Projects funded by the NCN

Innovative approach to support healthy ageing: a multidirectional evaluation of the health-promoting potential of iodine...

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Katarzyna Karolina Krawczyk

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie

Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi...

Call: OPUS 29 , Panel: NZ2

Principal investigator: dr Estera Elmira Rintz

Uniwersytet Gdański

Addressing the fundamental discrepancy observed in sub-Doppler molecular spectra of the hydrogen molecule – development ...

Call: PRELUDIUM 24 , Panel: ST2

Principal investigator: Kamil Piotr Stankiewicz

Uniwersytet Mikołaja Kopernika

NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Arkadiusz Bogumił Leniak

Instytut Farmakologii PAN

Molecular factors and pathomechanism of cancer-associated cachexia.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marcin Tomasz Skrzypski

Gdański Uniwersytet Medyczny

Incorporation of local TiN thin films heterogeneities into the full-field hybrid fracture model based on the digital mat...

Call: OPUS 27 , Panel: ST8

Principal investigator: dr Konrad Perzyński

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Developmental neurotoxicity of nanoplastic. Functional, structural and molecular analysis of the neurovascular unit in t...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Kamil Dawid Adamiak

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

How to see the invisible? Dark plasmonic modes and dark electronic molecular states visualisation with Raman and lumines...

Call: SONATA BIS 13 , Panel: ST4

Principal investigator: dr Sylwester Gawinkowski

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Probing Nanoscale Molecular Mechanisms in Cystic Fibrosis through s-SNOM: From model to complex systems

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Tetiana Stepanenko

Uniwersytet Jagielloński, Narodowe Centrum Promieniowania Synchrotronowego SOLARIS

Size dependent mechanical behavior of cracked micro- and nanobeams: nonclassical modeling and experimental validation (a...

Call: SONATA 18 , Panel: ST8

Principal investigator: dr Hossein Darban

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Nonbenzenoid polycyclic aromatic hydrocarbons as molecular models of defected graphene

Call: SONATA 18 , Panel: ST4

Principal investigator: dr Bartłomiej Zygmunt Pigulski

Uniwersytet Wrocławski, Wydział Chemii

Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

Call: OPUS 23 , Panel: NZ4

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Yeast DNA topoisomerase II as a model molecular target for novel antifungalcompounds

Call: OPUS 23 , Panel: NZ6

Principal investigator: dr hab. Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Bacterial microdomain modeling for selected antimicrobial compounds interactions.

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: dr Mateusz Igor Rzycki

Politechnika Wrocławska

The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: dr Magdalena Białoń

Instytut Farmakologii PAN

Prediction-based normalization for developmental heterochrony in parallel molecular-level and phenomic studies in plants

Call: OPUS 22 (LAP) , Panel: NZ9

Principal investigator: prof. Paweł Bolesław Krajewski

Instytut Genetyki Roślin PAN

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Multilevel molecular analysis of the hepatoprotective effect of medicinal herbs extracts in prevention of liver dysfunct...

Call: OPUS 22 (LAP) , Panel: NZ9

Principal investigator: prof. Chandra Shekhar Pareek

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

The effect of mesenchymal and muscle stem /progenitor cells in the MDX dystrophic mouse model on the function and molecu...

Call: PRELUDIUM 20 , Panel: NZ3

Principal investigator: dr Magdalena Nowaczyk

Instytut Genetyki Człowieka PAN

Blood-brain barrier: A 3D cell model and its functionality assessed by a multimodal molecular platform.

Call: OPUS 21 , Panel: ST4

Principal investigator: dr hab. Kamilla Małek

Uniwersytet Jagielloński, Wydział Chemii

Molecular mechanisms of SDAV (Sialodacryoadenitis Virus) neuropathogenicity in an in vitro primary cell culture model of...

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: Michalina Maria Bartak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Differential roles of the HSPA1 and HSPA2 proteins from the human HSPA (HSP70) family of molecular chaperones in bronchi...

Call: PRELUDIUM BIS 2 , Panel: NZ4

Principal investigator: dr hab. Dorota Bogumiła Ścieglińska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Anna Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Molecular profiling of novel antipsychotic drug candidates

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Development of an in vitro model for the evaluation of phototoxicity of drugs with different affinity to melanin using a...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr hab. Jakub Rok

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

TUMORMAP: Mapping tumor subclones and their immune microenvironment in ultra-high spatial and molecular resolution

Call: SONATA BIS 10 , Panel: NZ2

Principal investigator: dr hab. Ewa Szczurek

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Spatial analysis of the effects of L-DOPA on gene expression in the prefrontal cortex in a mouse model of Parkinson's di...

Call: PRELUDIUM 19 , Panel: NZ4

Principal investigator: dr Anna Aleksandra Radlicka-Borysewska

Instytut Farmakologii PAN

Dry friction at the nanoscale: dependence on the sliding velocity and the loading force

Call: OPUS 19 , Panel: ST8

Principal investigator: dr hab. Arkadiusz Ptak

Politechnika Poznańska, Wydział Inżynierii Materiałowej i Fizyki Technicznej

To what extent the transcriptomic response in the events initiating lung toxicity in mice depends on the structural feat...

Call: OPUS 19 , Panel: ST5

Principal investigator: prof. Tomasz Puzyn

Uniwersytet Gdański, Wydział Chemii

Combination of Molecular Simulation and Deep Learning for De Novo Drug Design

Call: PRELUDIUM 19 , Panel: ST6

Principal investigator: dr Tomasz Jakub Danel

Uniwersytet Jagielloński, Wydział Matematyki i Informatyki

Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: dr Natalia Helena Bryniarska-Kubiak

Instytut Farmakologii PAN

Coarse-grained modeling of carbohydrates

Call: OPUS 18 , Panel: ST4

Principal investigator: dr hab. Wojciech Sylwester Płaziński

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

The effect of high fat and high carbohydrate diet on molecular profile of inflammation in animal model of obesity in ast...

Call: OPUS 18 , Panel: NZ5

Principal investigator: prof. Aleksandra Maria Szczepankiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

Call: OPUS 17 , Panel: NZ2

Principal investigator: dr Mateusz Kurciński

Uniwersytet Warszawski

Studies of molecular interactions and proton transfer in biological membranes and models by nanoscale vibrational spectr...

Call: OPUS 16 , Panel: NZ1

Principal investigator: dr hab. Luca Quaroni

Uniwersytet Jagielloński, Wydział Chemii

Cytogenomic analysis of key aspects of nuclear genome organisation in the polyploid model grass Brachypodium hybridum an...

Call: OPUS 16 , Panel: NZ3

Principal investigator: prof. Robert Hasterok

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Implementing molecular models for the HIV and HCV transmission networks and resisistance surveillance to inform clinical...

Call: SONATA BIS 8 , Panel: NZ6

Principal investigator: prof. Miłosz Parczewski

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Medycyny

Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

Call: SONATA BIS 8 , Panel: ST4

Principal investigator: dr Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Molecular mechanisms of signaling lipid recognition in the membrane: phosphatidic acid and ceramide-1-phosphate

Call: SONATA BIS 8 , Panel: NZ1

Principal investigator: dr hab. Aleksander Czogalla

Uniwersytet Wrocławski, Wydział Biotechnologii

Combining Rosetta method with deeply coarse grained SURPASS model into a novel multiscale algorithm for modeling protein...

Call: OPUS 15 , Panel: ST6

Principal investigator: dr hab. Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Molecular characterization of mitoferrins from model plant Arabidopsis thaliana

Call: PRELUDIUM 15 , Panel: NZ1

Principal investigator: Karolina Maria Małas

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Determination of mechanisms and critical molecular partners controlling the multidrug resistance proteins (P-gp and BCRP...

Call: OPUS 15 , Panel: NZ3

Principal investigator: dr hab. Marlena Godlewska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Studium Kliniczno-Dydaktyczne

Searching for behavioural and molecular predictors of long-term benzodiazepine administration in preclinical chronic str...

Call: SONATINA 2 , Panel: NZ7

Principal investigator: dr Karolina Anna Kołosowska

Instytut Psychiatrii i Neurologii

Understanding the molecular basis of the regulation of activity of lysosome, a potential target of therapeutic intervent...

Call: OPUS 14 , Panel: NZ3

Principal investigator: prof. Magdalena Angelina Gabig-Cimińska

Uniwersytet Gdański, Wydział Biologii

Molecular mechanism of anticancer action of selected NSAIDs as a PPAR gamma receptor agonists in experimental models of ...

Call: PRELUDIUM 14 , Panel: NZ7

Principal investigator: Adam Kazberuk

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Increasing global and local accuracy of the coarse-grained UNRES model of proteins and its extensions to simulating very...

Call: OPUS 13 , Panel: ST4

Principal investigator: prof. Józef Adam Liwo

Uniwersytet Gdański, Wydział Chemii

Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Małgorzata Gobis

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny