Projects funded by the NCN
Participation of cellular proteins in the inhibition of antigen presentation dependent on UL49.5 protein of bovine herpesvirus BHV-1
2020/36/T/NZ3/00100
Keywords:
ERAD ubiquitin protein degradation proteasome TAP MHC I
Descriptors:
- NZ3_1: Cell biology
- NZ6_5: Virology
- NZ1_1: Molecular biology
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 1
Call: ETIUDA 8 - announced on 2019-12-16
Amount awarded: 139 352 PLN
Project start date (Y-m-d): 2020-10-01
Project end date (Y-m-d): 2022-03-31
Project duration:: 18 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradationAuthors:Magda Wąchalska, Celeste Riepe, Magdalena J. Ślusarz, Małgorzata Graul, Lukasz S. Borowski, Wenjie Qiao, Michalina Foltyńska, Jan E. Carette, Krystyna Bieńkowska-Szewczyk, Roman J. Szczesny, Ron R. Kopito, Andrea D. LipińskaAcademic press:Proceedings of the National Academy of Sciences (PNAS) (rok: 2024, tom: 121, strony: -), Wydawca: PNASStatus:PublishedDOI:10.1073/pnas.2309841121 - link to the publication