Projects funded by the NCN

New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Krzysztof Walczak

Politechnika Śląska, Wydział Chemiczny

Nanotheranostics dedicated to targeted anticancer therapies: Novel magnetic hybrid carbon-based materials - synthesis an...

Call: PRELUDIUM 11 , Panel: ST5

Principal investigator: Artur Kasprzak

Politechnika Warszawska, Wydział Chemiczny

Hypoxia compensation into physioxia to normalize/regenerate ischaemc tissues. Effects of microRNA regulation for targete...

Call: OPUS 12 , Panel: NZ1

Principal investigator: prof. Claudine Kieda

Wojskowy Instytut Medyczny

The role of insulin signaling in melanoma maintenance and response to targeted therapeutics

Call: PRELUDIUM 13 , Panel: NZ3

Principal investigator: Marta Osrodek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Marta Spodzieja

Uniwersytet Gdański, Wydział Chemii

CD73 (ecto-5'-nucleotidase) function in breast cancer progression and promotion, and its assessment as a therapeutic tar...

Call: OPUS 14 , Panel: NZ5

Principal investigator: dr hab. Patrycja Koszałka

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Determination of targets for peptidylarginine deiminase type 4 (PAD4) among complement system proteins and assessment of...

Call: HARMONIA 10 , Panel: NZ1

Principal investigator: dr Ewa Bielecka

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

The Development of a Targeted MRI Contrast Agent for Early Diagnosis of Prostate Cancer.

Call: HARMONIA 10 , Panel: NZ5

Principal investigator: Barbara Błasiak

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

Antiparasitic properties and molecular target identification of new thiosemicarbazide and thiazolidinone derivates in To...

Call: PRELUDIUM 16 , Panel: NZ6

Principal investigator: Adrian Bekier

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Regulation of ALKBH proteins expression in cancer and its role in cancer therapy.

Call: OPUS 2 , Panel: NZ4

Principal investigator: prof. Elżbieta Grzesiuk

Instytut Biochemii i Biofizyki PAN

Characterization of CD44/p53 signaling involved in the CD44-dependent cancer stem cells: small molecules and peptides, t...

Call: MAESTRO 3 , Panel: ST5

Principal investigator: prof. Tadeusz Holak

Uniwersytet Jagielloński, Wydział Chemii

Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets ...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Physicochemical characterization of cyclodextrins tailored for pH-dependent targeted therapy with anthracycline drugs

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Renata Bilewicz

Uniwersytet Warszawski, Wydział Chemii

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Purine salvage pathway enzymes as a target for pathogenic organisma lacking de novo purine synthesis -cas study of Helic...

Call: HARMONIA 7 , Panel: NZ1

Principal investigator: prof. Maria Bzowska

Uniwersytet Warszawski, Wydział Fizyki

The participation of low-molecular regulatory RNAs and their target genes in the development of generative organs in yel...

Call: SONATA 10 , Panel: NZ9

Principal investigator: dr Paulina Glazińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

Identifying molecular events for transformation of early colorectal polyps. Studies with APC1311-targeted pigs.

Call: SONATA 11 , Panel: NZ2

Principal investigator: dr hab. Monika Dragan

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Call: MAESTRO 12 , Panel: NZ3

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Functional framework for viral RNA-dependent RNA polymerase, a major target in COVID19 treatment

Call: Polskie Powroty NAWA 2020 COVID-19 , Panel: NZ1

Principal investigator: dr Tomasz Wojciech Turowski

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Molecular and cellular landscape of pulmonary and hepatic metastases of colorectal cancer with potential clinical implic...

Call: PRELUDIUM 20 , Panel: NZ4

Principal investigator: dr Marta Aleksandra Popęda

Gdański Uniwersytet Medyczny, Wydział Lekarski

Searching for new therapeutic targets in polyglutamine diseases

Call: OPUS 22 , Panel: NZ2

Principal investigator: dr hab. Marta Olejniczak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Multiomic characterization of neurogenerative processes in Zebrin-II positive and Zebrin-II negative Purkinje cells

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Grażyna Adamek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Two-body currents in the electron and neutrino scattering off few-nucleon targets

Call: IMPRESS-U , Panel: ST2

Principal investigator: prof. Jacek Golak

Uniwersytet Jagielloński

Targeted drug delivery systems - synthesis and functionalization of nanocarriers

Call: SONATA 2 , Panel: ST5

Principal investigator: dr Krzysztof Szczepanowicz

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Oligomer-Focused Screening and Individualized Therapeutics to target Neurodegenerative Disorders

Call: JPND2019 , Panel: NZ1

Principal investigator: dr Piotr Hańczyc

Uniwersytet Warszawski

Novel aspects of virulence mechanisms of HopBF1, a bacterial effector that targets host HSP90 protein

Call: OPUS 19 , Panel: NZ1

Principal investigator: dr hab. Magdalena Krzymowska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Bioinspired materials science: Poriferan Chitin as multi-target scaffolding biomaterial

Call: OPUS 19 , Panel: ST5

Principal investigator: prof. Hermann Ehrlich

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

On the way to elucidate the effects of cannabidiol (CBD) on living organisms - assessment of changes in the global trans...

Call: PRELUDIUM BIS 2 , Panel: NZ9

Principal investigator: dr hab. Artur Gurgul

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Ośrodek Medycyny Eksperymentalnej i Innowacyjnej

Enzymes of the L-methionine biosynthetic pathway as novel moleculartargets for antifungal chemotherapy

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Structural and functional studies of the plant enzymes of arginine metabolism as molecular targets of novel plant protec...

Call: SONATA 17 , Panel: NZ1

Principal investigator: dr Bartosz Sekuła

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Feasibility study and experimental verification of the LHC beam halo splitting layout with bent crystals for the ALICE f...

Call: SONATA 17 , Panel: ST2

Principal investigator: dr Marcin Patecki

Politechnika Warszawska

Functional Characterization of Non-Collagenous Extracellular Matrix Proteins as a Potential Molecular Target and Novel B...

Call: SONATA 8 , Panel: NZ5

Principal investigator: dr Michał Pawlak

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

RNA structure prediction based on modeling the target sequence and homologous sequences

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: Marcin Magnus

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Experiment COMPASS - study of the three-dimensional and spin structure of the nucleon

Call: HARMONIA 7 , Panel: ST2

Principal investigator: prof. Andrzej Sandacz

Narodowe Centrum Badań Jądrowych

High throughput determination of RNA targets for MBNL1 splicing factor - Implication for myotonic dystrophy

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza, Wydział Biologii

Synthesis of new phthalocyanines for targeted photodynamic cancer therapy.

Call: SONATA 2 , Panel: ST5

Principal investigator: dr Łukasz Łapok

Uniwersytet Jagielloński, Wydział Chemii, Zespół Nanotechnologii Polimerów i Biomateriałów

Studies on non-linear laser-plasma interactions and generation of shocks in plasma for shock ignition of inertially conf...

Call: HARMONIA 2 , Panel: ST2

Principal investigator: prof. Jan Badziak

Instytut Fizyki Plazmy i Laserowej Mikrosyntezy im. Sylwestra Kaliskiego

Bioconjugates of 103Pd nanostructures for targeted Auger electron therapy.

Call: OPUS 23 , Panel: ST5

Principal investigator: dr hab. Agnieszka Majkowska-Pilip

Instytut Chemii i Techniki Jądrowej

Senolytic nanoplatform to target and eliminate skin cancer Zombie cells

Call: M-ERA.NET 3 Call 2022 , Panel: ST5

Principal investigator: dr hab. Anna Lewińska

Uniwersytet Rzeszowski

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

Call: OPUS 26 (LAP) , Panel: NZ7

Principal investigator: dr Anna Czarna

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Stimuli-responsive anion transporters for targeted drug delivery

Call: OPUS 26 , Panel: ST5

Principal investigator: dr hab. Michał Chmielewski

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of ...

Call: MAESTRO 8 , Panel: NZ2

Principal investigator: prof. Piotr Kozłowski

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Molecular background of brain metastases in lung cancer

Call: SONATA 12 , Panel: NZ2

Principal investigator: dr Marcin Nicoś

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Bacterial toxin-antitoxin systems as novel target for the development of potential antibiotics

Call: PRELUDIUM 13 , Panel: NZ1

Principal investigator: dr Marcin Równicki

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Identification of nuclear function of Arabidopsis Target of Rapamycin protein

Call: PRELUDIUM 13 , Panel: NZ2

Principal investigator: Paweł Ćwiek

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Prohepcidin as a molecular target of cadmium binding

Call: PRELUDIUM 16 , Panel: ST4

Principal investigator: Dawid Płonka

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Steady states in confined microscopic systems: auxetic micro-slits and stimuli sensitive microgel particles in microchan...

Call: OPUS 3 , Panel: ST3

Principal investigator: dr hab. Arkadiusz Brańka

INSTYTUT FIZYKI MOLEKULARNEJ PAN

Application of targeted next generation sequencing (NGS) in the identification of genetic markers associated with the po...

Call: SONATA 5 , Panel: NZ9

Principal investigator: dr Katarzyna Piórkowska

Instytut Zootechniki - Państwowy Instytut Badawczy