Projects funded by the NCN


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169 projects found matching your search criteria :

  1. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Burchacka

    Politechnika Wrocławska

  2. Hijacking the ubiquitin-proteasome system by the UL49.5 protein of bovine herpesvirus 1 as an immune evasion strategy – ...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: Magda Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  3. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  4. Effect of vitamin D3 supplementatioin of pigs diet on transcriptome and proteome in selected tissues.

    Call: PRELUDIUM BIS 1 , Panel: NZ9

    Principal investigator: dr hab. Maria Oczkowicz

    Instytut Zootechniki - Państwowy Instytut Badawczy

  5. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  6. Cellular adaptation to cold.

    Call: GRIEG 1 , Panel: NZ3

    Principal investigator: dr Wojciech Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  7. Preventing the accumulation of cytotoxic oligomers, that are causative agents of neurodegenerative diseases and Type 2 D...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  8. Effects of proteasome inhibition on mitochondrial homeostasis.

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Agnieszka Chacińska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  9. Analysis of SWI/SNF complexes in Arabidopsis and of their activity's regulation through 26S proteasome with special cons...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Anna Rolicka

    Uniwersytet Warszawski, Wydział Biologii

  10. Epigenetic regulation of pro-epileptic protease Matrix Metalloproteinase-9 expression in the hippocampus during epilepto...

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: dr hab. Marcin Rylski

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  11. Doubly knotted proteins - frontiers of topological complexity of proteins

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr hab. Joanna Sułkowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  12. Anisakis simplex as a parasite of public health importance: transcriptome and proteome as a source of information on the...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: prof. Iwona Bogacka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  13. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  14. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

    Call: OPUS 16 , Panel: NZ5

    Principal investigator: prof. Marzena Gajęcka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  15. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  16. Mechanisms of host-pathogen interaction in the immune response of Galleria mellonella after infection with entomopathoge...

    Call: OPUS 1 , Panel: NZ6

    Principal investigator: dr hab. Iwona Wojda

    Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

  17. Dissecting the proteolytic fingerprint of breast cancer tissues using mass cytometry for personalized oncology.

    Call: SONATA 14 , Panel: NZ5

    Principal investigator: dr Marcin Poręba

    Politechnika Wrocławska

  18. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska

  19. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  20. Integrated transcriptomic, proteomic and metabolomic analysis of molecules that mediate homing of mesenchymal stem cells...

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Agnieszka Piekiełko-Witkowska

    Centrum Medyczne Kształcenia Podyplomowego

  21. Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Tadeusz Kubicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  22. Chemerin - a new regulator of the porcine corpus luteum during the oestrous cycle

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Edyta Rytelewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  23. The effect of peroxisome proliferator-activated receptor gamma (PPARy) ligands on the transrciptome and proteome profile...

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Zuzanna Kunicka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  24. Functional and structural interplay between two mitochondrial inner membrane proteases, AtFTSH4 and AtOMA1, in Arabidops...

    Call: OPUS 14 , Panel: NZ2

    Principal investigator: prof. Hanna Jańska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  25. Cellular proteases during coronaviral infection

    Call: OPUS 14 , Panel: NZ6

    Principal investigator: dr hab. Krzysztof Pyrć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  26. Features of human serum proteome involved in response to ionizing radiation

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Piotr Widłak

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

  27. Novel inhibitors of herpes virus protease

    Call: PRELUDIUM 14 , Panel: NZ6

    Principal investigator: Magdalena Pachota

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  28. Role of proteasome in the regulation of Gli protein activity by the Hedgehog pathway

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr hab. Paweł Niewiadomski

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  29. Toward understanding allosteric regulation of the proteasome activity

    Call: OPUS 1 , Panel: ST5

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  30. Biodegradation of nitrofuranes derivatives by environmental bacteria - from metabolic pathways to proteome and genome mo...

    Call: OPUS 14 , Panel: NZ9

    Principal investigator: prof. Ewa Kaczorek

    Politechnika Poznańska, Wydział Technologii Chemicznej

  31. Tear film proteome in age related macular degeneration (AMD) patients.

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Mateusz Winiarczyk

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  32. Determination of arginase-1 as a potential drug target in the treatment of multiple myeloma and in reducing proteasome i...

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Jakub Gołąb

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  33. Sperm proteomic approach as the way to delineate a leading course of asthenozoospermia

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: prof. Maciej Kurpisz

    Instytut Genetyki Człowieka PAN

  34. Proteomic analysis of myeloma plasma cells to determine proteins and pathways involved in acquired resistance to proteas...

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr hab. Dominik Dytfeld

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  35. Identification and therapeutic use of proteasome machinery targets in human cancer

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr Dawid Walerych

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  36. The development of classic and aggregation- induced emission activity- based probes for human caspases.

    Call: PRELUDIUM 13 , Panel: ST5

    Principal investigator: Katarzyna Groborz

    Politechnika Wrocławska

  37. An integrated screening platform for determination of human proteasomes extended substrate specificity

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska

  38. SLPI-dependent cutaneous antimicrobial and antiviral immunity.

    Call: OPUS 13 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  39. The structural and functional characterization of Tpr, calpain-like peptidase and important virulence factor of Porphyro...

    Call: PRELUDIUM 13 , Panel: NZ1

    Principal investigator: dr Dominika Staniec

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. Environmental factors and the evolution of chemical communication in turtles - a phylogenetic perspective

    Call: OPUS 13 , Panel: NZ8

    Principal investigator: dr Alejandro Ricoma

    Uniwersytet Jagielloński, Wydział Biologii

  41. Allosteric inhibitors of proteasome - optimization of the structure of PR39 analogs in order to achieve greater efficien...

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Małgorzata Giżyńska

    Uniwersytet Gdański, Wydział Chemii

  42. Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors...

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Tadeusz Robak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  43. SLPI - novel regulator involved in the neuro-immune interplay in psoriasis

    Call: SONATA 12 , Panel: NZ6

    Principal investigator: dr Beata Grygier

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  44. Searching for specific signatures of predominant, primary glomerulopathies by employing global transcriptomic and proteo...

    Call: SONATA 12 , Panel: NZ5

    Principal investigator: dr Karolina Marek-Bukowiec

    Wojewódzki Szpital Specjalistyczny we Wrocławiu. Ośrodek Badawczo-Rozwojowy

  45. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Katherine Falkowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  46. Autophagy and ubiquitin-proteasome system as potential mechanisms responsible for left ventricle mass loss in a monocrot...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Mateusz Hołda

    Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

  47. The effect of crowded environment on the catalytic activity and dynamics of viral proteases

    Call: OPUS 12 , Panel: NZ1

    Principal investigator: prof. Joanna Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  48. Integrated analysis of transcriptome and proteome as a tool for assessment of quality and ageing process in eggs of pike...

    Call: HARMONIA 8 , Panel: NZ9

    Principal investigator: dr Daniel Żarski

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Bioinżynierii Zwierząt

  49. In vivo role of transient ECM protease activity in synaptic plasticity

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: Marta Magnowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

  50. Physiological characterization of the HtrA4 protease, including its role in apoptosis.

    Call: PRELUDIUM 11 , Panel: NZ3

    Principal investigator: dr Tomasz Wenta

    Uniwersytet Gdański, Wydział Biologii