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Information of the project and the call

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The effect of high fat and high carbohydrate diet on molecular profile of inflammation in animal model of obesity in asthma

2019/35/B/NZ5/02906

Keywords:

asthma obesity diet inflammation

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ3_1: Cell biology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Aleksandra Maria Szczepankiewicz 

Number of co-investigators in the project: 7

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 712 600 PLN

Project start date (Y-m-d): 2020-07-22

Project end date (Y-m-d): 2025-07-21

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (15)
  1. Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study
    Authors:
    Nowakowska J, Olechnowicz A, Langwiński W, Koteluk O, Lemańska Ż, Jóźwiak K, Kamiński K, Łosiewski W, Stegmayr J, Wagner D, Alsafadi HN, Lindstedt S, Dziuba M, Bielicka A, Graczyk Z, Szczepankiewicz A.
    Academic press:
    J Asthma (rok: 2022, tom: -, strony: 45667), Wydawca: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/02770903.2022.2056896 - link to the publication
  2. Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study
    Authors:
    Nowakowska J, Olechnowicz A, Langwiński W, Koteluk O, Lemańska Ż, Jóźwiak K, Kamiński K, Łosiewski W, Stegmayr J, Wagner D, Alsafadi HN, Lindstedt S, Dziuba M, Bielicka A, Graczyk Z, Szczepankiewicz A.
    Academic press:
    J Asthma (rok: 2022, tom: -, strony: 45667), Wydawca: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/02770903.2022.2056896 - link to the publication
  3. Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression.
    Authors:
    Langwiński W, Szczepankiewicz D, Narożna B, Stegmayr J, Wagner D, Alsafadi H, Lindstedt S, Stachowiak Z, Nowakowska J, Skrzypski M, Szczepankiewicz A.
    Academic press:
    Mol Immunol (rok: 2022, tom: 147, strony: 115-125), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molimm.2022.04.017 - link to the publication
  4. Allergic Inflammation Alters microRNA Expression Profile in Adipose Tissue in the Rat.
    Authors:
    Szczepankiewicz D, Langwiński W, Kołodziejski P, Pruszyńska-Oszmałek E, Sassek M, Nowakowska J, Chmurzyńska A, Nowak KW, Szczepankiewicz A.
    Academic press:
    Genes (rok: 2020, tom: 11(9), strony: 1034), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11091034 - link to the publication
  5. Effect of miR-223-3p and miR-328a-3p Knockdown on Allergic Airway Inflammation in Rat Precision-Cut Lung Slices
    Authors:
    Joanna Nowakowska, Maria Kachel, Wojciech Langwiński, Kamil Ziarniak, Aleksandra Szczepankiewicz
    Academic press:
    Cells (rok: 2025, tom: 14(2), strony: 104), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells14020104 - link to the publication
  6. Allergic Inflammation Alters microRNA Expression Profile in Adipose Tissue in the Rat.
    Authors:
    Szczepankiewicz D, Langwiński W, Kołodziejski P, Pruszyńska-Oszmałek E, Sassek M, Nowakowska J, Chmurzyńska A, Nowak KW, Szczepankiewicz A.
    Academic press:
    Genes (rok: 2020, tom: 11(9), strony: 1034), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11091034 - link to the publication
  7. Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children
    Authors:
    Joanna Nowakowska, Paulina Sobkowiak, Anna Breborowicz, Magdalena Mrówczynska, Irena Wojsyk-Banaszak, Aleksandra Szczepankiewicz
    Academic press:
    Medicina (rok: 2021, tom: 57, strony: 1341), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  8. Allergic Inflammation Alters microRNA Expression Profile in Adipose Tissue in the Rat.
    Authors:
    Szczepankiewicz D, Langwiński W, Kołodziejski P, Pruszyńska-Oszmałek E, Sassek M, Nowakowska J, Chmurzyńska A, Nowak KW, Szczepankiewicz A.
    Academic press:
    Genes (rok: 2020, tom: 11(9), strony: 1034), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11091034 - link to the publication
  9. Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children
    Authors:
    Joanna Nowakowska, Paulina Sobkowiak, Anna Breborowicz, Magdalena Mrówczynska, Irena Wojsyk-Banaszak, Aleksandra Szczepankiewicz
    Academic press:
    Medicina (rok: 2021, tom: 57, strony: 1341), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  10. Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children
    Authors:
    Joanna Nowakowska, Paulina Sobkowiak, Anna Breborowicz, Magdalena Mrówczynska, Irena Wojsyk-Banaszak, Aleksandra Szczepankiewicz
    Academic press:
    Medicina (rok: 2021, tom: 57, strony: 1341), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  11. Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study
    Authors:
    Nowakowska J, Olechnowicz A, Langwiński W, Koteluk O, Lemańska Ż, Jóźwiak K, Kamiński K, Łosiewski W, Stegmayr J, Wagner D, Alsafadi HN, Lindstedt S, Dziuba M, Bielicka A, Graczyk Z, Szczepankiewicz A.
    Academic press:
    J Asthma (rok: 2022, tom: -, strony: 45667), Wydawca: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/02770903.2022.2056896 - link to the publication
  12. Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression.
    Authors:
    Langwiński W, Szczepankiewicz D, Narożna B, Stegmayr J, Wagner D, Alsafadi H, Lindstedt S, Stachowiak Z, Nowakowska J, Skrzypski M, Szczepankiewicz A.
    Academic press:
    Mol Immunol (rok: 2022, tom: 147, strony: 115-125), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molimm.2022.04.017 - link to the publication
  13. Nitric Oxide Synthase 2 Promoter Polymorphism Is a Risk Factor for Allergic Asthma in Children
    Authors:
    Joanna Nowakowska, Paulina Sobkowiak, Anna Breborowicz, Magdalena Mrówczynska, Irena Wojsyk-Banaszak, Aleksandra Szczepankiewicz
    Academic press:
    Medicina (rok: 2021, tom: 57, strony: 1341), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  14. Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression.
    Authors:
    Langwiński W, Szczepankiewicz D, Narożna B, Stegmayr J, Wagner D, Alsafadi H, Lindstedt S, Stachowiak Z, Nowakowska J, Skrzypski M, Szczepankiewicz A.
    Academic press:
    Mol Immunol (rok: 2022, tom: 147, strony: 115-125), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molimm.2022.04.017 - link to the publication
  15. Allergic Inflammation Alters microRNA Expression Profile in Adipose Tissue in the Rat.
    Authors:
    Szczepankiewicz D, Langwiński W, Kołodziejski P, Pruszyńska-Oszmałek E, Sassek M, Nowakowska J, Chmurzyńska A, Nowak KW, Szczepankiewicz A.
    Academic press:
    Genes (rok: 2020, tom: 11(9), strony: 1034), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11091034 - link to the publication

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