Projects funded by the NCN

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68 projects found matching your search criteria :

  1. MIST: Artificial intelligence-assisted design of experiments as a tool to streamline the development of siRNA-lipid nano...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr hab. Paulina Krystyna Skupin-Mrugalska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  2. Developing an AI algorithm for longitudinal tracking of post-treatment changes in brain metastases using a hybrid Uncert...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Monika Żaneta Pytlarz

    Sano - Centrum Zindywidualizowanej Medycyny Obliczeniowej - Międzynarodowa Fundacja Badawcza

  3. The JAK/STAT pathway as a molecular contributor to the development of endometriosis: therapeutic potential of JAK inhibi...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Aleksander Radosław Rycerz

    Uniwersytet Medyczny w Łodzi

  4. CTC-on-CAM: a platform for studying heterogeneity, epithelial-mesenchymal transition, and therapeutic sensitivity of cir...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: prof. Marek Arkadiusz Murias

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  5. Antibacterial molecules based on bacteriophage proteins and constant antibody fragments with therapeutic potential for t...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Karolina Aleksandra Filik-Matyjaszczyk

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  6. Modulating Neuroplasticity with Psilocybin: Assesment Therapeutic Potential in Treating Fentanyl use disorder

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Ewa Taracha

    Instytut Psychiatrii i Neurologii

  7. Porous bioglass-alginate composite granules as the antibiotic delivery system with therapeutic and regenerative potentia...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Adrian Szewczyk

    Gdański Uniwersytet Medyczny

  8. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Emilia Marcinkowska

    Uniwersytet Jagielloński

  9. Improving the therapeutic potential of cytostatics through the use of abiotic metallacarboranes.

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Michalina Gos

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  10. Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi

  11. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  12. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  13. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Jun Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  14. Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for ...

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Monika Bzowska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

  15. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii PAN

  16. Therapeutic self-understanding

    Call: SONATA 18 , Panel: HS1

    Principal investigator: dr Jędrzej Piotr Grodniewicz

    Uniwersytet Jagielloński, Centrum Kopernika Badań Interdyscyplinarnych Uniwersytetu Jagiellońskiego

  17. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  18. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  19. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  20. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii PAN

  21. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Tadeusz Piotr Karcz

    Uniwersytet Jagielloński, Collegium Medicum

  22. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  23. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Anna Wardowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  24. Non-provitamin A carotenoids as a novel therapeutic strategy in intestinal failure associated liver disease (IFALD)

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Maciej Jan Stawny

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  25. efFect of nanoscale, three dimensIonal arrangement of proteins on biological and Therapeutic activity (FIT)

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr Antonina Naskalska

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  26. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  27. Effect of SSR 504734, a selective glycine transporter type 1 inhibitor, on seizure activity and therapeutic efficacy of ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Piotr Wiktor Wlaź

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  28. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  29. Immunogenicity of plant-produced chimeric Virus-Like Particles formed byHBcAg displaying HBsAg epitopes for potential th...

    Call: POLS , Panel: NZ7

    Principal investigator: dr Benita Ortega Berlanga

    Instytut Genetyki Roślin PAN

  30. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  31. Improving the healing potential of therapeutic proteins by planned, specific modifiactions on the example of bacteriolyt...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: Marek Harhala

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  32. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii PAN

  33. Exploring the role and therapeutic potential of sex hormone binding globulin (SHBG) in the course of insulin resistance,...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Krzysztof Mariusz Marycz

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biologii i Hodowli Zwierząt

  34. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  35. Curcuminoid-polyphenol conjugates as potential therapeutics for urinary system cancer treatment

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  36. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  37. Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: dr Renata Joanna Grzela

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  38. Gut microbiota dependent modulation of therapeutic response and side effects to irinotecan and new camptothecin analogue...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jerzy Zygmunt Ostrowski

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  39. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Agata Siwek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  40. Evaluation of therapeutic role of novel positive allosteric modulators of GABA-A receptor in ischemic brain stroke

    Call: SONATA BIS 8 , Panel: NZ7

    Principal investigator: dr Monika Emilia Marcinkowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

  41. Bifunctional silica composites for bone tissue - therapeutic and regenerative implication

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: dr hab. Magdalena Urszula Prokopowicz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  42. New Hexokinase II inhibitors, in search of innovative therapeutic approaches to cancer treatment

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Mateusz Dawid Tomczyk

    Politechnika Śląska, Wydział Chemiczny

  43. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  44. New usnic acid derivatives as anticancer therapeutics

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Anna Herman-Antosiewicz

    Uniwersytet Gdański, Wydział Biologii

  45. Peroxiredoxins as potential therapeutic targets in glioblastoma.

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Monika Paulina Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  46. Cannabidiol as potential therapeutic agent for psoriasis and its role in the stabilization of physiological level of lip...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Elżbieta Skrzydlewska

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  47. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Michał Karol Załuski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  48. Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Marek Wojciech Bajda

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  49. Modulation of the expression and activation of transcription factors Nrf2 and NF-kappaB by new synthetic triterpenoids a...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Wanda Maria Baer-Dubowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  50. Biased inverse agonists of 5-HT6 receptor and dual 5-HT6/MAO-B inhibitors - in search for new therapeutic approaches for...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

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