Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Determination of mechanisms and critical molecular partners controlling the multidrug resistance proteins (P-gp and BCRP) expression and functionality in the thyroid carcinoma model.

2018/29/B/NZ3/02642

Keywords:

multidrug-resistance cancers drug pumps signaling pathways thyroid cancers

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Centrum Medyczne Kształcenia Podyplomowego, Studium Kliniczno-Dydaktyczne

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marlena Godlewska 

Number of co-investigators in the project: 5

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 892 290 PLN

Project start date (Y-m-d): 2019-02-04

Project end date (Y-m-d): 2024-02-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Analysis of the Role of FRMD5 in the Biology of Papillary Thyroid Carcinoma
    Authors:
    Gaweł AM, Ratajczak M, Gajda E, Grzanka M, Paziewska A, Cieślicka M, Kulecka M, Oczko-Wojciechowska M, Godlewska M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(13), strony: 6726), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22136726 - link to the publication
  2. Combinatory Treatment with miR-7-5p and Drug-Loaded Cubosomes Effectively Impairs Cancer Cells
    Authors:
    Gajda E, Godlewska M, Mariak Z, Nazaruk E, Gawel D.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(14), strony: 5039), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21145039 - link to the publication
  3. The role of miRNA-7 in the biology of cancer and modulation of drug resistance
    Authors:
    Gajda E, Grzanka M, Godlewska M, Gawel D.
    Academic press:
    Pharmaceuticals (rok: 2021, tom: 14, strony: 149), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ph14020149 - link to the publication
  4. Novel Inhibitor-Based Therapies for Thyroid Cancer-An Update
    Authors:
    Ratajczak M, Gaweł D, Godlewska M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(21), strony: 11829), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111829 - link to the publication

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