Projects funded by the NCN


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47 projects found matching your search criteria :

  1. Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases

    Call: SONATA 9 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej PAN

  2. Fluorescent oligonucleotide probes based on i-motif structures with use cytosine analogue tC

    Call: PRELUDIUM 8 , Panel: ST4

    Principal investigator: Patrycja Bielecka

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  3. Oligonucleotide-based fluorescent probes at the lipid monolayer / aqueous solution interface. Monitoring of the concentr...

    Call: OPUS 1 , Panel: ST4

    Principal investigator: prof. Bernard Juskowiak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  4. The use of chemically modified antisense oligonucleotides in the experimental therapy against Myotonic Dystrophy (DM).

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr Ewa Stepniak-Konieczna

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  5. Reconstitution and modification of cofactors of antenna complex LHCII

    Call: PRELUDIUM 7 , Panel: NZ1

    Principal investigator: Maciej Michalik

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  6. RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Zofia Gdaniec

    Instytut Chemii Bioorganicznej PAN

  7. Vitamin B12 as a delivery vehicle for antibacterial oligonucleotide analogues

    Call: SYMFONIA 2 , Panel: ST5

    Principal investigator: dr hab. Dorota Gryko

    Instytut Chemii Organicznej PAN

  8. Studies on biosensor's receptor layers composed of oligonucleotides

    Call: PRELUDIUM 1 , Panel: ST4

    Principal investigator: Robert Ziółkowski

    Politechnika Warszawska, Wydział Chemiczny

  9. Polymeric stationary phases containing gold and silver nanoparticles in analytics of biologically active compounds

    Call: PRELUDIUM 6 , Panel: ST4

    Principal investigator: Damian Grzywiński

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  10. Exploring the Mutual Interactions between RNA Enantiomers

    Call: PRELUDIUM 6 , Panel: NZ1

    Principal investigator: Marta Dudek

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  11. Modified chlorophyll derivatives and its RNA hybrid conjugates for modern photomedicine

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Michał Kotkowiak

    Politechnika Poznańska, Wydział Fizyki Technicznej

  12. Structure defined oligonucleotides for revealing fundamental insights into structure and function of RNAs

    Call: MAESTRO 4 , Panel: ST5

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  13. Conserved RNA structural motifs in influenza virus: toward revealing viral RNA functions

    Call: HARMONIA 4 , Panel: NZ1

    Principal investigator: dr hab. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej PAN

  14. Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche...

    Call: MAESTRO 4 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii

  15. Study of the mechanism of ultrasound and water steam blanching as pretreatments before microwave-convective drying of se...

    Call: PRELUDIUM 4 , Panel: NZ9

    Principal investigator: dr Magdalena Dadan

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Nauk o Żywności

  16. Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

    Call: OPUS 4 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  17. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr Ewelina Zabost

    Uniwersytet Warszawski, Wydział Chemii

  18. New approaches towards modulating selective and functional activities of antisense oligonucleotides

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  19. (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

    Call: JPND Call 2023 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  20. Adsorbent's type vs. adsorption efficiency of undesirable substances from edible niche oils

    Call: PRELUDIUM 22 , Panel: NZ9

    Principal investigator: Kamil Czwartkowski

    Uniwersytet Ekonomiczny we Wrocławiu, Wydział Inżynierii Produkcji

  21. Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr Marta Szabat

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  22. Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  23. Formation of the stability, bioavailability and bioaccessibility of plant pigments by microencapsulation in the context ...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Igor Turkiewicz

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  24. P-stereodefined phosphorothioate analogs of 'morpholino" oligonucleotides (sTMO) as a new model of therapeutic nucleic a...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Katarzyna Jastrzębska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  25. Role of antisense oligonucleotide-induced intronic microRNA on axonal morphogenesis in zebrafish

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Savani Anbalagan

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  26. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  27. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  28. Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Hanna Dams-Kozłowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  29. Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectroscopy of nucleic acids

    Call: OPUS 19 , Panel: ST4

    Principal investigator: dr Witold Andrałojć

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  30. Making use of siderophore transport systems to deliver peptide nucleic acids to bacterial cells

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Joanna Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  31. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  32. Antisense oligonucleotides and their nanostructures conjugated with boron clusters; physico-chemical and biological char...

    Call: ETIUDA 8 , Panel: ST4

    Principal investigator: Damian Kaniowski

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  33. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  34. Chlorophylls and carotenoids under high pressure - optical spectroscopy and high pressure in investigations of primary p...

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: prof. Leszek Fiedor

    Uniwersytet Jagielloński

  35. Bacterial toxin-antitoxin systems as novel target for the development of potential antibiotics

    Call: PRELUDIUM 13 , Panel: NZ1

    Principal investigator: dr Marcin Równicki

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  36. Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Elżbieta Sochacka

    Politechnika Łódzka, Wydział Chemiczny

  37. Structural determinants of anticancer properties of G-rich oligonucleotides

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  38. Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  39. The puzzling fate of lupin chromosomes

    Call: PRELUDIUM 12 , Panel: NZ2

    Principal investigator: Wojciech Bielski

    Instytut Genetyki Roślin Polskiej Akademii Nauk

  40. Identification of novel structural variants in patients presenting with congenital limb malformations by means of the ge...

    Call: PRELUDIUM 12 , Panel: NZ2

    Principal investigator: dr Magdalena Socha

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  41. Application of new type of adsorbents and liquid chromatography hyphenated with mass spectrometry for the in vitro metab...

    Call: SONATA BIS 6 , Panel: ST4

    Principal investigator: dr hab. Sylwia Studzińska

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  42. Bifunctional antisense oligonucleotides - optimization of alternative splicing regulation in cancer cell lines

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Jolanta Lisowiec-Wąchnicka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. Double stranded probes, in which both oligonucleotide components hybridize according to the Hoogsteen's interactions, an...

    Call: OPUS 10 , Panel: ST5

    Principal investigator: dr hab. Piotr Guga

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  44. Chromatographic determination of nucleic acids (DNA, RNA) and their constituents (nucleosides, nucleotides, oligonuceoti...

    Call: SONATA 1 , Panel: ST4

    Principal investigator: dr Sylwia Studzińska

    UNIWERSYTET MIKOŁAJA KOPERNIKA, Wydział Chemii, Katedra Chemii Środowiska i Bioanalityki

  45. Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Weronika Kotkowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  46. Interaction of oligonucleotide-based fluorescent probes and Langmuir monolayer, contaning silver nanoclusters (Ag NCs), ...

    Call: PRELUDIUM 10 , Panel: ST4

    Principal investigator: Angelika Świtalska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  47. In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

    Call: OPUS 10 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk