Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Intensification of multicomponent and cascade reactions by liposome and biocatalytic methodologies

2014/14/M/ST5/00030

Keywords:

liposomes enzymes oxidation transaminases lipophilic oxidase reductase cascades

Descriptors:

  • ST5_16:
  • ST8_8: Mechanics of solids
  • ST5_18:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Chemii Organicznej PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ryszard Ostaszewski 

Number of co-investigators in the project: 7

Call: HARMONIA 6 - announced on 2014-06-16

Amount awarded: 972 920 PLN

Project start date (Y-m-d): 2015-06-08

Project end date (Y-m-d): 2019-03-07

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (12)
  1. Bioreactor for the Continuous Purification of Simvastatin by Lovastatin Esterase
    Authors:
    W. Kurek, D. Koszelewski, , R. Ostaszewski, A. Żadło
    Academic press:
    Process Biochemistry (rok: 2017, tom: 60, strony: 92-97), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.procbio.2017.05.026 - link to the publication
  2. Efficient Passerini reactions in an aqueous vesicle system
    Authors:
    D. Paprocki, D. Koszlewski, P. Walde , R. Ostaszewski
    Academic press:
    RSC Advances (rok: 2015, tom: 5, strony: 102828-102835), Wydawca: ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
    Status:
    Published
    DOI:
    10.1039/C5RA22258C - link to the publication
  3. Enantioselective Reduction of Ethyl 3-oxo-5-phenylpentanoate with Whole-Cell Biocatalysts
    Authors:
    A. Żadło, J. H. Schrittwieser, D. Koszelewski, W. Kroutil, R. Ostaszewski
    Academic press:
    European Journal of Organic Chemistry (rok: 2016, tom: 5, strony: 1007-1011), Wydawca: WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
    Status:
    Published
    DOI:
    10.1002/ejoc.201501460 - link to the publication
  4. Enzymatic Ugi Reaction with Amines and Cyclic Imines
    Authors:
    A. Żądło-Dobrowolska, S. Kłossowski, D. Koszelewski, D. Paprocki, R. Ostaszewski
    Academic press:
    Chemistry - A European Journal (rok: 2016, tom: 22, strony: 16684-16689), Wydawca: WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
    Status:
    Published
    DOI:
    10.1002/chem.201603412 - link to the publication
  5. Facile Conversion of α-Acyloxy Amides into 3-Hydroxy-lactams
    Authors:
    Dominik Koszelewski, Damian Trzepizur, Ewelina Zaorska, Arleta Madej, Anna Brodzka, Daniel Paprocki, Filip Borys, Monika Wilk, Ryszard Ostaszewski
    Academic press:
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (rok: 2018, tom: 25, strony: 3280-3290), Wydawca: WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY
    Status:
    Published
    DOI:
    10.1002/ejoc.201800605 - link to the publication
  6. Efficient Ugi reactions in an aqueous vesicle system
    Authors:
    A. Madej, D. Paprocki, D. Koszelewski, A. Żądło-Dobrowolska, A. Brzozowska, P. Walde, R. Ostaszewski,
    Academic press:
    RSC Advances (rok: 2017, tom: 7, strony: 33344-33354), Wydawca: Royal Soceity of Chemistry
    Status:
    Published
    DOI:
    10.1039/c7ra03376a - link to the publication
  7. Environmentally friendly approach to α-acyloxy carboxamides via a chemoenzymatic cascade
    Authors:
    D. Paprocki, D. Koszelewski, A. Żądło, P. Walde, R. Ostaszewski
    Academic press:
    RSC Advances (rok: 2016, tom: 6, strony: 68231-68237), Wydawca: ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
    Status:
    Published
    DOI:
    10.1039/C6RA13078J - link to the publication
  8. Enzymatic tandem approach to Knoevenagel condensation of acetaldehyde with acidic methylene compounds in organic media
    Authors:
    D. Koszelewski, D. Paprocki, A. Madej, Filip Borys, A. Brodzka, R. Ostaszewski
    Academic press:
    European Journal of Organic Chemistry (rok: 2017, tom: 31, strony: 4572–4579), Wydawca: ChemPubSoc Europe
    Status:
    Published
    DOI:
    10.1002/ejoc.201700936 - link to the publication
  9. Enzyme-promoted Asymmetric Tandem Passerni Reaction
    Authors:
    A. Żądło-Dobrowolska, D. Koszelewski, D. Paprocki, A. Madej, M. Wilk, R. Ostaszewski
    Academic press:
    ChemCatChem (rok: 2017, tom: 9, strony: 3047-3053), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/cctc.201700427 - link to the publication
  10. Soft and dispersed interface- rich aqueous systems that promote and guide chemical reactions
    Authors:
    Sandra Serrano- Luginbühl, Kepa Ruiz- Mirazo, Ryszard Ostaszewski, Fabrice Gallou, Peter Walde
    Academic press:
    NATURE REVIEWS CHEMISTRY (rok: 2018, tom: 2, strony: 306-327), Wydawca: NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
    Status:
    Published
    DOI:
    10.1038/ - link to the publication
  11. The studies on the chemoenzymatic synthesis of 2-benzyl-3-butenoic acid
    Authors:
    Filip Borys, Daniel Paprocki, Dominik Koszelewski, Ryszard Ostaszewski
    Academic press:
    Catalysis Communications (rok: 2018, tom: 23, strony: 45452), Wydawca: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.catcom.2018.05.020 - link to the publication
  12. Catalyst‑free synthesis of α‑acyloxycarboxamides in aqueous media
    Authors:
    Daniel Paprock, Monika Wilk, Arleta Madej, Peter Walde, Ryszard Ostaszewski
    Academic press:
    Environmental Chemistry Letters (rok: 2019, tom: 17, strony: 1011 - 1016), Wydawca: SPRINGER HEIDELBERG TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
    Status:
    Published
    DOI:
    10.1007/s10311-018-0797-5 - link to the publication

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