Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Foldameric miniproteins - structure and catalytic function

2016/21/B/ST5/00269

Keywords:

foldamers peptides artificial enzymes

Descriptors:

  • ST5_22:
  • ST5_18:
  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Łukasz Berlicki 

Number of co-investigators in the project: 9

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 623 100 PLN

Project start date (Y-m-d): 2017-02-09

Project end date (Y-m-d): 2020-12-08

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spektrometr dichroizmu kołowego (300 000 PLN)
  2. komputer z monitorem.
  3. laboratoryjny system do oczyszczania wody.
  4. Automatyczny syntezator peptydów z mikrofalami (300 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Constrained beta-amino acid-containing miniproteins
    Authors:
    Magda Drewniak-Świtalska, Barbara Barycza, Ewa Rudzińska-Szostak, Paweł Morawiak, Łukasz Berlicki
    Academic press:
    Organic and Biomolecular Chemistry (rok: 2021, tom: 19, strony: 4272-4278), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D1OB00309G - link to the publication
  2. Towards foldameric miniproteins – a helix turn helix motif
    Authors:
    Katarzyna Ożga, Magda Drewniak-Świtalska, Ewa Rudzińska-Szostak, Łukasz Berlicki
    Academic press:
    ChemPlusChem (rok: 2021, tom: 86, strony: 646-649), Wydawca: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/cplu.202100090 - link to the publication
  3. Design and Engineering of Miniproteins
    Authors:
    K. Ożga, Ł. Berlicki
    Academic press:
    ACS Bio & Med Chem Au , Wydawca: American Chemical Society
    Status:
    Accepted for publication
    DOI:
    10.1021/acsbiomedchemau.2c00008 - link to the publication
  4. Miniprotein-based artificial retroaldolase
    Authors:
    K. Ożga, Ł. Berlicki
    Academic press:
    Angewandte Chemie Int. Ed. , Wydawca: Wiley
    Status:
    Submitted
    DOI:
    brak - link to the publication
  5. A computationally designed β-amino acid-containing miniprotein
    Authors:
    Magdalena Bejger, Paulina Fortuna, Magda Drewniak-Świtalska, Jacek Plewka, Wojciech Rypniewski, Łukasz Berlicki
    Academic press:
    Chemical Communications (rok: 2021, tom: 57, strony: 6015-6018), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D1CC02192C - link to the publication

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