Projects funded by the NCN

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246 projects found matching your search criteria :

  1. Application of voltammetry and gravimetry for simultaneous detection of matrix metalloproteinases -1, -2 and -9 in human...

    Call: OPUS 18 , Panel: ST4

    Principal investigator: prof. Anna Maria Nowicka

    Uniwersytet Warszawski, Wydział Chemii

  2. The KLIKK proteases of human pathogen Tannerella forsythia: putative virulence factors with unique biochemical and struc...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  3. The effects of carbamylation on the activity and biological function of Angiotensin I Converting Enzyme (ACE1)

    Call: PRELUDIUM 18 , Panel: NZ1

    Principal investigator: Marta Kamińska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  4. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta - Jankowska

    Uniwersytet Gdański, Wydział Chemii

  5. Biodegradation of estrogens using advanced immobilized oxidoreductases-based biocatalytic systems

    Call: SONATA 15 , Panel: ST8

    Principal investigator: dr Jakub Łukasz Zdarta

    Politechnika Poznańska, Wydział Technologii Chemicznej

  6. Binding isotope effects as new, unique tool for studies of receptor - ligand interactions

    Call: MAESTRO 1 , Panel: ST4

    Principal investigator: prof. Piotr Paneth

    Politechnika Łódzka

  7. Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

    Call: SONATA 15 , Panel: NZ3

    Principal investigator: dr Barbara Anna Kutryb-Zając

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  8. Crystallography of DNA repair enzymes as a tool to study substrate specifity and a mechanism of inhibition

    Call: HARMONIA 1 , Panel: NZ1

    Principal investigator: prof. Barbara Alicja Tudek

    Instytut Biochemii i Biofizyki PAN

  9. Changes of the profile of fruits polyphenolic compounds under the influence of high pressure considering the activity of...

    Call: PRELUDIUM 17 , Panel: NZ9

    Principal investigator: Justyna Szczepańska

    Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

  10. Novel families of ADP-ribosyltransferases and proteins involved in ADP-ribosylation.

    Call: OPUS 17 , Panel: NZ2

    Principal investigator: dr hab. Krzysztof Piotr Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  11. Dietary polyphenols as thyroid peroxidase (TPO) modulators with multidirectional biological activity - a combined in vit...

    Call: OPUS 17 , Panel: NZ9

    Principal investigator: prof. Urszula Katarzyna Gawlik

    Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

  12. The application of the theoretical methods in studies on enzyme CAL-B -aided hydrolysis of phosphine oxides and P-borane...

    Call: PRELUDIUM 1 , Panel: ST4

    Principal investigator: Grzegorz Krasiński

    Centrum Badań Molekularnych i Makromolekularnych PAN

  13. How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

    Call: SONATINA 3 , Panel: NZ2

    Principal investigator: dr Tomasz M. Kuliński

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  14. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Maciej Filip Dawidowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  15. Structure and function of fumarate-adding gltcyl radical enzymes: biochemistry, modeling and application

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: prof. Maciej Szaleniec

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  16. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise...

    Call: PRELUDIUM 16 , Panel: NZ9

    Principal investigator: dr Monika Anna Pliszka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  17. Search for structure-antimicrobial activity correlation for selected boraheterocycles

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Sergiusz Mariusz Luliński

    Politechnika Warszawska, Wydział Chemiczny

  18. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Maria Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  19. Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  20. Structural and functional characterization of loci determining the content of cell wall-bound phenolics under the condit...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Tomasz Hura

    Instytut Fizjologii Roślin im. Franciszka Górskiego PAN

  21. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  22. Inhibition of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa by targeting the enzyme dynamics

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr hab. Krzysztof Brzeziński

    Instytut Chemii Bioorganicznej PAN

  23. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska, Wydział Chemiczny

  24. Stomach microbiome in Helicobacter pyliri-infected patients

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Krystyna Dąbrowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  25. Iron enzymes involved in biosynthesis of antibiotics - molecular activity mechanisms

    Call: OPUS 1 , Panel: ST4

    Principal investigator: prof. Ewa Brocławik

    POLSKA AKADEMIA UMIEJĘTNOŚCI

  26. The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil...

    Call: OPUS 1 , Panel: NZ9

    Principal investigator: dr Anna Ewa Dąbrowska

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

  27. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  28. The role of ectomycorrhizas in carbon and nitrogen cycling in a forest ecosystem

    Call: SONATA 1 , Panel: NZ8

    Principal investigator: dr Lidia Katarzyna Trocha

    Instytut Dendrologii PAN

  29. Dissecting the mechanisms of proteolytic cross-talk underlying pyroptosis, a programmed inflammatory cell death.

    Call: OPUS 15 , Panel: NZ1

    Principal investigator: dr Marcin Łukasz Poręba

    Politechnika Wrocławska

  30. Factors determining changes in enzymatic activity as well as the functional and genetic diveristy of microorganisms acro...

    Call: OPUS 15 , Panel: NZ9

    Principal investigator: prof. Anna Halina Piotrowska-Długosz

    Uniwersytet Technologiczno-Przyrodniczy im. Jana i Jędrzeja Śniadeckich w Bydgoszczy, Wydział Rolnictwa i Biotechnologii

  31. Amphiphilic copolymers containing polystyrene and polyglycidol blocks with varied architecture and their functionalized ...

    Call: OPUS 15 , Panel: ST4

    Principal investigator: dr hab. Stanisław Kazimierz Słomkowski

    Centrum Badań Molekularnych i Makromolekularnych PAN

  32. Novel biocatalytic systems obtained after enzymes immobilization onto multifunctional materials synthesized via electros...

    Call: PRELUDIUM 15 , Panel: ST8

    Principal investigator: Katarzyna Anna Jankowska

    Politechnika Poznańska, Wydział Technologii Chemicznej

  33. The role of diacylglycerol kinase epsilon, an enzyme of the phosphatidylinositol cycle, in the regulation of LPS-induced...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: prof. Katarzyna Kwiatkowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  34. Enantiomerically pure porphyrins via efficient synthesis of trans-A2B2-porphyrins and biocatalytic resolution of primary...

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: dr Agnieszka Nowak-Król

    Instytut Chemii Organicznej Polska Akademia Nauk

  35. Method of obtaining and biochemical characteristics of the nucleases from a psychrophilic microorganism Desulfotalea psy...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Natalia Maciejewska

    Uniwersytet Gdański, Wydział Chemii

  36. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Edward Sikora

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

  37. Adaptation of electrophoretic methods for the determination of the impact of food components on global DNA methylation.

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Monika Baranowska

    Politechnika Gdańska, Wydział Chemiczny

  38. The study of chitinolytic enzymes, aiming at constructing an artificial chitinosome.

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Wojciech Robert Rypniewski

    Instytut Chemii Bioorganicznej PAN

  39. Tungstene-containing aldehyde oxidoreductase from Aromatoleum aromaticum - study of catalytic reaction mechanism

    Call: PRELUDIUM 14 , Panel: ST4

    Principal investigator: Agnieszka Winiarska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  40. The study of the physiology of yeast Yarrowia lipolytica for decomposing of plastic.

    Call: OPUS 14 , Panel: NZ9

    Principal investigator: dr hab. Aleksandra Maria Mirończuk

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  41. Advanced MxOy/biopolymer hybrid platforms for enzymatic biosensors: Design, characteristic and application

    Call: OPUS 14 , Panel: ST8

    Principal investigator: prof. Teofil Jesionowski

    Politechnika Poznańska, Wydział Technologii Chemicznej

  42. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  43. New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer...

    Call: PRELUDIUM 14 , Panel: ST5

    Principal investigator: Paulina Erwardt

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  44. Effects of pesticides on the red mason bee Osmia bicornis in agricultural landscapes: mixture toxicity and the evolution...

    Call: SONATA 13 , Panel: NZ8

    Principal investigator: dr Agnieszka Bednarska

    Instytut Ochrony Przyrody PAN

  45. Molecular origins of mechanisms governing biological functions of enzymes with buried actives sites: substrate inhibitio...

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr Jan Brezovsky

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  46. Aminophosphonates bearing fluorine atoms as inhibitors odf aminopeptideses and their potential application for determina...

    Call: HARMONIA 9 , Panel: ST5

    Principal investigator: prof. Paweł Kazimierz Kafarski

    Politechnika Wrocławska

  47. Dual-function tail phage proteins- determination of the function and the mechanism of action towards (poly)saccharides

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr Ewa Brzozowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  48. Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

    Call: HARMONIA 9 , Panel: NZ1

    Principal investigator: prof. Zuzanna Drulis-Kawa

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  49. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  50. Biomedical materials modification by proteolytic enzymes inhibitors

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Anna Beata Jarosz-Wilkołazka

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

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