Projects funded by the NCN
Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therapeutic implications
2021/43/D/NZ7/03366
Keywords:
platelet aggregation and adhesion thrombin generation tromboxane A2 integrin αIIbβ3 extracellular vesicles
Descriptors:
- NZ7_014:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: SONATA 17 - announced on 2021-09-15
Amount awarded: 1 657 204 PLN
Project start date (Y-m-d): 2022-08-03
Project end date (Y-m-d): 2025-08-02
Project duration:: 36 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Protein disulfide isomerase 1 (PDIA1) regulates platelet-derived extracellular vesicle releaseAuthors:Agnieszka Pelesz ,Katarzyna Rafa-Zablocka, Patrycja Kaczara, Stefan Chlopicki, Kamil PrzyborowskiAcademic press:Thrombosis Research (rok: 2025, tom: 245:109209, strony: 45668), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.thromres.2024.109209 - link to the publication