Projects funded by the NCN

Targeted inhibition of STATs and IRFs as a novel treatment strategy in cardiovascular disease

Call: OPUS 9 , Panel: NZ2

Principal investigator: prof. Johannes Bluijssen (Bluyssen)

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

Call: OPUS 9 , Panel: NZ6

Principal investigator: dr Iwona Gabriel

Politechnika Gdańska, Wydział Chemiczny

Translation elongation as a target for regulation by non-coding RNAs in bacteria

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr hab. Mikołaj Olejniczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea...

Call: UNISONO , Panel: NZ1

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Functional Characterization of Non-Collagenous Extracellular Matrix Proteins as a Potential Molecular Target and Novel B...

Call: SONATA 8 , Panel: NZ5

Principal investigator: dr Michał Pawlak

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Next-generation sequencing of miRNA transcriptome and functional in vitro study: towards unravelling pathomechanisms and...

Call: OPUS 8 , Panel: NZ2

Principal investigator: prof. Michał Witt

Instytut Genetyki Człowieka PAN

Approach to structures of difficult protein targets using new mass spectrometry-based methods

Call: MAESTRO 6 , Panel: NZ1

Principal investigator: prof. Michał Dadlez

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono...

Call: SONATA BIS 4 , Panel: ST5

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Identification of proline metabolic pathway as a molecular target for experimental regulation of apoptosis/autophagy in ...

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Jerzy Pałka

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Physicochemical characterization of cyclodextrins tailored for pH-dependent targeted therapy with anthracycline drugs

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Renata Bilewicz

Uniwersytet Warszawski, Wydział Chemii

Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms...

Call: SONATA 1 , Panel: NZ4

Principal investigator: dr Wojciech Placha

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

New drug carriers in targeted anticancer therapy

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Artur Terzyk

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Coupling of synthesis and transport for proteins targeted to the mitochondria

Call: OPUS 6 , Panel: NZ3

Principal investigator: prof. Agnieszka Chacińska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

Call: OPUS 6 , Panel: NZ7

Principal investigator: dr hab. Sylwia Flis

Narodowy Instytut Leków

Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

Call: OPUS 6 , Panel: NZ4

Principal investigator: dr hab. Jadwiga Wardas

Instytut Farmakologii Polskiej Akademii Nauk

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

BCL11b - Potential Therapeutic Target in T cell Neoplasms

Call: OPUS 5 , Panel: NZ1

Principal investigator: dr hab. Grzegorz Przybylski

Instytut Genetyki Człowieka PAN

The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

Call: OPUS 5 , Panel: NZ3

Principal investigator: prof. Joanna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Application of targeted next generation sequencing (NGS) in the identification of genetic markers associated with the po...

Call: SONATA 5 , Panel: NZ9

Principal investigator: dr Katarzyna Piórkowska

Instytut Zootechniki - Państwowy Instytut Badawczy

High throughput determination of RNA targets for MBNL1 splicing factor - Implication for myotonic dystrophy

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza, Wydział Biologii

Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets ...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Assessment of genetic basis of fear-related aggression in police dogs using the SNP microarrays technology and behaviour...

Call: SONATA 4 , Panel: NZ9

Principal investigator: dr Marta Walczak

Instytut Genetyki i Hodowli Zwierząt PAN

Characterization of CD44/p53 signaling involved in the CD44-dependent cancer stem cells: small molecules and peptides, t...

Call: MAESTRO 3 , Panel: ST5

Principal investigator: prof. Tadeusz Holak

Uniwersytet Jagielloński, Wydział Chemii

Identification of potential therapeutic targets in melanoma stem-like cells

Call: HARMONIA 3 , Panel: NZ2

Principal investigator: prof. Małgorzata Czyż

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Carbon nanotubes as magnetic nanocariers in the targeted chemotherapy

Call: SONATA 3 , Panel: ST5

Principal investigator: dr hab. Sławomir Boncel

Politechnika Śląska, Wydział Chemiczny

Steady states in confined microscopic systems: auxetic micro-slits and stimuli sensitive microgel particles in microchan...

Call: OPUS 3 , Panel: ST3

Principal investigator: dr hab. Arkadiusz Brańka

INSTYTUT FIZYKI MOLEKULARNEJ PAN

Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

Call: SONATA 3 , Panel: ST5

Principal investigator: dr Ewelina Zabost

Uniwersytet Warszawski, Wydział Chemii

Studies on non-linear laser-plasma interactions and generation of shocks in plasma for shock ignition of inertially conf...

Call: HARMONIA 2 , Panel: ST2

Principal investigator: prof. Jan Badziak

Instytut Fizyki Plazmy i Laserowej Mikrosyntezy im. Sylwestra Kaliskiego

Regulation of ALKBH proteins expression in cancer and its role in cancer therapy.

Call: OPUS 2 , Panel: NZ4

Principal investigator: prof. Elżbieta Grzesiuk

Instytut Biochemii i Biofizyki PAN

Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t...

Call: PRELUDIUM 2 , Panel: NZ1

Principal investigator: dr Anna Stachurska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Two-body currents in the electron and neutrino scattering off few-nucleon targets

Call: IMPRESS-U , Panel: ST2

Principal investigator: prof. Jacek Golak

Uniwersytet Jagielloński

Stimuli-responsive anion transporters for targeted drug delivery

Call: OPUS 26 , Panel: ST5

Principal investigator: dr hab. Michał Chmielewski

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Activation of Staphylococcus aureus LytM autolysin as a potential target for antimicrobials development.

Call: OPUS 26 , Panel: NZ1

Principal investigator: dr hab. Izabela Sabała

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Multiomic characterization of neurogenerative processes in Zebrin-II positive and Zebrin-II negative Purkinje cells

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Grażyna Adamek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Izabela Siekierska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

Call: SONATA 18 , Panel: NZ3

Principal investigator: dr Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Centrum Chorób Mózgu

Senolytic nanoplatform to target and eliminate skin cancer Zombie cells

Call: M-ERA.NET 3 Call 2022 , Panel: ST5

Principal investigator: dr hab. Anna Lewińska

Uniwersytet Rzeszowski

Gaining control on XBP1s signaling as a starting point for novel cancer therapies

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Rafał Bartoszewski

Uniwersytet Wrocławski, Wydział Biotechnologii

Targeted drug delivery systems - synthesis and functionalization of nanocarriers

Call: SONATA 2 , Panel: ST5

Principal investigator: dr Krzysztof Szczepanowicz

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Call: POLONEZ BIS 3 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Modifiers of Muscleblind-like genes expression in health and disease.

Call: SONATA BIS 12 , Panel: NZ5

Principal investigator: dr hab. Ewa Stępniak-Konieczna

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

Call: OPUS 23 , Panel: NZ4

Principal investigator: prof. Małgorzata Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Yeast DNA topoisomerase II as a model molecular target for novel antifungalcompounds

Call: OPUS 23 , Panel: NZ6

Principal investigator: dr hab. Iwona Gabriel

Politechnika Gdańska, Wydział Chemiczny

Synthesis of new phthalocyanines for targeted photodynamic cancer therapy.

Call: SONATA 2 , Panel: ST5

Principal investigator: dr Łukasz Łapok

Uniwersytet Jagielloński, Wydział Chemii, Zespół Nanotechnologii Polimerów i Biomateriałów

Bioconjugates of 103Pd nanostructures for targeted Auger electron therapy.

Call: OPUS 23 , Panel: ST5

Principal investigator: dr hab. Agnieszka Majkowska-Pilip

Instytut Chemii i Techniki Jądrowej

Feasibility study and experimental verification of the LHC beam halo splitting layout with bent crystals for the ALICE f...

Call: SONATA 17 , Panel: ST2

Principal investigator: dr Marcin Patecki

Politechnika Warszawska

Elucidating neurodegenerative processes using direct profiling of selectively vulnerable neurons

Call: SONATA 17 , Panel: NZ3

Principal investigator: dr Paweł Świtoński

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk