Projects funded by the NCN


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234 projects found matching your search criteria :

  1. How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

    Call: SONATINA 3 , Panel: NZ2

    Principal investigator: dr Tomasz Kuliński

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  2. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Maciej Dawidowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  3. Structure and function of fumarate-adding gltcyl radical enzymes: biochemistry, modeling and application

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: prof. Maciej Szaleniec

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

  4. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise...

    Call: PRELUDIUM 16 , Panel: NZ9

    Principal investigator: dr Monika Pliszka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  5. Search for structure-antimicrobial activity correlation for selected boraheterocycles

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Sergiusz Luliński

    Politechnika Warszawska, Wydział Chemiczny

  6. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  7. Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: prof. Paweł Bednarek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  8. Structural and functional characterization of loci determining the content of cell wall-bound phenolics under the condit...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Tomasz Hura

    Instytut Fizjologii Roślin im. Franciszka Górskiego Polskiej Akademii Nauk

  9. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  10. Inhibition of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa by targeting the enzyme dynamics

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr hab. Krzysztof Brzeziński

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  11. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska

  12. Stomach microbiome in Helicobacter pyliri-infected patients

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Krystyna Dąbrowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  13. Iron enzymes involved in biosynthesis of antibiotics - molecular activity mechanisms

    Call: OPUS 1 , Panel: ST4

    Principal investigator: prof. Ewa Brocławik

    POLSKA AKADEMIA UMIEJĘTNOŚCI

  14. The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil...

    Call: OPUS 1 , Panel: NZ9

    Principal investigator: dr Anna Dąbrowska

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

  15. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  16. The role of ectomycorrhizas in carbon and nitrogen cycling in a forest ecosystem

    Call: SONATA 1 , Panel: NZ8

    Principal investigator: dr Lidia Trocha

    Instytut Dendrologii PAN

  17. Dissecting the mechanisms of proteolytic cross-talk underlying pyroptosis, a programmed inflammatory cell death.

    Call: OPUS 15 , Panel: NZ1

    Principal investigator: dr Marcin Poręba

    Politechnika Wrocławska, Wydział Chemiczny

  18. Factors determining changes in enzymatic activity as well as the functional and genetic diveristy of microorganisms acro...

    Call: OPUS 15 , Panel: NZ9

    Principal investigator: prof. Anna Piotrowska-Długosz

    Politechnika Bydgoska im. Jana i Jędrzeja Śniadeckich, Wydział Rolnictwa i Biotechnologii

  19. Amphiphilic copolymers containing polystyrene and polyglycidol blocks with varied architecture and their functionalized ...

    Call: OPUS 15 , Panel: ST4

    Principal investigator: dr hab. Stanisław Słomkowski

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  20. Novel biocatalytic systems obtained after enzymes immobilization onto multifunctional materials synthesized via electros...

    Call: PRELUDIUM 15 , Panel: ST8

    Principal investigator: Katarzyna Jankowska

    Politechnika Poznańska, Wydział Technologii Chemicznej

  21. The role of diacylglycerol kinase epsilon, an enzyme of the phosphatidylinositol cycle, in the regulation of LPS-induced...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: prof. Katarzyna Kwiatkowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

  22. Enantiomerically pure porphyrins via efficient synthesis of trans-A2B2-porphyrins and biocatalytic resolution of primary...

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: dr Agnieszka Nowak-Król

    Instytut Chemii Organicznej Polska Akademia Nauk

  23. Method of obtaining and biochemical characteristics of the nucleases from a psychrophilic microorganism Desulfotalea psy...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Natalia Maciejewska

    Uniwersytet Gdański, Wydział Chemii

  24. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Sikora

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  25. Adaptation of electrophoretic methods for the determination of the impact of food components on global DNA methylation.

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Monika Baranowska

    Politechnika Gdańska, Wydział Chemiczny

  26. The study of chitinolytic enzymes, aiming at constructing an artificial chitinosome.

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Wojciech Rypniewski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  27. Tungstene-containing aldehyde oxidoreductase from Aromatoleum aromaticum - study of catalytic reaction mechanism

    Call: PRELUDIUM 14 , Panel: ST4

    Principal investigator: Agnieszka Winiarska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

  28. The study of the physiology of yeast Yarrowia lipolytica for decomposing of plastic.

    Call: OPUS 14 , Panel: NZ9

    Principal investigator: dr hab. Aleksandra Mirończuk

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  29. Advanced MxOy/biopolymer hybrid platforms for enzymatic biosensors: Design, characteristic and application

    Call: OPUS 14 , Panel: ST8

    Principal investigator: prof. Teofil Jesionowski

    Politechnika Poznańska, Wydział Technologii Chemicznej

  30. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  31. New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer...

    Call: PRELUDIUM 14 , Panel: ST5

    Principal investigator: Paulina Erwardt

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  32. Effects of pesticides on the red mason bee Osmia bicornis in agricultural landscapes: mixture toxicity and the evolution...

    Call: SONATA 13 , Panel: NZ8

    Principal investigator: dr Agnieszka Bednarska

    Instytut Ochrony Przyrody Polskiej Akademii Nauk

  33. Molecular origins of mechanisms governing biological functions of enzymes with buried actives sites: substrate inhibitio...

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr hab. Jan Brezovsky

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  34. Aminophosphonates bearing fluorine atoms as inhibitors odf aminopeptideses and their potential application for determina...

    Call: HARMONIA 9 , Panel: ST5

    Principal investigator: prof. Paweł Kafarski

    Politechnika Wrocławska

  35. Dual-function tail phage proteins- determination of the function and the mechanism of action towards (poly)saccharides

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr Ewa Brzozowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  36. Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

    Call: HARMONIA 9 , Panel: NZ1

    Principal investigator: prof. Zuzanna Drulis-Kawa

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  37. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  38. Biomedical materials modification by proteolytic enzymes inhibitors

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Anna Jarosz-Wilkołazka

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  39. Functions of Fusarium-produced lytic enzymes and mycotoxins in pathogenesis and of metabolites responsible for plant def...

    Call: OPUS 13 , Panel: NZ9

    Principal investigator: prof. Łukasz Stępień

    Instytut Genetyki Roślin Polskiej Akademii Nauk

  40. The role of reactive oxygen species (ROS) generated during a maximal exercise by endothelial NOX2 i NOX4 in the regulati...

    Call: PRELUDIUM 13 , Panel: NZ4

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  41. Changes at different levels of body organization in adult specimens of Lithobius forficatus exposed to continuous cadmiu...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Magdalena Rost-Roszkowska

    Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych

  42. Analysis of molecular mechanisms of frost tolerance in Lolium multiflorum/Festuca arundinacea introgression forms

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: Adam Augustyniak

    Instytut Genetyki Roślin Polskiej Akademii Nauk

  43. The effect of lead on the generation of signal molecules and their impact on the regulation of flavonoid biosynthesis in...

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: dr Agnieszka Woźniak

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Bioinżynierii

  44. The effect of molecular structure of starch depolymerisation products, obtained by controlled microwave heating, on thei...

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: dr Kamila Kapuśniak

    Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie, Wydział Matematyczno-Przyrodniczy

  45. Structural studies on inhibition mechanisms of enzymes belonging to USP family, which remove ubiquitin from eukaryotic p...

    Call: SONATINA 1 , Panel: NZ1

    Principal investigator: dr Marcin Ziemniak

    Uniwersytet Warszawski, Wydział Chemii

  46. Promutagenic function of ubiquitin enzyme variant Mms2 in S. cerevisiae cells.

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Michał Krawczyk

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  47. Synthesis of 2-phosphonocarboxylates as potential covalent inhibitors of Rab geranylgeranyl transferase

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Joanna Małolepsza

    Politechnika Łódzka, Wydział Chemiczny

  48. New examples of enzyme catalytic promiscuity. Enzyme-catalyzed transformations of imines: stereoselective nitroalkane ad...

    Call: OPUS 12 , Panel: ST5

    Principal investigator: prof. Piotr Kiełbasiński

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  49. Solid phase microextraction-based universal analytical platform for assessment of in vitro generated metabolism

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Karol Jaroch

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  50. Cytoplasmic enzymes of pathogenic fungi Candida spp. that moonlight as adhesins on the cell wall - structural determinan...

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: prof. Andrzej Kozik

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii