dominika Kaźmierska-Grębowska 

Number of co-investigators in the project: 7

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 1 034 844 PLN

Project start date (Y-m-d): 2018-03-27

Project end date (Y-m-d): 2024-03-26

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (2)
  1. GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation
    Authors:
    Urbanska M, Kazmierska-Grebowska P, Kowalczyk T, Caban B, Nader K, Pijet B, Kalita K, Gozdz A, Devijver H, Lechat B, Jaworski T, Grajkowska W, Sadowski K, Jozwiak S, Kotulska K, Konopacki J, Van Leuven F, van Vliet EA, Aronica E, Jaworski J.
    Academic press:
    EBioMedicine (rok: 2019, tom: 39, strony: 377-387), Wydawca: Lancet
    Status:
    Published
    DOI:
    10.1016/j.ebiom.2018.11.040 - link to the publication
  2. Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations
    Authors:
    Paulina Kazmierska-Grebowska, Maciej M Jankowski, M Bruce MacIver
    Academic press:
    Aging and Disease (rok: 2024, tom: 1, strony: 22-42), Wydawca: International Society on Aging and Disease
    Status:
    Published
    DOI:
    10.14336/AD.2023.0607 - link to the publication
  3. Coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of GABAA receptors
    Authors:
    Hugo R. Arias, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Yaeun Shim, Bartosz Caban, Chloé Aman, Anne-Emilie Allain, Philippe De Deurwaerdère, Abdeslam Chagraoui
    Academic press:
    European Journal of Pharmacology (rok: 2024, tom: 0,890277777777778, strony: 176911), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2024.176911 - link to the publication
  4. Revisiting serotonin's role in spatial memory: A call for sensitive analytical approaches
    Authors:
    Paulina Kazmierska-Grebowska, Witold Żakowski, Dorota Myślińska, Ravindra Sahu, Maciej M. Jankowski
    Academic press:
    International Journal of Biochemistry and Cell Biology (rok: 2024, tom: 176, strony: 106663), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biocel.2024.106663 - link to the publication
  5. Lamotrigine Attenuates Neuronal Excitability, Depresses GABA Synaptic Inhibition, and Modulates Theta Rhythms in Rat Hippocampus
    Authors:
    Paulina Kazmierska-Grebowska, Marcin Siwiec, Joanna Ewa Sowa, Bartosz Caban, Tomasz Kowalczyk, Renata Bocian, M Bruce MacIver
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 45679), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222413604 - link to the publication
  1. Lamotrigine affects theta oscillations in the hippocampus of rats
    Authors:
    Bartosz Caban, Joanna E. Sowa, Marcin Siwiec, Renata Bocian, Tomasz Kowalczyk, Paulina Kaźmierska-Grębowska.
    Conference:
    14th International Congress of the Polish Neuroscience Society (rok: 2019, ), Wydawca: Acta Neurobiol Exp 2019, 79: I-XCIX
    Data:
    konferencja 28-30.08.2019
    Status:
    Published
  2. THETA OSCILLATIONS IN HIPPOCAMPAL FORMATION MAY DEPEND ON Ih CURRENT- AN IN VIVO AND IN VITRO APPROACH
    Authors:
    Paulina Kazmierska, Renata Bocian, Tomasz Kowalczyk, Joanna Ewa Sowa, Marcin Siwiec, Jan Konopacki
    Conference:
    The 41st Annual Meeting of the Japan Neuroscience Society (rok: 2018, ), Wydawca: Japan Neuroscience Society
    Data:
    konferencja 2018
    Status:
    Published

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